Browsing Division of Biological Sciences by Title
Now showing items 602-621 of 1093
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Oleosin, a Bifunctional Enzyme is Phosphoregulated by a Protein Kinase
In eukaryotic cells, lipids are indispensable principal components that vitiate biological life. Lipids are classified into two major groups, polar and non-polar lipids. Polar lipids are phospholipids, whereas non-polar ... -
On mechanisms and conformational dynamics of Drug:H+ Antiporters
Multidrug efflux is an active transport process involving energy consumption to drive antibacterial compounds out of cells. This is performed either through primary active transport, where chemical energy, such as hydrolysis ... -
On Trait Evolution in a Heterogeneous Environment: Oviposition Site Selection in a Mosquito in Response to Multiple Risk Factors
A focus in evolutionary biology is to understand the drivers of diversity in animal behavioural traits in the living world. Animals facing similar problems in the environment, such as the problem of how much to invest in ... -
Optical and behavioural tools to investigate the neural correlates of learning and memory
Events in our everyday life are encoded as memories that can be consciously recollected and remembered, although our ability to retrieve the specific details associated with these events diminish with time. Such losses ... -
Orienting Macromolecule At The Air - Water Interface : DNA-Protein Interaction On Langmuir Films
(2010-07-23)The Langmuir – Blodgett (LB) technique is about forming insoluble monolayer on the surface of aqueous solution and recently, it has emerged as one of the best method to study floating monolayer at the air – water interface. ... -
Oxidative Stress In The Brain: Effects Of Hydroperoxides And Nitric Oxide On Glyceraldehyde 3-Phosphate Dehydrogenase And Phosphoinositide Cycle Enzymes
(Indian Institute of Science, 2005-09-01)In the aerobic cell, oxygen can be converted into a series of reactive metabolites, together called as "reactive oxygen species" (ROS). This large group include both radical and non-radical species such as superoxide anion ... -
(p)ppGpp and c-di-GMP : A Tale of Two Second Messengers in Mycobacterium smegmatis
Nucleotide based second messengers are known to regulate wide variety of processes in all domains of life. Two such bacterial second messengers are (p)ppGpp (guanosine tetra- or pentaphosphate) and c-di-GMP (cyclic dimeric ... -
(p)ppGpp and Stress Response : Decoding the Key Pathways by Small Molecule Analogues Biophysical Methods and Mass Spectrometry
(2018-06-08)Under hostile conditions, bacteria elicit stress response. Such stress response is regulated by a secondary messenger called (p)ppGpp. (p)ppGpp is involved in wide range of functions such as GTP homeostasis, biofilm formation ... -
Panoramic View of RNA Binding Proteins (RBPs) in Glioblastoma : IMP3, an RBP, is Essential for Glioma Stem-like Cell Maintenance
Gliomas are primary brain tumors in adults that are believed to originate from different types of glial cells. Central nervous system gliomas pose particularly difficult problems because of their tendency towards malignancy, ... -
Parietal and prefrontal control of distinct components of attention
In this thesis, we investigate behavioural mechanisms and neural substrates of distinct components of endogenous spatial attention. Endogenous attention facilitates neural processing of the selected stimulus through one ... -
Pathogen-derived volatiles modulate flight or fight response in Caenorhabditis elegans
In nature, the interaction between two organisms largely relies on their ability to sense and respond to each other, which involves many specific chemicals and signaling pathways. Animals have evolved mechanisms to detect ... -
Patterns and Drivers of Multimodal Signalling in Diurnal Geckos
Effective communication in animals comprise emission of a signal by a signaller and a response by a receiver, such that the interaction is beneficial to either only the signaller, or both the signaller and the receiver. ... -
Peptidase N, A Major Aminopeptidase Belonging To The M1 Family : Biochemical And Functional Implications
(2009-08-05)Intracellular protein degradation is required for maintaining the cellular proteome and regulating cellular processes. This pathway involves proximal ATP-dependent proteases that unfold and translocate proteins targeted ... -
Peritoneal colonization of ovarian cancer
The primary cause of mortality associated with cancer is metastasis, i.e., the spread of transformed cells from the site of oncogenesis to secondary loci within the body. Epithelial ovarian cancer (EOC) is a debilitating ... -
Peroxisomal Targeting Of Pichia Pastoris Cytochrome C During Methanol And Fatty Acid Metabolism
(2011-03-08)Intracellular protein sorting plays a key role in the regulation of cellular metabolism, gene expression, signal transduction and a number of other cellular processes. Proteins targeted to specific cellular compartments ... -
Pharmacological Modulation Of Recombinant Human Two-Pore Domain K+ Channels : Whole-Cell patch-Clamp Analysis
(2011-10-21)Background potassium currents play an important role in the regulation of the resting membrane potential and excitability of mammalian neurons. Recently cloned two- pore domain potassium channels (K2p) are believed to ... -
The Phenomenon Of Blastocyst Hatching : Role Of COX-2 And NF-kB
(2014-12-01)The zona-pellucida (zona, ZP) is an adhesion-refractory, acellular coat enclosing the rapidly growing, free-living mammalian preimplantation embryo which undergoes successive cleavage divisions to form the blastocyst, ...