Division of Biological Sciences: Recent submissions
Now showing items 41-60 of 1176
-
Conformational studies on polynuc leotides and nucleic acids
After an introduction to the nucleic acids and the conformational studies on them at the monomeric and polymeric levels, the need for investigations on the conformations of 3?-nucleotides is outlined. The significance of ... -
Studies on O-H-O Hydrogen Bonds and conformation of cyclic hexa depsipeptides
The working criteria which have been developed for both O-H...O and N-H...O types of hydrogen bond can be utilised. FIG. 3.5. FLOW CHART OF THE PROGRAM MODULE Read input data: (a) coordinates of the hydrogen bond forming ... -
Motifs in proteins: Disulfide constraints and their applications to protein engineering and peptide modelling
By carrying out a detailed data analysis of 175 PP motifs in proteins, sequence–structure relationships were identified for linking loops 1–5 residues long. Conformational families were recognized in 1-, 2-, 3-, and 4-residue ... -
X-ray crystallagraphic studies on the effect of chirality in amino acids aggregation
A programme of systematic X-ray studies on crystalline complexes involving amino acids and peptides is currently under way in this laboratory. These studies, apart from providing a wealth of information on non-covalent ... -
Theoretical studies on peptide conformation
It is now well established that the biological activities of polypeptides and proteins are intimately connected with their 3-dimensional structures and so the determinations of these provide insight into their mode of ... -
Theoretical studies on the influence of exo-anomeric effect,geometry of sugar linkage on the unperturbed dimensions of polysaccharides
Recently, application of conformational energy calculations in the field of carbohydrates has led to a number of interesting and important results. A few attempts have also been made to compute the unperturbed dimensions ... -
Enhancing Therapeutic Potential of Antimicrobial Peptides by Tuning Backbone Conformation
Full text embargo up to Dec 31, 2026 The work reported in this thesis involves tuning the backbone conformation of b-hairpin AMPs to reduce their cytotoxicity, which is determined in terms of reduced hemolytic activity, ... -
Control and Co-ordination in Multi-Joint Movements
Our interactions with the world often entail a wide range of multi-jointed movements. We are bestowed with an abundant degree of freedom, that a movement can be achieved by recruiting multiple joints, muscles, and neural ... -
Behavioural and neural signatures of interactions between conflicting emotion and reward
Reward-related events seldom occur in isolation in our everyday lives — a component of emotion processing remains intertwined in many cases. For instance, individuals often work under hostile conditions for higher pay or ... -
Studies on the metabolism of aminophenols
Certain o-aminophenols like 3-hydroxykynurenine and 3-hydroxyanthranilic acid are known to be precursors of nicotinic acid as well as of certain phenoxazinone antibiotics and insect pigments. The metabolism of 3-hydroxyanthranilic ... -
Studies on the action of nbromsuccinimide on Hemoglobin and lysozyne
The above detailed account of the role of various groups in enzyme function amply illustrates the approaches to the study of the structural basis of enzyme action. One particular fact emerges out of the present account. ... -
Studies on the amino-acid composition and nutritive value of some Indian food stuffs
The thesis entitled “Studies on the Amino Acid Composition and Nutritive Value of Some Indian Foodstuffs” presents the following pieces of research work carried out by the candidate: Standardisation of the microbiological ... -
Metabolism of naphthalene and methylnaphthalenes in Pseudomonas putida : Elucidation of catabolic pathways and purification and properties of 1,2-Dihydroxynaphthalene dioxygenase
I. Polycyclic aromatic hydrocarbons (PAHs), which include naphthalene and alkyl-substituted naphthalenes, are universal products of combustion of organic matter. The mutagenic and carcinogenic nature of several PAHs makes ... -
Studies on the antibiotic principles of garcinia morella and allium sativum
Part I Section A: The preparation, purification and properties of morellin, the active principle of Garcinia morella, have been described. By chromatographic technique on silica gel columns three distinct pigments viz., ... -
Some aspects of the metabolism of mandelic acid by Aspergillus Niger
The two first enzymes in the pathway for the metabolism of mandelic acid by Aspergillus niger, namely D(-)-mandelate oxidase and L(+)-mandelate oxidase, which respectively catalyze the oxidation of the two enantiomers of ...