Browsing Division of Biological Sciences by Title
Now showing items 298-317 of 957
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Habitat Acoustics And Microhabitat Selection In An Ensiferan Assemblage Of A Tropical Evergreen Forest │
(2013-08-29)Several animals, both vertebrate and invertebrate, communicate using sound and they do so in a non-ideal medium, the habitat in which they live. As acoustic signals pass through the habitat, they suffer loss of information ... -
Heat Shock Protein 70 Of Plasmodium Falciparum: Proteomic Analysis Of Its Complexes And Cellular Functions
(Indian Institute Of Science, 2004-10)Hest shock protein 70 (Hsp70) class of chaperones is highly conserved and present ubiquitously in all cellular organisms They play important role in folding of nascent polypeptides and translocation of precursor proteins ... -
Helicobacter Pylori Restriction-Modification Systems : Possible Roles Beyond Genome Protection
(2013-06-06)Helicobacter pylori is one of the most potential and successful human pathogen which colonizes atleast 50% of world population. One of the important characteristics of this pathogen is the degree of allelic diversity and ... -
HIV-1 and SARS-CoV-2 immunogen design
Human Immunodeficiency Virus (HIV-1) is the aetiologic agent of AIDS. Presently there are ~38 million HIV-1 infected individuals worldwide and ~1 million deaths in 2019. Since its discovery, the quest for vaccine candidate ... -
HIV-1 Immunogen Design : Envelope Protein Minimization, Stabilization and Glycan Removal
Effective vaccines exist for a number of viral diseases. However, despite much effort, there is no successful vaccine against the Human Immunodeficiency Virus (HIV-1). The envelope glycoprotein (Env) of HIV-1 gp120, the ... -
Homeostasis of cyclic-di-AMP in Mycobacterium smegmatis: Functional and structural contributions of c-di-AMP synthase (MsDisA) and hydrolase (MsPDE)
In bacteria, cyclic-di-nucleotide based second messengers regulate various physiological processes including the stress response. For the past decades, cyclic diadenosine monophosphate (c-di-AMP) has emerged as a crucial ... -
Hormones and Cuscuta Development Abscisic Acid And Its Conjugates-Endogenous Levels And Metabolism During Growth And Haustoria Formation
(Indian Institute of Science, 2005-04-25)Cuscuta or dodder is one of the best known higher plant parasite with around 158 species over 5 continents parasitising a wide variety of host plants (Yuncker,1932) Dodders are characterised by their interesting parasitic ... -
Host Gene Expression Profiling of Japanese Encephalitis Virus Infected cells : Identification of Novel Pro- and Anti-viral Genes
(2017-11-27)Japanese encephalitis virus (JEV), a mosquito-borne flavivirus is the causative agent of Japanese encephalitis (JE). The disease affects mostly children and around 30000– 50000 cases of JE and up to 15000 deaths are reported ... -
Host Location in Non-pollinating Fig Wasps of Ficus Racemosa : Age, Oviposition History and the Ovipositor
The fig–fig wasp system is a brood site pollination system where pollinators breed inside an enclosed globular inflorescence (syconium) that they pollinate. This pollination mutualism is subjected to exploitation by the ... -
Host responses in Fas-deficient autoimmune-prone lpr mice upon Salmonella Typhimurium infection
Autoimmune diseases can potentially pre-dispose an individual to infections. On the other hand, infections can trigger, exacerbate or ameliorate autoimmunity. Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare genetic ... -
Host-Pathogen Interaction Between Staphylococcus Aureus And Murine Macrophages
(2013-09-04)Chapter 1: Introductionn Staphylococci are gram positive rotund bacteria that grow in clusters; and hence get their name. The genus of Staphylococcus comprises of over 30 species of which S. epidermidis and S.aureus are ... -
Host-Pathogen Interactions in Hepatitis C Virus Infection : Deciphering the Role of Host Proteins and MicroRNAs
(2018-07-19)Host-pathogen interactions in Hepatitis C Virus infection: Deciphering the role of host proteins and microRNAs Hepatitis C virus (HCV) is a positive sense single stranded RNA virus belonging to the Hepacivirus genus of ... -
How Much Initiator tRNA Does Escherichia Coli Need?
(2017-11-27)The work discussed in this thesis deals with the significance of initiator tRNA gene copy number in Escherichia coli. A summary of the relevant literature discussing the process of protein synthesis, ... -
Human Immune Response To Japanese Encephalitis Virus Guides Development Of Vaccines With Long Lasting Immunity
(2013-05-21)Chapter 1: Role of JEV NS1 in protective immunity and in immunopathology. Previous studies from our laboratory revealed T cell immunodominance of non structural proteins NS3 and NS1 during natural JEV infections in humans ... -
Human Spermatogenesis : Differential Gene Expression And Regulation
(2010-08-24)Spermatogenesis is a complex process of male germ cell development in which the diploid spermatogonia undergo series of mitotic divisions and differentiation steps culminating into the preleptotene spermatocytes which then ... -
Identification and Biochemical Characterization of Novel Inhibitors of Nonhomologous End Joining: Implications in DNA Double-Strand Break Repair and Cancer Therapy
To summarize, in the present study, we have synthesized and characterized three novel NHEJ inhibitors targeting DNA Ligase IV, with several fold better efficacy compared to SCR7 and thus potential to be developed as cancer ... -
Identification and Characterisation of a miRNA releasing activity from Caenorhabditis elegans
MicroRNAs (miRNA) are endogenous, small non coding RNAs, which play a prominent role in eukaryotic gene regulation. Perturbations leading to an altered abundance of miRNAs can lead to pathological conditions like neurological ... -
Identification And Characterisation Of Two Silencing Barrier Sequences In Saccharomyces Cerevisiae
(2010-07-21)In eukaryotic cells, genomic DNA exists as chromatin in association with histone octamers called nucleosomes, and various other chromatin proteins. Chromatin structure varies along the chromosome and this influences the ...