Division of Biological Sciences: Recent submissions
Now showing items 1-20 of 1129
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Control and Co-ordination in Multi-Joint Movements
Our interactions with the world often entail a wide range of multi-jointed movements. We are bestowed with an abundant degree of freedom, that a movement can be achieved by recruiting multiple joints, muscles, and neural ... -
Studies on the action of nbromsuccinimide on Hemoglobin and lysozyne
The above detailed account of the role of various groups in enzyme function amply illustrates the approaches to the study of the structural basis of enzyme action. One particular fact emerges out of the present account. ... -
Studies on the metabolism of aminophenols
Certain o-aminophenols like 3-hydroxykynurenine and 3-hydroxyanthranilic acid are known to be precursors of nicotinic acid as well as of certain phenoxazinone antibiotics and insect pigments. The metabolism of 3-hydroxyanthranilic ... -
Metabolism of naphthalene and methylnaphthalenes in Pseudomonas putida : Elucidation of catabolic pathways and purification and properties of 1,2-Dihydroxynaphthalene dioxygenase
I. Polycyclic aromatic hydrocarbons (PAHs), which include naphthalene and alkyl-substituted naphthalenes, are universal products of combustion of organic matter. The mutagenic and carcinogenic nature of several PAHs makes ... -
Studies on the amino-acid composition and nutritive value of some Indian food stuffs
The thesis entitled “Studies on the Amino Acid Composition and Nutritive Value of Some Indian Foodstuffs” presents the following pieces of research work carried out by the candidate: Standardisation of the microbiological ... -
Studies on the antibiotic principles of garcinia morella and allium sativum
Part I Section A: The preparation, purification and properties of morellin, the active principle of Garcinia morella, have been described. By chromatographic technique on silica gel columns three distinct pigments viz., ... -
Some aspects of the metabolism of mandelic acid by Aspergillus Niger
The two first enzymes in the pathway for the metabolism of mandelic acid by Aspergillus niger, namely D(-)-mandelate oxidase and L(+)-mandelate oxidase, which respectively catalyze the oxidation of the two enantiomers of ... -
Behavioural and neural signatures of interactions between conflicting emotion and reward
Reward-related events seldom occur in isolation in our everyday lives — a component of emotion processing remains intertwined in many cases. For instance, individuals often work under hostile conditions for higher pay or ... -
Molecular dissection of Komagataella phaffii Rtg1–RtgX function and development of a glutamate-responsive protein expression platform
In Saccharomyces cerevisiae, the basic helix-loop-helix leucine zipper (bHLH-LZ) proteins Rtg1 and Rtg3 form a heterodimeric transcription factor complex that mediates the retrograde response. In Candida albicans, these ... -
Circuit mechanisms of itch modulation: from physiology to pathology
Itch is a distinct somatosensation, evoked by chemical and mechanical pruritogens or psychosomatic factors. It detects harmful sensory stimuli and triggers scratching to remove irritants from the skin. However, chronic ... -
Studying induced and evoked oscillations for probing visual and auditory circuit mechanisms
Specialized sensory regions process incoming sensory inputs using a variety of mechanisms, such as normalization and excitatory-inhibitory interactions. These mechanisms can be studied through induced and evoked oscillations, ... -
Biomechanical and biochemical regulation by the extracellular matrix of breast cancer migration
Although under active investigation, alterations within the microenvironment that are causative to, and a consequence of, tumor progression are only beginning to be better appreciated through advances in imaging, experimental, ... -
Role of PARP16 in Cardiac Remodeling
Role of PARP16 in cardiac remodeling Cardiac remodeling, a complex process involving alterations in myocardial structure and function, is a major contributor to heart failure. While physiological remodeling supports cardiac ... -
Regulation of the Expression of Ribosomal Proteins by Small Downstream ORFs
Eukaryotic mRNAs have historically been believed to harbour a single open reading frame (ORF). However, over the last decade, ribosome profiling has revealed extensive ribosome occupancy in the untranslated regions ... -
An expedition through local and global features of intrinsically disordered proteins using computational lenses
The traditional view in Structural Biology centered on the “one sequence–one structure–one function” paradigm, which emphasized a unique, folded state of protein as the basis for its biological activity. However, this ...