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    Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions 

    Ghosh, Soumitra
    Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, ...

    Exploration of the Recombination Repair Pathway in Mycobacteria : Identification and Characterization of New Proteins 

    Singh, Amandeep
    Genomic integrity is a fundamental requisite for survival and proliferation of all organisms. The genetic material is continuously threatened by a multitude of extrinsic and intrinsic factors. Consequently, the presence ...

    Regulation of Host Innate Immune Responses by Hippo Signaling Pathway during Pattern Recognition Receptors (PRRs) Driven Inflammation : Implication for Host-Pathogen Interactions 

    Boro, Monoranjan
    Innate immunity refers to the first line of defence system of the host that comes into play immediately or within hours of appearance of invading pathogens like bacteria, viruses and fungi. Cells of the innate immune system ...

    Wnt/β-Catenin-dependent Epigenetic Factors Shape Host Immune Responses During Mycobacterial Infection 

    Prakhar, Praveen
    The genus mycobacterium has more than 120 species of bacteria; one being M. tuberculosis (Mtb), the etiological agent of tuberculosis (TB). During infection, the host mounts a heightened immune response to contain the ...

    Insights into the Regulation of Transcription Initiation of DNA Gyrase and Role of Transcription Factor Gre from Mycobacterium tuberculosis 

    Jha, Rajiv Kumar
    Genus Mycobacterium comprises a large number of species including many pathogens such as Mycobacterium leprae, Mycobacterium abscessus and Mycobacterium tuberculosis (Mtb), the last one is the causative agent of the fatal ...

    Response of Mycobacterium tuberculosis to Hypoxia and its physiological Significance - A Morphological and Molecular Level Study 

    Jakkala, Kishor
    Mycobacterium tuberculosis (Mtb) has evolved as an important clinical pathogen due to its ability to gain multidrug resistance, to enter into latency to persist there and to get reactivated from the latent infection in ...

    Malat1 and COP1 mediated host responses orchestrate mycobacterial pathogenesis 

    Bhatt, Bharat
    Tuberculosis, which is caused by Mycobacterium tuberculosis (Mtb), is viewed to be the predominant cause of death arising due to bacterial infection. Further, the emergence of MDR/XDR strains and co-infections has compounded ...

    Structural and Functional Characterization of Enzymes of Proline Biosynthesis Pathway in Mycobacterium tuberculosis 

    Kanika, *
    Tuberculosis is the second largest killer disease on global scale after HIVAIDS. The rapid evolution of Mycobacterium tuberculosis into drug resistant strains and the toxicity of these drugs are the major constraints in ...

    Topoisomerase i from mycobacterium tuberculosis : Dynamics of enzyme function and inhibitor development 

    Godbole, Adwait Anand
    Inside the bacterial cell, the genetic material is maintained in a negatively supercoiled state within a compact space. The supercoiling of the genome undergoes topological perturbations during a variety of cellular processes ...

    Mechanistic insights into protein stabilization and protein-protein interactions 

    Chattopadhyay, Gopinath
    Most amino acid substitutions in a protein either lead to partial loss of function or are near neutral. Several studies have shown the existence of second-site mutations that can rescue the defects caused by diverse loss ...
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    AuthorAgrawal, Ruchi (1)Anand, Chinmay (1)Anand, Praveen (1)Bandyopadhyay, Parijat (1)Banerjee, Arka (1)Bansal, Kushagra (1)Basu Roy, Tanaya (1)Behera, Debashree (1)Bharti, Sanjay Kumar (1)Bhatt, Bharat (1)... View MoreSubject
    Mycobacterium tuberculosis (44)
    NATURAL SCIENCES (20)M. tuberculosis (8)Mycobacteria (8)Biochemistry (7)Microbiology and Cell Biology (7)DNA Repair (4)Bacterial Nucleoid (3)Escherichia coli (3)tuberculosis (3)... View MoreDate Issued2010 - 2018 (13)2005 - 2009 (1)Has File(s)Yes (43)No (1)

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