Browsing Division of Biological Sciences by Title
Now showing items 870-889 of 1038
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Studies On Initiator tRNA Selection On The Ribosomes In Escherichia Coli
(2009-05-06)The studies reported in this thesis address the aspects of initiator tRNA selection in Escherichia Coli. A summary of the relevant literature discussing the process of ptotein biosynthesis in general and initiator tRNA ... -
Studies on Interactions between ARE Binding Proteins and Splicing Factors and their Role in Altered Splicing of PDGF-B ORF
(2018-03-03)Pre-mRNA splicing is an important level in posttranscriptional gene regulation that is essential for accurate protein synthesis and generating protein diversity. The abundance of cryptic splice sites and long intronic DNA ... -
Studies On Intracrine Regulators Of Ovarian Function : Examination Of Progesterone Action On Structure And Function Of Corpus Luteum In The Monkey
(2011-08-09)The control of reproductive cycles in higher primates is largely dependent on negative and positive feedback mechanisms by both steroidal and non-steroidal substances of the ovaries which regulate the function of ... -
Studies On Molecular Analysis Of Capacitation Associated Protein Tyrosine Phosphorylation In Hamster Spermatozoa
(2014-04-07)In mammals, freshly ejaculated spermatozoa do not possess the ability to fertilize a mature oocyte. They acquire fertilization competence upon residing for a period of time in the female reproductive tract. The physiological ... -
Studies on Molecular Targets and Pathways Regulated by Rice RFL for Flowering Transition and Panicle Development
(2017-11-28)LFY of Arabidopsis is a member of a unique plant specific transcription factor family. It is involved in giving meristem a determinate floral fate by the activation of floral organ identity genes and preventing inflorescence ... -
Studies on NMPylase and Valine Catabolism Enzymes from Mycobacterium
Post-translational modifications constitute an important arm of the regulatory mechanism in mammalian cells. Therefore, bacterial pathogens, which thrive by mimicking the host cell signaling, are proving to be difficult ... -
Studies on Novel Functional Responses of Mouse Peritoneal Macrophages to Interferon-gamma : Roles of Nitric Oxide Synthase 2
(2018-04-18)Interferons are known cytokines that display antiviral, anti-proliferative and immuno-modulatory functions in the host. Interferon-gamma (Ifnγ) is the only type II family interferon that binds to the heterodimeric receptor ... -
Studies on Nudix hydrolase proteins and crosstalk between DNA repair pathways
Mycobacterium tuberculosis, the causative agent of tuberculosis, has become a global health concern. This calls for a dire need to understand various aspects of mycobacterial physiology in order to design better strategies ... -
Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication
(2016-04-28)Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae ... -
Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners
(2010-03-26)PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ... -
Studies on Regulation of Rat Corpus Luteum Function by Prolactin And Luteinizing Hormone
(2018-07-25)The corpus luteum (CL) is a transient endocrine structure formed from the remnants of an ovulated follicle with the primary purpose of producing progesterone (P4), a hormone vital for the establishment and maintenance of ... -
Studies on Rotavirus Nonstructural Protein 5 (NSP5)
Rotavirus is the most important agent of viral gastroenteritis in humans and animals and is responsible for about 600,000 deaths per annum. Most of these deaths occur in the developing countries and India is estimated to ... -
Studies On Saccharomyces Cerevisiae RNA Polymerase II Subunit Rpb7 And Its Eukaryotic Orthologs
(2010-06-03)Saccharomyces cerevisiae is an excellent experimental model organism to study various biological processes owing to its versatile genetics, biochemistry, and standard laboratory conditions. S. cerevisiae shows distinct ... -
Studies On Sesbania Mosaic Virus Asssembly And Structure And Function Of A Survival Protein (SurE) From Salmonella Typhimurium
(2011-03-29)X-ray crystallography is a powerful method for determining the three-dimensional structures of biological macromolecules at atomic resolution. Crystallography can reliably provide the answer to many structure related ... -
Studies on the Evolution of Aromatic Beta-Glucoside Catabolic Systems under Different Stress Conditions in Escherichia coli
(2017-11-22)The genetic systems involved in the utilisation of aromatic β-glucosides in E. coli consist of the bgl, asc, and chb operons and the locus bglA encoding phospho-β-glucosidase A. The bgl and asc operons are known as cryptic ... -
Studies On The Expression Of The bgl Operon Of Escherichia Coli In Stationary Phase
(2010-03-19)The bgl operon of Escherichia coli, involved in the uptake and utilization of aromatic β-glucosides salicin and arbutin, is maintained in a silent state in the wild type organism by the presence of structural elements in ... -
Studies On The Functional Roles Of Peptidase N, A M1 Family Member, During Stress And Infection
(2014-08-11)The cytosolic protein degradation pathway, performed by ATP-dependent proteases and ATP-independent peptidases, plays important roles in several cellular activities, e.g. cell division, cell cycle progression, intracellular ... -
Studies On The Mechanism Of Uracil Excision Repair In Escherichia Coli And Structure-Function Relationship Of Single Stranded DNA Binding Proteins From Escherichia Coli And Mycobacterium Tuberculosis
(2014-12-11)To maintain the genomic integrity, cell has evolved various DNA repair pathways. Base Excision Repair pathway (BER) is one such DNA repair pathway which is dedicated to protect DNA from small lesions such as oxidation, ...