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    Understanding the Regulation of mRNA Translation Repression by RGG-motif Proteins 

    Poornima, G
    Messenger RNA translation is one of the most energy expensive steps in the process of gene expression and therefore translation regulation is critical for maintaining cellular homeostasis. In contrast to transcriptional ...

    Understanding the Mechanism of Double-strand Break Repair and Genome Fragility in Mammalian Mitochondria 

    Dahal, Sumedha
    Mitochondria are semiautonomous organelles in a cell as they have their own genome that replicates independently. It plays a major role in oxidative phosphorylation due to which mitochondrial DNA (mtDNA) is frequently ...

    Role of Mycobacterium tuberculosis DinG and UvrD helicases in unwinding G-quadruplex DNA 

    Ambika, D
    Recent studies have demonstrated the role of E. coli UvrD as a replicative helicase that facilitates replication of rolling circle plasmids. Along with dinG and rep helicase, UvrD a so-called “accessory helicase” removes ...

    Untangling the Helicobacter pylori genome: Deciphering the significance of zinc finger motif(s) in Topoisomerase I catalysis 

    Kondekar, Sumedha
    Helicobacter pylori, a human pathogen dominating gastric microbial population, displays differential gene expression during various stages of stomach colonization. Topoisomerases play a crucial role in maintaining DNA ...

    Establishment of human ectopic liver tissue in immunocompromised mice as a model for Hepatitis C Virus studies 

    Jayal, Priyanka
    Infection with hepatitis C virus (HCV) leads to an inflammatory condition which may progress to liver cirrhosis and in some cases, hepato-cellular carcinoma. Though, new drugs are being added to the list of HCV therapeutics, ...

    Regulation of Flagellar Motility in Giardia lamblia and Trichomonas vaginalis 

    Sudhakar, Aparna
    Protozoan pathogens are responsible for infections that are highly prevalent, especially in developing and under-developed countries. Flagellar motility is exhibited by a variety of organisms ranging from bacteria to certain ...

    Studies on the roles of rffG and rfbB encoding dTDP-glucose 4,6- dehydratase in Salmonella Typhimurium 

    Chakraborty, Subhashish
    Salmonellosis is a major health concern which causes significant morbidity and mortality worldwide. Infection with Salmonella Typhimurium leads to self-limiting diarrhea in healthy individuals and invasive disease in ...

    Roles of Protein Acetylation in the Human Pathogen Helicobacter pylori 

    Kumar, Amrendra
    Helicobacter pylori is a gram-negative epsilon proteobacterium infecting half of the world population. H. pylori is a naturally competent bacterium with a huge repertoire of Restriction-Modification (RM) systems. The ...

    The dual-targeting of Saccharomyces cerevisiae Pso2 into the nucleus and mitochondria is regulated by post-translational modifications: Implications for organelle-specific DNA repair 

    Somashekara, S C
    The repair of DNA interstrand crosslinks (ICLs) involves the concerted action of multiple DNA repair pathways. In eukaryotes, ICLs are sensed and repaired by replication-coupled or replication-independent mechanisms in ...

    Understanding the Long-term Impact and Mechanism of Action of Endosulfan, an Organochlorine Pesticide on Fertility, Development and Growth of Mice 

    Sharma, Anju
    Endosulfan (ES) is one of the major broad-spectrum organochlorine pesticides categorized as Class II (moderately hazardous) by WHO and Class I (highly acutely toxic) by US Environment Protection Agency. Although the use ...
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    AuthorAgarwal, Ankit (1)Akhtar, Md Noor (1)Ambika, D (1)Bakshi, Arindam (1)Balagopal, Deepa (1)Banerjee, Pip (1)Banerjee, Ushashi (1)Beri, Divya (1)Bhattacharya, Supreet (1)Bhatter, Nupur (1)... View MoreSubject
    NATURAL SCIENCES (71)
    Cancer (6)Mitochondria (6)DNA repair (4)Helicobacter pylori (3)Salmonella Typhimurium (3)arginine methylation (2)Chromatin (2)DNA (2)DNA double-strand breaks (2)... View MoreHas File(s)Yes (70)No (1)

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