Division of Biological Sciences: Recent submissions
Now showing items 21-40 of 1176
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Conformational studies on peptides containing alpha aminoisobutyric acid and polypeptides with alternating LD-Sequences
The results of semiempirical energy calculations on poly(Aib), varying ACO and ?(NC?C) separately and simultaneously, suggest a novel fourfold helical structure as an energetically favourable model for poly(Aib). This novel ... -
Conformational analysis of cyclic peptides containing Cis peptide units
The dimensions of the cis peptide unit obtained as an average from the three sets of data viz., cyclic di-, higher, and tripeptides are summarized in Table 2.11. On a close examination of the Table, the following salient ... -
RNA granules and DNA damage: Exploring the role of posttranscriptional gene control upon genotoxic stress
Cells constantly encounter genotoxic stress arising from extrinsic environmental factors or intrinsic metabolic byproducts. In response, cells activate a robust DNA damage response (DDR) network to preserve genomic stability. ... -
Studies on chemical modifications of enzymes with O-Benzoquinone. A new reaction of the Quinone with Methionine
The thesis deals mainly with studies on a new reaction of o-benzoquinone with methionine. o-Benzoquinone is a highly reactive compound which takes part in many complex reactions with proteins. Some of the functional groups ... -
Physico-chemical studies on hen's egg yolk lipovitellins and very low density lipoprotiens
The work described in this thesis can be broadly classified into two major sections namely, (1) Chemical studies, which describes the preparation of lipovitellins, fractionation of their protein components and comparison ... -
Studies on vitamin carrier proteins: physicochemical and functional aspects
STUDIES ON VITAMIN CARRIER PROTEINS: PHYSICOCHEMICAL AND FUNCTIONAL ASPECTS submitted by P.B. SESHAGIRI for the award of Ph.D. degree of the Indian Institute of Science, Bangalore, India. Investigations detailed in this ... -
Bacterial transformation of nitroaromatic compounds and its implicatins in detoxification
Nitroaromatic compounds form a major group of environmental pollutants because of their high toxicity, widespread use, and recalcitrance to microbial degradation. The studies incorporated in this thesis aimed at understanding ... -
Effect of 2-methyl-4-dimethly aminoazobenzene on mithchondrial function and turnover
Abstract not available -
Studies on vitamin carrier protiens hormonal induction and modulation of ribflavin carrier protien and retinol
STUDIES ON VITAMIN CARRIER PROTEINS: HORMONAL INDUCTION AND MODULATION OF RIBOFLAVIN CARRIER PROTEIN AND RETINOL BINDING PROTEIN IN IMMATURE CHICKS submitted by B. Durga Kumari for the award of the degree of Doctor of ... -
Studies on the metabolism of riboflavin nucleotide coenzymes in plants
A survey of literature indicates that although the occurrence of B-vitamins in higher plants is well known and also that several plant enzymes require the presence of these for their action, very little work has been carried ... -
Metabolism of phenolic acids in relation to the biosynthesis of ubiquinone and sterols
Abstract not available -
Structural and mechanistic studies on RNase J paralogs and associated multi-enzyme complexes in Staphylococcus aureus
The Staphylococcus aureus RNome, which includes both coding and non-coding RNAs, has a direct bearing on the virulence of this pathogen as it influences the ability to adapt to diverse environments within the host. Multiple ... -
Conformational and Dynamic Motifs in the Biomolecular Recognition of Glycan and Acetyl Functionalities
Biomolecular recognition is a fundamental principle underlying all cellular processes, driven by specific and tightly regulated interactions. This thesis explores the structural basis of recognition mechanisms in two ... -
Physiological Significance of Stop Codon Readthrough
Regulation of translation, the process by which ribosomes synthesize proteins from mRNAs, is critical to maintain cellular proteostasis. Dysregulation of translation is implicated in several neurodegenerative, metabolic, ... -
Lectin from mimosa invisa L and its role in rhizobium recognition
Understanding the specificity of the legume-Rhizobium symbiosis may help in improving biological nitrogen fixation in several ways. The causes for this specificity have been studied in only a few systems like clover, ... -
Studies on the mode of inhibition of avian myeloblastosis virus multipulication by cupric isonicotinic acid hydrazide complex
The primary objectives of cancer chemotherapy programs include the screening and evaluation of new chemicals and natural products in experimental systems for their anticancer activity and the recommendation of new anticancer ...