Mutualism involves exchange of services and rewards between the partners, resulting in a net benefit to all those involved. In many mutualisms, hosts are larger partners that interact with several individuals of smaller ...

Mycobacterium tuberculosis (Mtb) has evolved as an important clinical pathogen due to its ability to gain multidrug resistance, to enter into latency to persist there and to get reactivated from the latent infection in ...

Rinderpest virus (RPV) belongs to the order Mononegavirale which comprises non segmented negative sense RNA viruses including human pathogens such as Measles, Ebola and Marburg virus. RPV is the causative agent of Rinderpest ...

Cells constantly encounter genotoxic stress arising from extrinsic environmental factors or intrinsic metabolic byproducts. In response, cells activate a robust DNA damage response (DDR) network to preserve genomic stability. ...

Biological systems exhibit considerable heterogeneity in their constitutive components and encounter stochasticity across all scales of analysis. Therefore, central questions that span all biological systems are: (a) How ...

Chromatin is a dynamic structure which reorganizes to support numerous chromosomal processes. Various histone and non-histone proteins are involved in chromatin organization. One such group of non-histone proteins, known ...

The connection between 3D-genome organization and genome regulation is one of the fundamental questions in modern biology. In a nucleus, the genome is organized through different layers of 3D-organization such as ...

Cancer progression is a multi-step process requiring cells to acquire specific properties that aid the neoplastic growth. One such property is the ability to survive in the absence of matrix-attachment, a critical necessity ...

Rifampicin is a non-competitive inhibitor of bacterial RNA polymerase (RNAP). The knowledge about the mechanism of action of this drug has emanated from the genetic and the biochemical studies carried out on Escherichia ...