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      • (p)ppGpp and c-di-GMP : A Tale of Two Second Messengers in Mycobacterium smegmatis 

        Gupta, Kuldeepkumar Ramnaresh
        Nucleotide based second messengers are known to regulate wide variety of processes in all domains of life. Two such bacterial second messengers are (p)ppGpp (guanosine tetra- or pentaphosphate) and c-di-GMP (cyclic dimeric ...
      • (p)ppGpp and Stress Response : Decoding the Key Pathways by Small Molecule Analogues Biophysical Methods and Mass Spectrometry 

        Syal, Kirtimaan (2018-06-08)
        Under hostile conditions, bacteria elicit stress response. Such stress response is regulated by a secondary messenger called (p)ppGpp. (p)ppGpp is involved in wide range of functions such as GTP homeostasis, biofilm formation ...
      • Panoramic View of RNA Binding Proteins (RBPs) in Glioblastoma : IMP3, an RBP, is Essential for Glioma Stem-like Cell Maintenance 

        Bhargava, Shruti
        Gliomas are primary brain tumors in adults that are believed to originate from different types of glial cells. Central nervous system gliomas pose particularly difficult problems because of their tendency towards malignancy, ...
      • Parietal and prefrontal control of distinct components of attention 

        Banerjee, Sanjana
        In this thesis, we investigate behavioural mechanisms and neural substrates of distinct components of endogenous spatial attention. Endogenous attention facilitates neural processing of the selected stimulus through one ...
      • Pathogen-derived volatiles modulate flight or fight response in Caenorhabditis elegans 

        Prakash, Deep
        In nature, the interaction between two organisms largely relies on their ability to sense and respond to each other, which involves many specific chemicals and signaling pathways. Animals have evolved mechanisms to detect ...
      • Patterns and Drivers of Multimodal Signalling in Diurnal Geckos 

        Kabir, Md Shakilur
        Effective communication in animals comprise emission of a signal by a signaller and a response by a receiver, such that the interaction is beneficial to either only the signaller, or both the signaller and the receiver. ...
      • Peptidase N, A Major Aminopeptidase Belonging To The M1 Family : Biochemical And Functional Implications 

        Anujith Kumar, K V (2009-08-05)
        Intracellular protein degradation is required for maintaining the cellular proteome and regulating cellular processes. This pathway involves proximal ATP-dependent proteases that unfold and translocate proteins targeted ...
      • Peritoneal colonization of ovarian cancer 

        Sarkar, Purba
        The primary cause of mortality associated with cancer is metastasis, i.e., the spread of transformed cells from the site of oncogenesis to secondary loci within the body. Epithelial ovarian cancer (EOC) is a debilitating ...
      • Peroxisomal Targeting Of Pichia Pastoris Cytochrome C During Methanol And Fatty Acid Metabolism 

        Mohanty, Abhishek (2011-03-08)
        Intracellular protein sorting plays a key role in the regulation of cellular metabolism, gene expression, signal transduction and a number of other cellular processes. Proteins targeted to specific cellular compartments ...
      • Perpetuation Of T cell Memory : A Role For Anti-Idiotypic T Cells 

        Lal, Girdhari (2013-08-13)
      • Pharmacological Modulation Of Recombinant Human Two-Pore Domain K+ Channels : Whole-Cell patch-Clamp Analysis 

        Harinath, S (2011-10-21)
        Background potassium currents play an important role in the regulation of the resting membrane potential and excitability of mammalian neurons. Recently cloned two- pore domain potassium channels (K2p) are believed to ...
      • The Phenomenon Of Blastocyst Hatching : Role Of COX-2 And NF-kB 

        Roy, Shubhendu Sen (2014-12-01)
        The zona-pellucida (zona, ZP) is an adhesion-refractory, acellular coat enclosing the rapidly growing, free-living mammalian preimplantation embryo which undergoes successive cleavage divisions to form the blastocyst, ...
      • A Phylogenetic Perspective on The Phytogeography of Western Ghats 

        Divya, B
        I used a finer scale data of 156 published plots across the entire latitudinal range of WG, covering most of the protected forests. The pruned phylogeny for this study consisted of 367 species, of which ~ 50% are taxa endemic ...
      • Phylogeny And Biogeography Of Hemidactylus Oken, 1817 Geckos Of The Indian Subcontinent 

        Bansal, Rohini (2013-02-25)
        Geckos of the genus Hemidactylus Oken, 1817 are one of the most widely distributed and species-rich groups of gekkonids. With approximately 90 species, the genus Hemidactylus accounts for 10% of the total number of species ...
      • Physiological And Exogenous Means of Regulating DNA Damage Response : Insights into Mechanisms of DNA Repair And Genomic Instability 

        Sebastian, Robin (2017-09-23)
        Maintenance of genomic integrity with high fidelity is of prime importance to any organism. An insult which may result in compromised genome integrity is prevented or its consequences are monitored by advanced cellular ...
      • Physiological Importance Of DNA Repair In Mycobacteria 

        Kurthkoti, Krishna (2013-01-16)
      • Physiological Interactions between Neuronal Active Conductances And Inositol Trisphosphate Receptors in Neurons and Astrocytes 

        Ashhad, Sufyan (2018-07-23)
        Intricate interactions among constituent components are defining hallmarks of biological systems and sculpt physiology across different scales spanning gene networks to behavioural repertoires. Whereas interactions among ...
      • Physiological Role of Arr, an ADP-ribosyltransferase in Mycobacterium smegmatis 

        Agrawal, Priyanka
        The studies reported in this thesis address the physiological role of an antibiotic resistance gene arr, followed by establishment of the arr knockout strains (generated during the investigation) for drug testing and ...
      • Physiological Role of Folate Dehydrogenase in One Carbon Metabolism of Escherichia Coli 

        Aluri, Srinivas (2018-06-08)
        Thesis addresses the physiological role of formyl tetrahydrofolate synthetase (Fhs) and bifunctional folate dehydrogenase (FolD) in folate mediated one carbon metabolism in bacteria. Thesis consists of 5 chapters. First ...
      • Physiological significance of tRNA sequences and modifications in regulation of the bacterial growth 

        Sahu, Amit Kumar
        Transfer RNA or tRNA is one of the vital components of translation machinery where it acts as an adaptor molecule to bring amino acid to the ribosome in response to the genetic code in mRNA. Its key role is to decode the ...

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