• PSD95 as a biophysical modulator of synaptic communication 

  Dhingra, Vanika

  PSD95 is a core scaffold protein of the postsynaptic density (PSD) at excitatory synapses and a member of the MAGUK family, where it plays a central role in organizing glutamate receptors, ion channels, and signalling ...

• Fermentative productio of DL-Alanine by an Arthrobacter species C19d 

  Rudra Setty, T M

  No Abstract

• Role of micro-organisms in the formation of elemental sulphur in nature with special reference to the sulphur-bearing coastal area of India 

  Iya, K K

  No Abstract

• Importance of formylation in eubacterial translation initiation 

  Vethantham, Vasupradha

  Initiation of protein synthesis in all organisms occurs with the amino acid methionine. In the case of eubacteria and eukaryotic organelles, methionine is further modified to formylmethionine by the enzyme methionyl?tRNA ...

• Role of Queuosine in Codon-Anticodon Interaction 

  Oruganty, Aparna

  The speed and accuracy of the process of protein synthesis is very high. The major step at which the fidelity of translation is governed is at the step of codon?anticodon pairing. An erroneous codon?anticodon pairing can ...

• Purification and characterization of DNA-dependent RNA polymerase II from candida utilis 

  Patturajan, Meera

  Abstract not available

• Molecular characterisation of Saccharomyces cerevisiae Prp17protein and its interacting partners 

  Mannan, Ashraf-Ul

  In majority of eukaryotic genes, removal of intervening sequences from pre?mRNA is essential for its expression. A ribonucleoprotein complex called the spliceosome catalyses the removal of intron by two sequential ...

• Genome-wide and structural analyses of signalling proteins with special reference to protein kinases 

  Krupa, A

  The work done in the dissertation involves genome?wide sequence analysis on the Plasmodium falciparum proteins with a broad objective of understanding further the functional diversity and evolution. P. falciparum is one ...

• X-ray crystallographic studies of amino acid-carboxylic acid complexes 

  Suresh, A Stephen

  The structure, assembly and action of proteins critically depend upon non?covalent interactions. A programme aimed at elucidating the atomic details of such interactions using an approach involving the preparation and X?ray ...

• Exploration of some components of fatty acid biosynthesis in prokaryotes and eukaryotes : PANK of homo sapiens and fabl of plasmodium falciparum 

  Thyagarajan, Kalyani

  Coenzyme A (CoA) is a central molecule that plays a key role in this process. In the course of this project, we have attempted to address some key questions that deal with an enzyme involved in CoA biosynthesis (Pantothenate ...

• Studies on thermo-resistant bacilli 

  Bilimoria, Minoo H

  A beginning was made in this country in the systematic study of spore‑forming bacteria capable of growing at 55°C. Ninety‑five odd isolates were obtained from sources such as soils, water from hot springs, air, dust, and ...

• Ecologically sound integrated regional energy planning 

  Ramachandra, T V

  The central theme of the integrated energy plan would be to prepare an area-based decentralised energy plan to meet energy needs for subsistence and development of alternate energy sources at least cost to the economy and ...

• Antifungal antibiotics by actinomycetes formation of champamycin - B By Streptomyces Champavatii 

  Uma, B N

  Presently, the chemotherapeutic treatment of the widely prevalent fungal infections in humans, animals and plants is far from satisfactory and is in marked contrast to that of bacterial diseases which are controlled successfully ...

• Design of a thermostable pan-sarbecovirus vaccine 

  Srivastava, Simran

  Coronaviruses (CoVs) are a global health threat due to their potential for widespread transmission including in humans. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent responsible for ...

• Characterizing the role of claudins in C. elegans neurons 

  Ahuja, Aishwarya

  Cell adhesion molecules (CAMs) play important roles in neurons, contributing to nervous system development, synapse formation and plasticity. A subset of CAMs, Claudins, known for their roles at tight junctions, remain ...

• Understanding the physiological role of ITPK1-type inositol phosphate kinase in embryophytes 

  Pullagurla, Naga Jyothi

  Land plants have evolved sophisticated mechanisms to adapt to phosphate (Pi) limitation, yet such regulatory networks in nonvascular bryophytes remain poorly understood. Here, we show that both male and female liverworts ...

• Structure andinteractions of polyamines 

  Ramaswamy, S

  Polyamines are ubiquitous biological cations. Their high concentration in cells, increase in rapidly growing tissues and the regulatory mechanisms that have evolved for controlling them, point to the importance of polyamines ...

• Conformational studies on peptides containing alpha aminoisobutyric acid and polypeptides with alternating LD-Sequences 

  Prasad, B V Venkataram

  The results of semiempirical energy calculations on poly(Aib), varying ACO and ?(NC?C) separately and simultaneously, suggest a novel fourfold helical structure as an energetically favourable model for poly(Aib). This novel ...

• Conformational analysis of cyclic peptides containing Cis peptide units 

  Ramnarayan, K

  The dimensions of the cis peptide unit obtained as an average from the three sets of data viz., cyclic di-, higher, and tripeptides are summarized in Table 2.11. On a close examination of the Table, the following salient ...

• RNA granules and DNA damage: Exploring the role of posttranscriptional gene control upon genotoxic stress 

  Mohanan, Gayatri

  Cells constantly encounter genotoxic stress arising from extrinsic environmental factors or intrinsic metabolic byproducts. In response, cells activate a robust DNA damage response (DDR) network to preserve genomic stability. ...

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