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    • Microbiology and Cell Biology (MCB)
    • Browsing Microbiology and Cell Biology (MCB) by Title
    •   etd@IISc
    • Division of Biological Sciences
    • Microbiology and Cell Biology (MCB)
    • Browsing Microbiology and Cell Biology (MCB) by Title
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    Browsing Microbiology and Cell Biology (MCB) by Title

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      • New Active Site Fold And The Role Of Metal Ions In Structure Function Relationship Of A Promiscuous Endonuclease - R.KpnI 

        Saravanan, M (2010-07-08)
        Bacteria employ survival strategies to protect themselves against foreign invaders, including bacteriophages. The ‘immune system’ of bacteria relies mostly on restriction-modification (R-M) systems. The primary role of R-M ...
      • Notch1-Induced Survival Signaling And Its Implications In Cancer Therapeutics 

        Mungamuri, Sathish Kumar (2009-04-15)
        Notch receptors and ligands are type I transmembrane proteins that regulate development and differentiation during cell-cell contact. There are four Notch receptor homologues and five notch ligands, identified in humans ...
      • A Novel Antigen From Mycobacterium Bovis BCG : Biochemical And Immunological Studies 

        Pawar, Santosh N (2011-12-12)
      • Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions 

        Ghosh, Soumitra
        Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, ...
      • Panoramic View of RNA Binding Proteins (RBPs) in Glioblastoma : IMP3, an RBP, is Essential for Glioma Stem-like Cell Maintenance 

        Bhargava, Shruti
        Gliomas are primary brain tumors in adults that are believed to originate from different types of glial cells. Central nervous system gliomas pose particularly difficult problems because of their tendency towards malignancy, ...
      • Perpetuation Of T cell Memory : A Role For Anti-Idiotypic T Cells 

        Lal, Girdhari (2013-08-13)
      • Physiological Importance Of DNA Repair In Mycobacteria 

        Kurthkoti, Krishna (2013-01-16)
      • Physiological Role of Arr, an ADP-ribosyltransferase in Mycobacterium smegmatis 

        Agrawal, Priyanka
        The studies reported in this thesis address the physiological role of an antibiotic resistance gene arr, followed by establishment of the arr knockout strains (generated during the investigation) for drug testing and ...
      • Physiological Role of Folate Dehydrogenase in One Carbon Metabolism of Escherichia Coli 

        Aluri, Srinivas (2018-06-08)
        Thesis addresses the physiological role of formyl tetrahydrofolate synthetase (Fhs) and bifunctional folate dehydrogenase (FolD) in folate mediated one carbon metabolism in bacteria. Thesis consists of 5 chapters. First ...
      • Physiological significance of tRNA sequences and modifications in regulation of the bacterial growth 

        Sahu, Amit Kumar
        Transfer RNA or tRNA is one of the vital components of translation machinery where it acts as an adaptor molecule to bring amino acid to the ribosome in response to the genetic code in mRNA. Its key role is to decode the ...
      • Post translational modification and DNA binding studies with two nucleoid associated proteins of Mycobacterium tuberculosis 

        Anand, Chinmay
        Genome in prokaryotes is found in a small confinement called nucleoid. The nucleoid compaction is brought about by the combined action of topoisomerases and Nucleoid associated proteins (NAPs). Topoisomerases maintain ...
      • PP2A-phosphatase and Polo-like kinase 1 regulates spindle positioning by orchestrating the cortical levels of the dynein adaptor NuMA 

        Keshri, Riya
        The mitotic spindle is a microtubule-based diamond shape structure that captures chromosomes and facilitates their segregation during anaphase. Proper positioning of the mitotic spindle is critical for defining the ...
      • Probing the Splicing and Enzymatic Function of Fission Yeast Prp16 – A DEAD Box RNA Helicase 

        Sharma, Amit Kumar
        Nuclear pre-mRNA splicing occurs at precisely conserved sequence elements at and around the splice sites which result in ligation of exons and release of intron as lariat. The Schizosaccharomyces pombe genome is an apt ...
      • Proliferating Cell Nuclear Antigen From The Mulberry Silkworm Bombyx mori : Cloning And Characterisation 

        Udupa, S Rajesh (2011-12-12)
      • Proteomic Approaches to Study Glioma Development, Progression and Therapy 

        Mohan Kumar, D (2018-04-02)
        Astrocytoma, the tumor of astrocytic origin, accounts for about 60 % of the primary brain tumors. As per World Health Organization grading system, astrocytoma is classified as circumscribed astrocytoma (Grade I; pilocytic ...
      • Proteomics-based Identification of Serum Biomarkers : Role of Secreted MCSF and CRP in Glioma Pathogenesis 

        Mamatha, B N
        Gliomas are the neoplasia of glial cells present in the brain and comprises of more than 70% of all the neoplasms of the central nervous system. They consist of a family of primary brain tumors that are categorized based ...
      • Purification, Characterisation And Regulation Of Nitrite Reductase From Candida Utilis 

        Sengupta, Sagar (2012-06-04)
      • Racemases in Salmonella : Insights into the Dexterity of the Pathogen 

        Iyer, Namrata (2018-02-27)
        Chapter -I Introduction Salmonella is a pathogen well-known for its ability to infect a wide variety of hosts and causes disease ranging from mild gastroenteritis to typhoid fever. During infection, it is exposed to a ...
      • Regulated Expression Of OsMADS1, A MADS Domain Containing Transcription Factor, Involved In Rice Floret Development 

        Kartha, Reena V (2013-08-13)
      • Regulation and Characterization of Transcription Factor Activator Protein-2 Alpha (AP-2α) 

        Nama, Srikanth (2018-02-11)
        Introduction AP2α is a 52 kDa retinoic acid inducible and developmentally regulated activator of transcription, which binds to the DNA in a sequence-specific manner. Transcription factor AP-2α was isolated from HeLa cells ...

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