Browsing Division of Biological Sciences by Title
Now showing items 665-684 of 957
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Salmonella Pathogenesis in Dendritic Cells : Stealthy Approach Against Adaptive Immune Response
Synopsis of work done by Mayuri Gogoi (SR No. 10-09-00-10-31-11-1-08534) for the award of Ph.D. degree in the Faculty of Science, Indian Institute of Science, Bangalore, India. Thesis title: Salmonella pathogenesis in ... -
Scanning mutagenesis studies of HIV-1 Env immunogenicity and structure
Human Immunodeficiency Virus type 1 (HIV-1) is the etiological agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a global pandemic with 36.7 million people living with HIV-1 all over the world and approximately ... -
Secondary Structures in Proteins : Identification and Analyses
(2018-07-12)Proteins are large biomolecules consisting of one or more long chains of amino acid residues. They perform a vast array of functions within living organisms. In this thesis, we present analyses of different secondary ... -
Seed Dispersal In The Tropical Dry Forests Of Mudumalai, Southern India
(2011-06-30)Plants depend on a wide variety of vectors, both biotic and abiotic, to move their seeds to locations away from parent plants. The stages between seed production and seedling establishment in the plant life cycle are under ... -
Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution
(2010-09-30)Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ... -
Sensory Ecology Of Acoustic Communication In The Tropical Bushcricket Genus Mecopoda : Mechanisms And Evolution Of Synchrony
(2009-07-10)In this thesis, I characterise five species of the bushcricket genus Mecopoda with respect to their acoustic signals and morphology and investigate the phenomenon of acoustic synchrony in one of these five species: Mecopoda ... -
Sequence Analysis And Design Of Immunogens From The Stem Domain Of Influenza Hemagglutinin
(2013-07-10)Influenza is an important respiratory pathogen that infects several million people each year. Currently available flu vaccines have to be updated regularly in order to be effective as the virus changes its composition by ... -
Sequence And Structural Determinants of Helices in Membrane Proteins
(2017-09-23)Membrane proteins roughly constitute 30% of open reading frames in a genome and form 70% of current drug targets. They are classified as integral, peripheral membrane proteins and polypeptide toxins. α-helices and β -strands ... -
Sexual Selection On Elephant Tusks
(2017-06-12)Darwin was troubled by elaborate male traits observed in many species that are seemingly maladaptive for survival, the peacock’s tail being the most iconic of all. He wrote "The sight of a feather in a peacock’s tail, ... -
Single-channel studies on human TREK-1 (hTREK-1) channels to intracellular ischemia related factors
TREK-1, a member of the two-pore domain family of potassium channels, majorly contributes to the maintenance of resting membrane potential of a cell and has been reported to respond to ischemic levels of intracellular ... -
Small Heat Shock Proteins from Bacteria and a Bacteriophage
Proteins can unfold during heat and other types of stress and tend to aggregate with subsequent loss of function. This event is prevented by small Heat Shock Proteins (sHSPs) acting as molecular chaperones. sHSPs do not ... -
Small Heat Shock Proteins from Oryza Sativa and Salmonella Enterica
(2018-05-09)Small heat shock proteins (sHSPs) are a ubiquitous family of molecular chaperones that play a vital role in maintaining protein homeostasis in cells. They are the first line of defence against the detrimental effects of ... -
Social Organisation And Cooperation In Genetically Mixed Colonies Of The Primitively Eusocial Wasp, Ropalidia Marginata
(Indian Institute of Science, 2005-08-05)Altruism in its extreme form is seen in social insects where most individuals give up their own reproduction and work to rear the offspring of their queen. The origin and evolution of such sterile worker castes remains a ... -
Soil microorganisms and biogeochemical cycles in a grazing ecosystem: interactions between producers, consumers, and decomposers
Microorganisms are the unseen majority that determines ecosystem processes, they perform biogeochemical functions that translate into essential services, and regulate global climate. In grazing ecosystems, which represent ... -
Solution NMR Studies Of E.Coli Acetohydroxy Acid Synthase (AHAS) I
(2010-04-13)Branched chain amino acids are classified as essential amino acids since their biosynthetic routes or pathways are restricted only to micro-organisms, fungi and plants. Given their unique distribution, the enzymes of the ... -
Solution NMR Studies Of Peptide Toxins From Cone Snails And Scorpion
(2010-09-13)Major constituents of the venom of various animals are peptidogenic in nature. Marine snails belonging to the species Conus are venomous predators that use small, structurally constrained peptides present in their venom ... -
Solution Structural Studies And Substrate Binding Properties Of The Amino-Terminal Domain Of E.coli Pantothenate Synthetase
(2011-03-29)Pantothenate synthetase (PS), which catalyzes the last step in the pantothenate (vitamin B5) biosynthesis, is a dimeric enzyme present in bacteria, fungi and plants. The enzymatic properties of PS from Escherichia Coli, ... -
Solution Structure Studies on the Effects of Aromatic Interactions and Cross-Strand Disulfide Bonds on Protein Folding
(2018-07-05)The work presented in this thesis focusses primarily on the determination of protein structure at atomic resolution, with NMR spectroscopy as the principle investigative tool. The thesis is divided into four parts. Part I ... -
Solution structures and conformational isomerism of novel conopeptides from Indian marine cone snails
This thesis describes the structure determination of peptides found in marine cone snails’ venom at atomic resolution and their biological activity. Chapter 1 gives a brief introduction to the cone snails, conopeptides, ... -
Solution Structures and Dynamics of Conotoxins and Small MutS Related Domain from Helicobacter Pylori MutS2
(2018-06-08)The work presented in this thesis describes the determination of structures of peptides and proteins at atomic resolution. Nuclear Magnetic Resonance (NMR) spectroscopy was used as the principal method of investigation. ...