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    Browsing Microbiology and Cell Biology (MCB) by Title

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      • Altering DNA topology in mycobacteria: impact of perturbation of DNA gyrase on physiology and gene expression 

        Guha, Sarmistha
        In the current dissertation, efforts have been made to probe the in vivo role of DNA gyrase to determine its importance in the growth, physiology and gene expression in mycobacteria. In this dissertation, the role of DNA ...
      • Alternate Fates of tRNAs in Initiation and Elongation 

        Govindan, Ashwin
        Protein synthesis in all organisms utilizes a special tRNA called the initiator tRNA. Initiator tRNAs take part in the initiation step of protein synthesis by their direct binding to the P‐site of the ribosome. The other ...
      • Analysis Of Interferon y-mediated Cell Cycle Arrest In Human Cancer Cells - Re-examination Of The Involvement Of Cyclin Dependent Kinase 2 

        Vashistha, Surabhi (2011-05-05)
      • Anticancer Drug-Induced Apoptosis Characterisation, Comparative Study And Rescue In Human Leukemic Cell Lines 

        Sondarva, Gautam V (2011-12-12)
      • Antimicrobial Peptides And Salmonella Pathogenesis 

        Vidya Devi, * (2011-02-07)
        Chapter-I Introduction The bacteria known as Salmonellae are gram-negative, rod-shaped intracellular pathogenic bacilli that belong to the family Enterobacteriacea and causes typhoid fever. Enteric fever or typhoid ...
      • Biochemical, Genetic and Molecular characterization of TCP3 and TCP4 transcription factors in Arabidopsis thaliana 

        Sunkara, Preethi
        The TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORs (TCP) family of proteins consists of plant-specific, non-canonical basic helix-loop-helix transcription factors that perform diverse developmental processes. ...
      • Bombyx Mori Nuclear Polyhedrosis Virus : Molecular Biology And Biotechnology Applications 

        Palhan, Vikas B (2012-03-30)
      • Bone Morphogenesis Protein (BMP) Signaling at the Cross-roads of Host-Pathogen Interactions : Implications for Pathogenesis 

        Mahadik, Kasturi Suryakant (2018-06-13)
        Study of cell signalling pathways affected by pathogen entry comprises a fundamental aspect of understanding host-pathogen interactions. In this respect, the current study attempted to ascribe novel roles to Bone Morphogenesis ...
      • Breast Cancer Susceptibility Gene 1 (BRCA1) And Breast Cancer 

        Lakhotia, Smita (2009-04-15)
        Breast Cancer susceptibility gene 1 (BRCA1) & Breast Cancer Breast cancer is one of the most common malignancies affecting women worldwide. About 5-10% of all cases are estimated to be familial. Mutations in the BRCA1 ...
      • Carbon Starvation Genes Mediate the Cross-talk Between Metabolism and Pathogenesis of Salmonella Typhimurium 

        Garai, Preeti
        Carbon starvation genes mediate the cross-talk between metabolism and pathogenesis of Salmonella Typhimurium Salmonella enterica serovar Typhimurium (S. Typhimurium) can infect a wide range of host animals to cause diseases ...
      • Cell Survival Strategies : Role Of Gyrase Modulatory Proteins 

        Sengupta, Sugopa (2010-07-21)
        A steady state level of negative supercoiling is essential for chromosome condensation, initiation of replication and subsequent elongation step. DNA gyrase, found in every eubacteria, serves the essential housekeeping ...
      • Cellular and Molecular Features of the Response of Mycobacterium smegmatis to Rifampicin and Moxifloxacin Upon Prolonged Exposure 

        Sharmada, S
        Bacterial persisters are a subpopulation of bacteria that can tolerate lethal concentrations of antibiotics. These are phenotypic variants that can give rise to drug‐susceptible population upon withdrawal of the antibiotic. ...
      • Characterization Of A Bovine Rotavirus From Humans And Studies On The Structural And Biological Properties Of Rotaviral Enterotoxigenic Nonstructural Protein 4 

        Jagannath, M R (2013-08-14)
      • Characterization Of A Novel Genotype Rotavirus And Investigations On Signalling Pathways In Rotavirus Infected MA104 Cells 

        Reddy, Yugandhar B S (2013-08-14)
      • Characterization of an In Vitro Transcription System for Peste Des Petits Ruminants Virus and Functional Characterization of RNA Triphosphatase Activity of RNA Dependent RNA Polymerase Protein L 

        Ansari, Mohammad Yunus (2018-03-03)
        Peste des petits ruminants virus (PPRV) belongs to the family paramyxoviridae which comprises non segmented negative sense RNA viruses including measles and rinderpest virus. PPRV is the causative agent of peste des petits ...
      • Characterization of Host Protein Interactions with HCV RNA : Implications in Viral Translation, Replication and Design of Antivirals 

        Bhat, Prasanna (2018-05-09)
        HCV genome is a positive sense single-stranded RNA containing a single open reading frame (ORF) flanked by untranslated regions (UTRs), 5’UTR and 3’UTR.Initiation of HCV RNA translation is mediated by internal ribosome ...
      • Characterization of the Cis and Trans Acting Factors that Influence p53 IRES Function 

        Arandkar, Sharath Chandra (2018-03-07)
        p53 is a nodal tumor suppressor protein that acts as a major defense against cancers. Approximately 50% of human tumours have mutations in p53 gene. Among its myriad features, the most distinctive is the ability to elicit ...
      • Characterization of the transsulfuration enzyme Cystathionine beta-synthase as a novel regulatory node in the sulfur metabolism of Mycobacterium tuberculosis 

        Bandyopadhyay, Parijat
        Methionine and cysteine metabolisms are important for the survival and pathogenesis of Mycobacterium tuberculosis (Mtb). The transsulfuration pathway converts methionine to cysteine and represents an important link between ...
      • Deciphering Functions & Interactions of Fission Yeast Splicing Factor SpSlu7 Relevant to Constitutive & Alternative Splicing 

        Sen, Titash
        The fission yeast genome with abundant multi-intronic transcripts, degenerate splice signals and presence of alternative splicing machinery is an attractive unicellular fungal model to investigate splice-site recognition ...
      • Deciphering the mechanisms employed by Salmonella to mediate modulation of host endo-lysosomal machinery 

        Chatterjee, Ritika
        Salmonella genus encompasses Gram-negative, rod-shaped, facultative anaerobic, non-sporulating, and predominantly motile enteric bacteria. It causes pathogenesis in a wide array of hosts, from cold-blooded animals to humans ...

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