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The Influence of Glycerol and Specific Genes on the Asymmetric Cell Division in Mycobacteria
The Influence of Glycerol and Specific Genes
on the Asymmetric Cell Division in Mycobacteria
Submitted by Atul Pradhan (S.R. No. 03-04-00-10-11-14-1-11678)
Background Information: Mycobacteria maintain heterogeneity in ...
Transcriptional Regulation of Fatty Acid Transport by Sirtuin 2
The heart is a highly dynamic organ and under normal physiological conditions, it is heavily dependent on fatty acid oxidation to meet its energy requirements (Abumrad and Goldberg 2016). Fatty acid transport is a crucial ...
Understanding the redox homeostatic mechanisms in Mycobacterium tuberculosis infection
Mycobacterium tuberculosis (Mtb) is an obligate intra-cellular pathogen that causes the disease tuberculosis (TB) in its human hosts. An estimated 1% of the world population is reported to get infected with the disease ...
Identification and Characterisation of a miRNA releasing activity from Caenorhabditis elegans
MicroRNAs (miRNA) are endogenous, small non coding RNAs, which play a prominent role in eukaryotic gene regulation. Perturbations leading to an altered abundance of miRNAs can lead to pathological conditions like neurological ...
Immunological insights into Epidermal Growth Factor Receptor Signaling: Implications for host-pathogen interactions
Infectious diseases account for a large proportion of morbidity and mortality worldwide. The major global efforts lie in effectively enhancing the health span of infected individuals and more importantly, curbing infection ...
Identifying key determinants underlying variable efficacy of BCG substrains against Pulmonary TB.
Protection conferred by BCG vaccine against adult pulmonary TB ranges from 0–80% based on large, well-controlled field trials. This variability is highly significant (P < 0.0001) and is regarded as being indicative of true ...
Elucidating the mechanism of interaction of Salmonella with plants
Salmonella, is an established pathogen of members of the kingdom Animalia. Its principal
species S. enterica serovars Typhi, Paratyphi and Typhimurium can cause various diseases
ranging from typhoid fever to gastroenteritis ...
The Molecular Basis for the Differential Antibiotic Susceptibility of Mycobacterial Subpopulations
Mycobacterial populations have evolved various strategies to withstand diverse stress
conditions in the environment. One among these strategies is maintenance of phenotypic
heterogeneity, in terms of cell morphology, ...
Unraveling the role of cellular phosphatases in lysosome function and storage diseases
Eukaryotic cellular pathways are maintained and coordinated through biomolecule turnover, which includes synthesis, trafficking, degradation of cellular components and their reutilization. The process of biomolecule ...
Malat1 and COP1 mediated host responses orchestrate mycobacterial pathogenesis
Tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), is viewed to be the predominant cause of death arising due to bacterial infection. Further, the emergence of MDR/XDR strains and co-infections has compounded ...