Division of Biological Sciences: Recent submissions
Now showing items 1-20 of 1186
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Studies on the irreversible thermal denaturation of Rnase A
“STUDIES ON THE IRREVERSIBLE THERMAL DENATURATION OF RIBONUCLEASE A” SUBMITTED BY GIRISH SAHNI FOR THE Ph.D. DEGREE OF THE INDIAN INSTITUTE OF SCIENCE, BANGALORE–560012, INDIA** Processes whereby proteins and enzymes are ... -
Matabolism of phenylacetic acid by aspergillus niger
The metabolism of phenylacetic acid by Aspergillus niger was studied. The culture filtrates of A. niger grown on phenylacetate for 40 hours exhibited the presence of 2? and 3?hydroxyphenylacetic acids, 3?hydroxybenzyl ... -
Some aspects of the metabolism of mandelic acid by pseudomonas convexa, Ph.D. Thesis
The metabolism of mandelic acid (phenylglycolic acid) has been studied in detail in several bacteria, and it has been shown that the side chain of mandelic acid is first degraded, resulting in the formation of benzoic acid, ... -
Structural features of the initial active intermediate formed during acid denaturation of bovine pancreatic ribonuclease-A, Ph.D. Thesis
The present thesis deals with structural investigations of the initial products formed during acid denaturation of ribonuclease A. We have divided our observations into two sections. Section I The nature of the deamidation ... -
Indoeacetaldoxime hydro-lyase of gibberella fujikoroi
In the following pages, the work described in the preceding chapters has been summarized. The conversion of IAOX to IAN was shown to be an enzymatic process. Culture conditions for the growth of Gibberella fujikuroi ... -
Influence of vitamin B12 on the nutritive value of vegetable proteins
The work reported in this thesis relates to two main aspects: (a) To confirm and extend the finding that vitamin B?? counteracts the adverse effects of the tryptic and growth inhibitors present in raw soyabean. (b) To ... -
Characterizing the viral factors and host determinants that control Dengue virus infection and pathogenesis
Background – Dengue virus is a mosquito-borne flavivirus that is the causative agent for dengue fever, which progresses to dengue shock syndrome in many patients. It is estimated that around 390 million dengue infections ... -
Unraveling the layers of DNA with the DNA-PAINT brush
DNA is both the repository of genetic information and a versatile nanoscale material whose stability and function are governed by base pairing and base-stacking interactions. Despite their fundamental role in DNA structure, ... -
Studies on the roles of Lon protease and its substrates during antibiotic resistance in Escherichia coli: modulatory effects of nitroaromatics and nitrofurantoin
Bacteria adapt to environmental stresses, including antibiotic stress, by regulating various genes and metabolic pathways. In prokaryotes, the energy-dependent protein degradation is controlled primarily by two ... -
Patterns and drivers of elevational migration in Himalayan birds
Migration is a behavioural strategy that species use to deal with seasonal variation in climate and resources. A common form of migration is elevational migration, which is a short-distance movement undertaken by mountain ... -
Decoding determinants of selectivity in biomolecules
Molecular events demonstrate remarkable specificity amid complexity in its cellular environment. This phenomenon, termed biomolecular recognition, is fundamental to the organization and regulation of biological systems. ... -
PSD95 as a biophysical modulator of synaptic communication
PSD95 is a core scaffold protein of the postsynaptic density (PSD) at excitatory synapses and a member of the MAGUK family, where it plays a central role in organizing glutamate receptors, ion channels, and signalling ... -
Role of Queuosine in Codon-Anticodon Interaction
The speed and accuracy of the process of protein synthesis is very high. The major step at which the fidelity of translation is governed is at the step of codon?anticodon pairing. An erroneous codon?anticodon pairing can ... -
Purification and characterization of DNA-dependent RNA polymerase II from candida utilis
Abstract not available -
Importance of formylation in eubacterial translation initiation
Initiation of protein synthesis in all organisms occurs with the amino acid methionine. In the case of eubacteria and eukaryotic organelles, methionine is further modified to formylmethionine by the enzyme methionyl?tRNA ...