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    • Molecular Reproduction, Development and Genetics (MRDG)
    • Browsing Molecular Reproduction, Development and Genetics (MRDG) by Title
    •   etd@IISc
    • Division of Biological Sciences
    • Molecular Reproduction, Development and Genetics (MRDG)
    • Browsing Molecular Reproduction, Development and Genetics (MRDG) by Title
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    Browsing Molecular Reproduction, Development and Genetics (MRDG) by Title

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      • Gene Expression Profiling And Insights Into The Involvement Of The Insulin Signaling Pathway In Oral Cancer 

        Chakraborty, Sanjukta (2008-08-27)
        1. Despite extensive research on oral squamous cell carcinoma (OSCC), its five-year survival rate has not improved for the last two decades. Effective treatment of OSCC requires the identification of molecular targets to ...
      • Genetic Analysis of Wilson Disease in a South Indian Population and Molecular Characterization of 13 Novel ATP7B Mutations 

        Singh, Nivedita (2018-03-15)
        Wilson disease (WD) is an autosomal recessive disorder characterized by deposition of copper in the body, mainly in the liver and brain. WD patients present with hepatic, neurological, and psychiatric problems. The diagnosis ...
      • Genetic control of Embryonic and Adult muscle development in Drosophila melanogaster by Mlp60A 

        Wishard, Rohan
        Many genetic regulatory networks are required to define the overall characters in a living organism. Characters which are necessary for survival in the wild are often canalized, such that despite genetic and environmental ...
      • Genetics of Drosophila Indirect Flight Muscles : Unraveling the Roles of Genes Involved in Muscle Development and Function 

        Firdaus, Hena
        Myofibrillogenesis is a complex process involving assembly of many structural proteins in an orchestrated spatio-temporal manner to form a highly ordered contractile sarcomeric unit. Mutations in the proteins involved in ...
      • Glucose and Lipid Metabolism during Pregnancy and Lactation in Rats : Role of Undercarboxylated Osteocalcin 

        Pandey, Aparamita (2018-02-07)
        Energy homeostasis is an important physiological mechanism essential for balancingenergy flow through the living systems by managing overall metabolism in the body. Thus, energy homeostasis is under a tight control by means ...
      • Glycobiological Regulation of Breast Cancer Invasion 

        Pally, Dharma Tejeshwar Reddy
        Invasiveness of cancer is the predominant reason behind mortality associated with the disease. Although long under active investigation, fundamental aspects of the early steps of cancer invasion and metastasis are still ...
      • Guanylyl Cyclase C Regulation And Pathophysiology 

        Arshad, Najla (2015-02-26)
        The survival of the any living organism depends on its availability to communicate, and a breakdown of cellular signaling can have dire consequences such as uncontrolled cellular proliferations or even cell death. Environmental ...
      • Human Chorionic Gonadotropin : Insights Into Structure And Interactions With Its Receptor 

        Gadkari, Rupali A (2011-07-13)
      • Human Spermatogenesis : Differential Gene Expression And Regulation 

        Sanyal, Amartya (2010-08-24)
        Spermatogenesis is a complex process of male germ cell development in which the diploid spermatogonia undergo series of mitotic divisions and differentiation steps culminating into the preleptotene spermatocytes which then ...
      • Identification and Characterization of Molecular and Genetic Regulators of Cellular Senescence - Role of Free Radical Homeostasis 

        Bagheri, Meysam
        Aging is defined in an evolutionary biological context as a steady state decline in the specific fitness components of an organism due to internal physiological deterioration. The most profound and important contribution ...
      • Identification Of Domains Of The Follicle Stimulating Hormone Receptor Involved In Hormone Binding And Signal Transduction 

        Agrawal, Gaurav (2010-10-08)
        The glycoprotein hormones, Luteinizing Hormone (LH), human Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) are heterodimeric proteins with an identical α-subunit ...
      • Identification of Therapeutic Targets for Oral Squamous Cell Carcinoma 

        Avinash, Pradhan Shalmali (2018-04-03)
        Oral squamous cell carcinoma (OSCC) is the most common head and neck cancer, with a worldwide incidence of 275,000 new cases annually (Warnakulasuriya, 2009). Globally, the head and neck carcinoma represents a major cause ...
      • Immune-metabolic response of Caenorhabditis elegans to Enterococcus faecalis 

        Dasgupta, Madhumanti
        Immune response to pathogens is energetically expensive to the host. In this study, we show that Caenorhabditis elegans exposed for 8 hours to pathogenic Gram-positive bacteria, Enterococcus faecalis and Staphylococcus ...
      • Influence of Tgf-B on Mechanobiology of Human Breast Cancer Cells 

        Kulkarni, Ankur Hemant
        Breast cancers are characterized by extensive modifications to mechanical properties of the tissue via increased ECM production and vascularization. TGF-B is a multi-functional cytokine that is implicated in cancer invasion ...
      • Insight into luteolytic effects of repeated administration of LH in pregnant rats: Analysis of cAMP/PKA pathway during LH-induced luteolysis 

        Vashistha, Akshi
        The Corpus luteum (CL) is a dynamic endocrine structure that develops in the ovary from the remnants of the ovulated follicle and plays a critical role in the control of estrous/menstrual cycle as well as in establishment ...
      • Insights Into Cytostatic Mechanisms Regulated By Receptor Guanylyl Cyclase C 

        Basu, Nirmalya (2016-11-16)
        All cells are equipped to sense changes in their environment and make adaptive responses according to the stimuli. Signal recognition usually occurs at the cell membrane (with the exception of steroid signalling) where the ...
      • Insights into Differentiation of Mouse Pluripotent Stem Cells to Neural Lineage 

        Verma, Isha (2017-12-10)
        Pluripotent stem cells (PSCs: ESCs and iPSCs) provide an excellent model system for studying neural development and function. These cells also serve as a reliable source of cell replacement for the treatment of various ...
      • Insights into Differentiation of Pluripotent Stem Cells to Cardiac Progenitors and Cardiomyocytes 

        Sridharan, Divya
        The mammalian heart is the first organ formed during development. It forms the crux of the circulatory system of the body and pumps blood (and therefore, nutrients) to all parts of the body. The continuous functioning of ...
      • Insights Into Molecular Regulation Of Cardiomyocyte Differentiation Of Mouse Pluripotent Stem Cells 

        Abbey, Deepti (2015-08-03)
        Pluripotent stem cells (PSCs) are specialized cells, which have remarkable ability to maintain in an undifferentiated state and are capable of undergoing differentiation to three germ-layer lineage cell types, under ...
      • Insights into mRNA recruitment by eukaryotic initiation factor 4 during translation in Saccharomyces cerevisiae 

        Datey, Ayushi
        Ribosomes are responsible for synthesizing proteins in the cells by using mRNA as the template. However, the ribosomes cannot perform this function without the help of other protein factors. Different factors are required ...

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