Browsing Division of Biological Sciences by Title
Now showing items 860-879 of 1020
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Studies on NMPylase and Valine Catabolism Enzymes from Mycobacterium
Post-translational modifications constitute an important arm of the regulatory mechanism in mammalian cells. Therefore, bacterial pathogens, which thrive by mimicking the host cell signaling, are proving to be difficult ... -
Studies on Novel Functional Responses of Mouse Peritoneal Macrophages to Interferon-gamma : Roles of Nitric Oxide Synthase 2
(2018-04-18)Interferons are known cytokines that display antiviral, anti-proliferative and immuno-modulatory functions in the host. Interferon-gamma (Ifnγ) is the only type II family interferon that binds to the heterodimeric receptor ... -
Studies on Nudix hydrolase proteins and crosstalk between DNA repair pathways
Mycobacterium tuberculosis, the causative agent of tuberculosis, has become a global health concern. This calls for a dire need to understand various aspects of mycobacterial physiology in order to design better strategies ... -
Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication
(2016-04-28)Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae ... -
Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners
(2010-03-26)PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ... -
Studies on Regulation of Rat Corpus Luteum Function by Prolactin And Luteinizing Hormone
(2018-07-25)The corpus luteum (CL) is a transient endocrine structure formed from the remnants of an ovulated follicle with the primary purpose of producing progesterone (P4), a hormone vital for the establishment and maintenance of ... -
Studies on Rotavirus Nonstructural Protein 5 (NSP5)
Rotavirus is the most important agent of viral gastroenteritis in humans and animals and is responsible for about 600,000 deaths per annum. Most of these deaths occur in the developing countries and India is estimated to ... -
Studies On Saccharomyces Cerevisiae RNA Polymerase II Subunit Rpb7 And Its Eukaryotic Orthologs
(2010-06-03)Saccharomyces cerevisiae is an excellent experimental model organism to study various biological processes owing to its versatile genetics, biochemistry, and standard laboratory conditions. S. cerevisiae shows distinct ... -
Studies On Sesbania Mosaic Virus Asssembly And Structure And Function Of A Survival Protein (SurE) From Salmonella Typhimurium
(2011-03-29)X-ray crystallography is a powerful method for determining the three-dimensional structures of biological macromolecules at atomic resolution. Crystallography can reliably provide the answer to many structure related ... -
Studies on the Evolution of Aromatic Beta-Glucoside Catabolic Systems under Different Stress Conditions in Escherichia coli
(2017-11-22)The genetic systems involved in the utilisation of aromatic β-glucosides in E. coli consist of the bgl, asc, and chb operons and the locus bglA encoding phospho-β-glucosidase A. The bgl and asc operons are known as cryptic ... -
Studies On The Expression Of The bgl Operon Of Escherichia Coli In Stationary Phase
(2010-03-19)The bgl operon of Escherichia coli, involved in the uptake and utilization of aromatic β-glucosides salicin and arbutin, is maintained in a silent state in the wild type organism by the presence of structural elements in ... -
Studies On The Functional Roles Of Peptidase N, A M1 Family Member, During Stress And Infection
(2014-08-11)The cytosolic protein degradation pathway, performed by ATP-dependent proteases and ATP-independent peptidases, plays important roles in several cellular activities, e.g. cell division, cell cycle progression, intracellular ... -
Studies On The Mechanism Of Uracil Excision Repair In Escherichia Coli And Structure-Function Relationship Of Single Stranded DNA Binding Proteins From Escherichia Coli And Mycobacterium Tuberculosis
(2014-12-11)To maintain the genomic integrity, cell has evolved various DNA repair pathways. Base Excision Repair pathway (BER) is one such DNA repair pathway which is dedicated to protect DNA from small lesions such as oxidation, ... -
Studies On The Mechanisms Involved In Thymic Atrophy During Salmonella Enterica Serovar Typhimurium Infection
(2015-09-04)T lymphocytes are an essential component of the adaptive immune response and are highly versatile in function. Each T cell has a unique T cell receptor that can recognize an antigenic peptide in the context of the major ... -
Studies On The Molecular Mechanism Of Cytokinin Action: Involvement Of Ca2+, Protein Kinase And Concurrent Protein Synthesis In Signaling Of Cytokinin-Induced Expression Of Pathogenesis-Related Enzymes In Cucumber
(Indian Institute of Science, 2005-12-08)Phytohormones act as signals to regulate plant growth and development by modulation of gene expression in response to internal developmental cues or external environmental stimuli, such as light and pathogen infection. ... -
Studies On The Phenomenon Of Blastocyst Hatching: Role Of Cysteine Proteases
(2007-11-16)The mammalian embryo is encased in a glycoproteinaceous covering, the zona pellucida (ZP/zona) during preimplantation development. Prior to implantation into the recipient maternal endometrium, the blastocyst has to hatch ... -
Studies on the post-transcriptional regulation of genes of glutamate utilization pathway in Pichia pastoris and a role for Retrograde regulation protein 1
The methylotrophic yeast, Pichia pastoris can utilize compounds such as glucose, glycerol, methanol, acetate, amino acids, or oleic acid as the sole source of carbon. However, the regulation of synthesis of key enzymes of ... -
Studies on the promoter specificity determinants and modulators of the prokaryotic transcription machinery
Bacteria adapt to a wide range of environmental conditions by synchronizing transcription with changes in the extracellular environment. This is achieved by the synchronized action of two-component systems, Extra Cytoplasmic ... -
Studies on the regulatory roles for Retinoic Acid (RA) during host-microbial interaction : implications for S. aureus and C. albicans infections
Chronic inflammatory disorder is one of the leading causes of death worldwide. Association between pathogenic infection and inflammation governs tissue homeostasis, which relies on extensive crosstalk among signaling ...