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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title 
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    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title
    •   etd@IISc
    • Division of Biological Sciences
    • Department of Developmental Biology & Genetics (DBG, earlier called MRDG)
    • Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title
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    Browsing Department of Developmental Biology & Genetics (DBG, earlier called MRDG) by Title

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    Now showing items 84-103 of 151

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      • Mechanistic Insights into the Role of IGFBP-2 in Glioblastoma 

        Shilpa, S Patil (2018-08-13)
        Insulin like Growth Factor Binding Proteins (IGFBPs) 1 to 6 have important physiological functions of regulating half life and bioavailability of Insulin like Growth Factors (IGFs). Consequently, these have been known to ...
      • Mechanistic insights into the role of miR‐6741‐3p in oral squamous cell carcinoma pathogenesis 

        More, Dhanashree Anil
        Many functional studies and clinical analysis have linked miRNA dysregulation as a causative factor for tumor initiation and progression. Overexpression of oncogenic miRNAs and downregulation of tumor suppressor miRNAs are ...
      • Metallophosphoesterases In Mycobacteria Enigmatic Roles In Regulating Mycobacterial Physiology 

        Mattoo, Rohini (2014-04-29)
        Pathogenic bacteria such as M.tuberculosis have evolved several mechanisms to aid their intracellular survival and subvert host defenses. One of the contributing factors is thought to be the production and secretion of ...
      • Molecular Actions Of Arecoline, An Alkaloid Implicated In The Manifestation Of Oral Submucous Fibrosis (OSMF) 

        Singh, Thangam Gajan (2010-07-21)
        The pathogenesis of oral submucous fibrosis (OSMF) is due to a complex interplay between the production and degradation of extracellular matrix (ECM) protein components. In tissue fibrosis, there is a net accumulation of ...
      • Molecular Analysis Of Hamster Sperm Capacitation: Significance Of Protein Tyrosine Phosphorylation 

        Naveen, Daniel M (2007-12-17)
        Fertilization is a process that generates the first cell of a new organism. In mammals, fertilization occurs in the female reproductive tract. The male gametes (spermatozoa) are rendered fertilization-competent only after ...
      • Molecular Characterization Of The SLC22A18AS Gene From The Imprinted Human Chromosome Segment 11p15.5 

        Bajaj, Vineeta (2011-02-21)
        The imprinting status of the SLC22A18AS gene, located in the human chromosome segment 11p15.5, was studied using PCR-SSCP analysis and fetal tissues from a battery of 17 abortuses. This gene showed monoallelic expression ...
      • MOLECULAR GENETIC ANALYSIS OF THE TUBEROUS SCLEROSIS COMPLEX 

        Mahmood Ali, Abdullah (Indian Institute of Science, 2005-02-21)
        Tuberous sclerosis complex (TSC) is an autosomal dominant disorder that affects several organs in the human body including the brain, heart, kidneys, eyes, skin, spleen, liver and lungs [Roach, et al., 1999]. TSC is ...
      • Molecular insights into AMP-activated protein kinase (AMPK)-mediated regulation of anoikis resistance 

        Kumar, Saurav
        Our study identifies negative cross-talk between AMPK and two important cellular kinases, Akt and Erk. AMPK-mediated inhibition of these two kinases promotes survival of cancer cells in the matrix-deprived condition. ...
      • Molecular Phenotyping of Mutations in Guanylyi Cyclase C Associated with Congenital Diarrhea 

        Rasool, Insha (2018-02-28)
        Guanylyl cyclase C (GC-C) is a member of particulate guanylyl cyclases, discovered primarily as the target of a family of heat stable enterotoxins (ST), produced by enterotoxigenic Escherichia coli (ETEC). ST is acknowledged ...
      • Monoclonal Antibodies As Probes To Protein Structure And Function : Studies On Human Chorionic Gonadotropin 

        Venkatesh, N (2012-11-09)
      • Moonlighting Functions of the Rv0805 Phosphodiesterase from Mycobacterium Tuberculosis 

        Matange, Nishad (2018-04-18)
        All organisms must sense and respond to their environment in order to survive. The processes that allow a living cell to sense changes in its environment, and respond appropriately are collectively referred to as ‘signal ...
      • Neuroimmune Regulation in Caenorhabditis elegans: The Roles of the Amphid Sensory Neurons and Olfaction in Host Immune Responses 

        Venkatesh, Siddharth R
        The ability of hosts to rapidly sense invading pathogens and mount an appropriate response is paramount for host survival. Pathogens, pervasive in the natural world, present a perpetual threat to host organisms. Examining ...
      • Notch3 Receptor : Activation Mechanism and Association with Ovarian Cancer 

        Gera, Sakshi
        The Notch signaling influences a wide spectrum of cell fate decisions, both during development and in the adult organisms. This pleiotropic role of Notch signaling in humans is attributed partially to the presence of four ...
      • A Novel Family Of Soluble Diacylglycerol Acyltransferases 

        Saha, Saikat (2011-10-04)
      • Nucleic Acid-binding Adenylyl Cyclases in Mycobacteria : Studies on Evolutionary & Biochemical Aspects 

        Zaveri, Anisha (2018-02-08)
        Mycobacterium tuberculosis is one of the most successful human pathogens, estimated to have infected close to one-third of the global human population. In order to survive within its host, M. tuberculosis utilises multiple ...
      • Pathogen-derived volatiles modulate flight or fight response in Caenorhabditis elegans 

        Prakash, Deep
        In nature, the interaction between two organisms largely relies on their ability to sense and respond to each other, which involves many specific chemicals and signaling pathways. Animals have evolved mechanisms to detect ...
      • Peritoneal colonization of ovarian cancer 

        Sarkar, Purba
        The primary cause of mortality associated with cancer is metastasis, i.e., the spread of transformed cells from the site of oncogenesis to secondary loci within the body. Epithelial ovarian cancer (EOC) is a debilitating ...
      • The Phenomenon Of Blastocyst Hatching : Role Of COX-2 And NF-kB 

        Roy, Shubhendu Sen (2014-12-01)
        The zona-pellucida (zona, ZP) is an adhesion-refractory, acellular coat enclosing the rapidly growing, free-living mammalian preimplantation embryo which undergoes successive cleavage divisions to form the blastocyst, ...
      • Post-transcriptional Regulation Of Gene Expression : Role Of 3' Untranslated Region Of FSHBeta mRNA 

        Manjithaya, Ravi R. (2011-07-13)
      • Post-transcriptional regulation of the tumor suppressor gene TSC1 and its relevance in Oral Squamous Cell Carcinoma 

        Mallela, Karthik
        Oral cancer or oral squamous cell carcinoma (OSCC) is a subset of head and neck cancer (excluding non-melanoma skin cancer), with an estimated 354,864 new cases and 177,384 deaths reported annually. India accounts for 34% ...

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