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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title 
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    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title
    •   etd@IISc
    • Division of Biological Sciences
    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title
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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title

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      • Understanding cholesterol homeostasis and its impact on GPCR signalling in aging 

        Asthana, Suramya
        Full text embargo One year up to July 2024 Aging is defined as the time-related deterioration of physiological functions necessary for survival of organisms. Despite significant progress in the extension of human lifespan ...
      • Understanding the role of hydrogen sulfide in regulating redox homeostasis and inflammation during cellular senescence 

        Gupta, Kavya
        Aging involves the time-dependent deterioration of physiological functions, which can be attributed to various factors. Cellular senescence has been shown to be akin to aging, which involves alteration in redox homeostasis ...
      • Unfolding the Mechanism of Notch1 Receptor Activation : Implications in Cancer Stem Cell Targeting 

        Sharma, Ankur (2018-05-01)
        Notch receptors and ligands are single-pass transmembrane proteins which play important roles in cell-cell communication. Notch in ‘harmony’ with other signaling pathways regulate the entire diversity of metazoan life ...
      • Unraveling the Mechanism of Luteinizing Hormone Receptor Activation : Hinge Region as a Key Player 

        Dhar, Neha (2018-06-05)
        GPCRs, influencing myriads of cellular functions, are the members of the largest family of the membrane proteins. However, their structures and the signaling mechanisms still remain enigmatic. In case of the Glycoprotein ...
      • Unravelling Crosstalk in Two-component Signalling Systems and Its Role in Mycobacterium Species 

        Singh, Devendra Pratap
        A typical two-component signaling system (TCSs) is composed of two transcriptionally coupled proteins (cognate pair) where one is a signal-sensing histidine kinase (HK) and the other, an output-generating response regulator ...
      • Unravelling The Mechanisms Of Myofibrillogenesis And Human Myopathies Using Drosophila Mutants 

        Salvi, Sheetal S (2013-07-18)
        Myofibrillogenesis is a complex process, which involves assembly of hundreds of structural proteins in a highly ordered manner to form the contractile structural unit of muscle, the sarcomere. Several myopathic conditions ...
      • Urolithin-A mitigates synaptic dysfunctions associated with epilepsy through VDAC1 inhibition: A novel therapeutic approach 

        Mishra, Shefali
        Urolithin-A mitigates synaptic dysfunctions associated with epilepsy through VDAC1 inhibition: A novel therapeutic approach Epilepsies are a group of neurological disorders with a prevalence of 70 million people worldwide ...
      • Xenopus Laevis TGF-ß: Cloning And Characterization Of The Signaling Receptors 

        Mohan, D Saravana (Indian Institute of Science, 2006-07-21)
        The amphibian species Xenopus laevis, along with mouse and chicken is a very important model system, used widely to dissect the molecular intricacies of various aspects of vertebrate development. Study with Xenopus has ...

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