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    • Browsing Microbiology and Cell Biology (MCB) by Title
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    • Division of Biological Sciences
    • Microbiology and Cell Biology (MCB)
    • Browsing Microbiology and Cell Biology (MCB) by Title
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    Browsing Microbiology and Cell Biology (MCB) by Title

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      • Carbon Starvation Genes Mediate the Cross-talk Between Metabolism and Pathogenesis of Salmonella Typhimurium 

        Garai, Preeti
        Carbon starvation genes mediate the cross-talk between metabolism and pathogenesis of Salmonella Typhimurium Salmonella enterica serovar Typhimurium (S. Typhimurium) can infect a wide range of host animals to cause diseases ...
      • Cell Survival Strategies : Role Of Gyrase Modulatory Proteins 

        Sengupta, Sugopa (2010-07-21)
        A steady state level of negative supercoiling is essential for chromosome condensation, initiation of replication and subsequent elongation step. DNA gyrase, found in every eubacteria, serves the essential housekeeping ...
      • Cellular and Molecular Features of the Response of Mycobacterium smegmatis to Rifampicin and Moxifloxacin Upon Prolonged Exposure 

        Sharmada, S
        Bacterial persisters are a subpopulation of bacteria that can tolerate lethal concentrations of antibiotics. These are phenotypic variants that can give rise to drug‐susceptible population upon withdrawal of the antibiotic. ...
      • Characterization Of A Bovine Rotavirus From Humans And Studies On The Structural And Biological Properties Of Rotaviral Enterotoxigenic Nonstructural Protein 4 

        Jagannath, M R (2013-08-14)
      • Characterization Of A Novel Genotype Rotavirus And Investigations On Signalling Pathways In Rotavirus Infected MA104 Cells 

        Reddy, Yugandhar B S (2013-08-14)
      • Characterization of an In Vitro Transcription System for Peste Des Petits Ruminants Virus and Functional Characterization of RNA Triphosphatase Activity of RNA Dependent RNA Polymerase Protein L 

        Ansari, Mohammad Yunus (2018-03-03)
        Peste des petits ruminants virus (PPRV) belongs to the family paramyxoviridae which comprises non segmented negative sense RNA viruses including measles and rinderpest virus. PPRV is the causative agent of peste des petits ...
      • Characterization of Host Protein Interactions with HCV RNA : Implications in Viral Translation, Replication and Design of Antivirals 

        Bhat, Prasanna (2018-05-09)
        HCV genome is a positive sense single-stranded RNA containing a single open reading frame (ORF) flanked by untranslated regions (UTRs), 5’UTR and 3’UTR.Initiation of HCV RNA translation is mediated by internal ribosome ...
      • Characterization of the Cis and Trans Acting Factors that Influence p53 IRES Function 

        Arandkar, Sharath Chandra (2018-03-07)
        p53 is a nodal tumor suppressor protein that acts as a major defense against cancers. Approximately 50% of human tumours have mutations in p53 gene. Among its myriad features, the most distinctive is the ability to elicit ...
      • Characterization of the transsulfuration enzyme Cystathionine beta-synthase as a novel regulatory node in the sulfur metabolism of Mycobacterium tuberculosis 

        Bandyopadhyay, Parijat
        Methionine and cysteine metabolisms are important for the survival and pathogenesis of Mycobacterium tuberculosis (Mtb). The transsulfuration pathway converts methionine to cysteine and represents an important link between ...
      • Characterization of XRN2-mediated microRNA turnover mechanism and its pathophysiological significance in eukaryotes 

        Nalawade, Rohit
        MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that are extensively involved in the posttranscriptional regulation of gene expression in eukaryotes. Comprehensive studies on miRNA expression and function have ...
      • Deciphering canonical and non-canonical role of splicing factor Prp16 in pathogenic yeast C. neoformans 

        Negi, Manendra Singh
        RNA splicing is a ubiquitous process during eukaryotic gene expression, where non-coding introns are removed from primary transcripts to form functional mRNA. This vital process is carried out by the spliceosome, a large ...
      • Deciphering Functions & Interactions of Fission Yeast Splicing Factor SpSlu7 Relevant to Constitutive & Alternative Splicing 

        Sen, Titash
        The fission yeast genome with abundant multi-intronic transcripts, degenerate splice signals and presence of alternative splicing machinery is an attractive unicellular fungal model to investigate splice-site recognition ...
      • Deciphering the mechanism behind the division of the Salmonella containing vacuole (SCV) and the immunomodulation strategy employed by Salmonella Typhimurium 

        Chopra, Umesh
        The genus Salmonella represents flagellated, Gram-negative, rod-shaped anaerobic bacteria which is a leading cause of food-borne illness and causes enteric disease in a wide range of animals. In humans and several warm-blooded ...
      • Deciphering the mechanisms employed by Salmonella to mediate modulation of host endo-lysosomal machinery 

        Chatterjee, Ritika
        Salmonella genus encompasses Gram-negative, rod-shaped, facultative anaerobic, non-sporulating, and predominantly motile enteric bacteria. It causes pathogenesis in a wide array of hosts, from cold-blooded animals to humans ...
      • Deciphering the role of host protein HuR in RNA virus life cycle and pathogenesis: Hepatitis C Virus and SARS-CoV-2 as exemplars. 

        Raheja, Harsha
        Viruses pose a major threat to human health and the ongoing SARS-CoV-2 pandemic proves as the best evidence for that. Historically, RNA viruses have a major potential to cause such pandemics. They utilise RNA binding ...
      • Deciphering the Role of METTL3-Dependent m6A-epitranscriptome in Glioma Stem-like Cells 

        Visvanathan, Abhirami
        The major roadblocks in treatment for GBM are resistance to therapy and recurrence of GBM cells. Regardless of various treatment strategies, the average survival of GBM patients is poor and incidence of recurrence remains ...
      • Deciphering the role of outer membrane porins in the pathogenesis of Salmonella enterica serovar Typhimurium 

        Roy Chowdhury, Atish
        Porins are highly conserved barrel-shaped proteins bound to the bacterial outer membrane and involved in the selective transport of charged molecules across the membrane. They consist of parallel and anti-parallel β sheets ...
      • Deciphering the role of spermidine in Salmonella Typhimurium pathogenesis 

        Vijay Nair, Abhilash
        Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram-negative, facultative anaerobic bacterium. It infects a broad range of hosts, causing symptoms such as gastroenteritis, abdominal pain, inflammatory diarrhoea ...
      • Decoding Epigenetic Regulators in Cancer: Acetylation of HIF2A by Histone Acetyltransferase 1 (HAT1) is essential for executing hypoxia response in glioma 

        Kumar, Naveen
        Gliomas are tumors of the central nervous system arising from glial cells. Based on the origin of the cell type, it can be astrocytoma, oligodendroglioma, and ependymoma. Astrocytoma is the most common type of glioma, ...
      • Delineating the Role of OsMADS1 in Auxin Distribution, Floret Identity and Floret Meristem Determinacy 

        Lhaineikim, Grace (2017-12-02)
        Rice have highly derived florets borne on a short branch called ‘spikelet’ comprised of a pair of rudimentary glumes and sterile lemma (empty glumes) that subtends a single fertile floret. The floral organs consist of a ...

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