Browsing Molecular Reproduction, Development and Genetics (MRDG) by Title
Now showing items 120-126 of 126
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Targeting Gonadotropins to the Dendritic Cells : A Novel Strategy for Animal Immunocontraceptive Vaccine
(2018-05-09)Contraception through a vaccine has been a very attractive proposition and several attempts were made in the past. To achieve contraception through immunological means, several points need to be considered. First, the ... -
Transcriptional and Posttranscriptional Regulation of the Tumor Suppressor CDC73 in Oral Squamous Cell Carcinoma : Implications for Cancer Therapeutics
(2018-04-16)CDC73, also known as HRPT2, is a tumour suppressor gene whose expression is lost or downregulated in parathyroid, renal, breast, uterine and gastric cancers. However, the reports regarding the role of CDC73 in oral squamous ... -
Understanding the role of hydrogen sulfide in regulating redox homeostasis and inflammation during cellular senescence
Aging involves the time-dependent deterioration of physiological functions, which can be attributed to various factors. Cellular senescence has been shown to be akin to aging, which involves alteration in redox homeostasis ... -
Unfolding the Mechanism of Notch1 Receptor Activation : Implications in Cancer Stem Cell Targeting
(2018-05-01)Notch receptors and ligands are single-pass transmembrane proteins which play important roles in cell-cell communication. Notch in ‘harmony’ with other signaling pathways regulate the entire diversity of metazoan life ... -
Unraveling the Mechanism of Luteinizing Hormone Receptor Activation : Hinge Region as a Key Player
(2018-06-05)GPCRs, influencing myriads of cellular functions, are the members of the largest family of the membrane proteins. However, their structures and the signaling mechanisms still remain enigmatic. In case of the Glycoprotein ... -
Unravelling The Mechanisms Of Myofibrillogenesis And Human Myopathies Using Drosophila Mutants
(2013-07-18)Myofibrillogenesis is a complex process, which involves assembly of hundreds of structural proteins in a highly ordered manner to form the contractile structural unit of muscle, the sarcomere. Several myopathic conditions ... -
Xenopus Laevis TGF-ß: Cloning And Characterization Of The Signaling Receptors
(Indian Institute of Science, 2006-07-21)The amphibian species Xenopus laevis, along with mouse and chicken is a very important model system, used widely to dissect the molecular intricacies of various aspects of vertebrate development. Study with Xenopus has ...