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    Production of taxol from Lasiodiplodia theobromae and biochemical characterization of its 10-deacetylbaccatin III-10-O-acetyltransferase enzyme and evaluation of anticancer activity of enzymatically synthesized baccatin III 

    Sah, Balendra
    Taxol (paclitaxel) originally identified from the inner bark of Taxus brevifolia, is a clinically approved anticancer drug for the treatment of various kinds of cancer, particularly ovarian cancer, breast cancer and Kaposi's ...

    A role for the cohesin complex in subtelomeric gene silencing in Saccharomyces cerevisiae 

    Kothiwal, Deepash
    Chromatin is a dynamic structure which reorganizes to support numerous chromosomal processes. Various histone and non-histone proteins are involved in chromatin organization. One such group of non-histone proteins, known ...

    Understanding the Mechanism of Noncanonical Functions of RAGs in Lymphoid Cancer and Glioblastoma 

    Paranjape, Amita M
    Recombination activating genes (RAGs) composed of RAG1 and RAG2, are the endonuclease involved in V(D)J recombination, which is critical for adaptive immunity in mammals. Activation-induced cytidine deaminase (AID), expressed ...

    Regulation of Flagellar Motility in Giardia lamblia and Trichomonas vaginalis 

    Sudhakar, Aparna
    Protozoan pathogens are responsible for infections that are highly prevalent, especially in developing and under-developed countries. Flagellar motility is exhibited by a variety of organisms ranging from bacteria to certain ...

    Studies on the roles of rffG and rfbB encoding dTDP-glucose 4,6- dehydratase in Salmonella Typhimurium 

    Chakraborty, Subhashish
    Salmonellosis is a major health concern which causes significant morbidity and mortality worldwide. Infection with Salmonella Typhimurium leads to self-limiting diarrhea in healthy individuals and invasive disease in ...

    Roles of Protein Acetylation in the Human Pathogen Helicobacter pylori 

    Kumar, Amrendra
    Helicobacter pylori is a gram-negative epsilon proteobacterium infecting half of the world population. H. pylori is a naturally competent bacterium with a huge repertoire of Restriction-Modification (RM) systems. The ...

    The dual-targeting of Saccharomyces cerevisiae Pso2 into the nucleus and mitochondria is regulated by post-translational modifications: Implications for organelle-specific DNA repair 

    Somashekara, S C
    The repair of DNA interstrand crosslinks (ICLs) involves the concerted action of multiple DNA repair pathways. In eukaryotes, ICLs are sensed and repaired by replication-coupled or replication-independent mechanisms in ...

    Understanding the Long-term Impact and Mechanism of Action of Endosulfan, an Organochlorine Pesticide on Fertility, Development and Growth of Mice 

    Sharma, Anju
    Endosulfan (ES) is one of the major broad-spectrum organochlorine pesticides categorized as Class II (moderately hazardous) by WHO and Class I (highly acutely toxic) by US Environment Protection Agency. Although the use ...

    Understanding Nonhomologous DNA End Joining: Novel Insights Into Mechanism and Regulation 

    Ghosh, Dipayan
    This study has provided new insights into the mechanistic details of NHEJ and showed that DNA sequence around the break site can be a factor in determining which proteins involved in NHEJ might be recruited with a higher ...
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    Stop codon readthrough of NNAT mRNA and its role in neuronal differentiation 

    Pandit, Madhuparna
    Protein synthesis terminates at the first stop codon encountered by the ribosome. In stop codon readthrough, translation termination is suppressed, enabling the ribosomes to continue translation beyond the canonical stop ...
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    AuthorAmbika, D (1)Bakshi, Arindam (1)Balagopal, Deepa (1)Banerjee, Pip (1)Banerjee, Ushashi (1)Beri, Divya (1)Bhattacharya, Supreet (1)Bhatter, Nupur (1)Chakraborty, Subhashish (1)Dahal, Sumedha (1)... View MoreSubject
    NATURAL SCIENCES (48)
    Mitochondria (4)Cancer (3)Helicobacter pylori (3)arginine methylation (2)DNA (2)DNA double-strand breaks (2)DNA repair (2)Escherichia coli (2)G-quadruplex (2)... View MoreHas File(s)Yes (48)

    etd@IISc is a joint service of SERC & J R D Tata Memorial (JRDTML) Library || Powered by DSpace software || DuraSpace
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