Microbiology and Cell Biology (MCB)
Recent Submissions
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Comparative study of meristem specific functions of the rice transcription factor RFL for vegetative and reproductive development
In model laboratory plant Arabidopsis thaliana, LEAFY (a plant specific transcription factor) is reported to act as a floral organ identity gene. Whereas its ortholog (RFL) in rice, is reported to be involved in regulating ... -
Studies angiospermic root parasite santalum album and its experimental host dolichos lablab
While most of the plants are autotrophic and are the main sustenance of life on this planet, a few plants have acquired the parasitic habit and thrive on other plants. The extent of this dependence varies, and so also the ... -
Studies on the metabolism of ethionamide, a second line antitubercular drug
Ethionamide (2-ethyl, 4-thioisonicotinamido) is an active tuberculostatic second-line drug, which plays an important role in the treatment of pulmonary tuberculosis resistant to one or more of the classical drugs. The drug ... -
Studies on experimental cancer immunosuppressive activity and mechanisms of action of mithramycin
As a first step in evaluating the chemotherapeutic efficacy of mithramycin, an antitumor antibiotic, and correlating its toxic, antitumor, and immunosuppressive properties, the following studies were carried out: The ... -
Some myxobacteria and their activities
Among the fruiting forms, Myxococcus species were more common in soils. They were also comparatively easy to isolate and cultivate. i 20 : Therefore, it was decided to carry out further work on these species. As mentioned ... -
Studies on areca catechulinn with special ref to ganooerma lucidum : a fungal pathogen of area palm
The fungus Ganoderma lucidum is one of the common pathogens of a number of tropical palms such as coconut, arecanut etc. Although the pathogenicity of the fungus on a wide range of hosts has been recorded, there are ... -
Functional characterization of S cerevisiae splicing factor Ycr063w/Bud 31- Insights into its context dependent functions and biochemical interactions with the spliceosome
Regulated gene expression in eukaryotes is a complex, multi-layered process. A critically regulated step is pre-mRNA splicing, essential for the synthesis of functional transcripts. Splicing is carried out by the spliceosome, ... -
Characterization of the high Level expression phenotype of the cell Line PCX5 and Studies on the Regulation of rotaviralgene expression in mammalian cells
Part I - PCX5 Cell Line and High-Level Gene Expression PCX5, a cell line accidentally generated from the prostate cancer cell line PC3BM, showed high-level expression of PDGF-B and reporter genes ( -gal and GFP) compared ... -
Molecular mechanisms of silkgland development and compartment specification in the mulberry silkroom, bombyx mori
The mulberry silkworm, Bombyx mori, is an emerging model system for studies on genetics of quantitative traits, transcriptional regulation, molecular endocrinology, and development (Willis et al., 1995). It is a holometabolous ... -
Bombyx mori nucleopolyhedrovirus : Biotechnological applications and a model to study host-virus interactions
Bombyx mori Nucleopolyhedrovirus: Biotechnological Applications and a Model to Study Host-Virus Interactions Abstract and Synopsis Introduction Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV) can ... -
Mechanistic studies on uracil DNA glycosylases from escherichia coli and mycobacteria : Interaction with uracil containing DNA, Single Stranded DNA Binding protiens(SSBs) and an Inhibitor protein(Ugi)
Mutational and Biochemical Analyses of Uracil-DNA Glycosylase (UDG), Single-Stranded DNA Binding Proteins (SSB), and Ugi Abstract and Synopsis Introduction Uracils arise in DNA either by spontaneous deamination of cytosine ... -
Bombyx mori nucleopolyhedrovirus : Characterization of Late Gene Expression factors,lef4 and p47
Characterization of Late Gene Expression Factors LEF4 and P47 in Bombyx mori Nucleopolyhedrovirus (BmNPV) Abstract and Synopsis Introduction A recurrent threat to the sericulture industry is the infestation of colonies ... -
Characterisation of new restriction endonucleases and molecular interaction studies with Kpnl restriction-modification system
Characterization of New Restriction Endonucleases and Molecular Interaction Studies with the KpnI Restriction-Modification System Abstract and Synopsis Introduction Type II restriction-modification (R-M) systems are the ... -
Human immune responses to the non-structural protein 3(NS3)and the envelope glycoprotein of Japanese encephalitis virus : interferon gamma and perforin production by NS3-specfic T cells correlate with protective immunity
Immune Correlates of Protection and Diagnostic Antigen Development in Japanese Encephalitis Virus (JEV) Abstract and Synopsis Introduction The flavivirus Japanese encephalitis virus (JEV) is the leading cause of viral ... -
Transcription regulation and termination in mycobacteria : DNA gyrase genes as a paradigm
Molecular Biology of Mycobacterium tuberculosis: Transcriptional Regulation and DNA Gyrase Function Abstract and Synopsis Introduction The textbook definition of prokaryotic molecular biology is largely based on experiments ... -
Immunological memory through idiotypic network : A role for B Lymphocytes
Immunological Memory Through Idiotypic Network: A Role for B Lymphocytes Introduction The two defining features of vertebrate immune responses-antigen specificity and memory-have been recognized for centuries. Immunological ... -
Mapping of interacting domains of rinderpest virus nucleaocapsid protein and phospoprotein involved in transcription and Replication
Mapping of Interacting Domains of Rinderpest Virus Nucleocapsid Protein and Phosphoprotein Involved in Transcription and Replication Introduction Rinderpest is a highly contagious disease of cattle and wild bovids, with ... -
Virulence-Associated factors of shigella flexneri 2a : Identification and Characterization
The causative agents of bacillary dysentery, a devastating form of diarrhea, are different species of Shigella and, less frequently, the closely related enteropathogen, enteroinvasive Escherichia coli (EIEC). Also referred ... -
Immune responses in cattle & goats to recombinant hemagglutinin/hemagglutinin-Neuraminidase proteins of rinderpest & peste des petits ruminants viruses-presented as virus like particles
Thesis submitted for the degree of Doctor of Philosophy Indian Institute of Science, Bangalore, India Title: Immune Responses in Cattle and Goats to Recombinant Hemagglutinin/Hemagglutinin-Neuraminidase Proteins of ...
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