Browsing Division of Biological Sciences by Title
Now showing items 710-729 of 1026
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Roles of Protein Acetylation in the Human Pathogen Helicobacter pylori
Helicobacter pylori is a gram-negative epsilon proteobacterium infecting half of the world population. H. pylori is a naturally competent bacterium with a huge repertoire of Restriction-Modification (RM) systems. The ... -
Roles of the ribosomal protein uS12 and the initiation factor 3 in the maintenance of fidelity of translation in Escherichia coli
The flow of genetic information within biological systems according to the central dogma of molecular biology entails protein synthesis as the last step towards deciphering the message encrypted in the genetic code in ... -
Rotavirus Viroplasm Structure (VS) : The First Insights into the Architectural Assembly of the Viral and Host Factors in the VS"
Rotavirus is a major cause of acute gastroenteritis in infants and young children and responsible for approximately 453,000 infantile deaths per year. Rotaviruses are non-enveloped RNA viruses belonging to the Reoviridae ... -
Rv0805, a novel regulator of central carbon metabolism and cell envelope properties in mycobacteria
Metabolic flexibility is one of the key factors that underpin mycobacterial physiology and pathogenesis. During infection, mycobacteria shift towards utilising host-derived fatty acids, lipids, cholesterol and cholesterol-esters. ... -
Salmonella Pathogenesis in Dendritic Cells : Stealthy Approach Against Adaptive Immune Response
Synopsis of work done by Mayuri Gogoi (SR No. 10-09-00-10-31-11-1-08534) for the award of Ph.D. degree in the Faculty of Science, Indian Institute of Science, Bangalore, India. Thesis title: Salmonella pathogenesis in ... -
Scanning mutagenesis studies of HIV-1 Env immunogenicity and structure
Human Immunodeficiency Virus type 1 (HIV-1) is the etiological agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a global pandemic with 36.7 million people living with HIV-1 all over the world and approximately ... -
Secondary Structures in Proteins : Identification and Analyses
(2018-07-12)Proteins are large biomolecules consisting of one or more long chains of amino acid residues. They perform a vast array of functions within living organisms. In this thesis, we present analyses of different secondary ... -
Seed Dispersal In The Tropical Dry Forests Of Mudumalai, Southern India
(2011-06-30)Plants depend on a wide variety of vectors, both biotic and abiotic, to move their seeds to locations away from parent plants. The stages between seed production and seedling establishment in the plant life cycle are under ... -
Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution
(2010-09-30)Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ... -
Sensory Ecology Of Acoustic Communication In The Tropical Bushcricket Genus Mecopoda : Mechanisms And Evolution Of Synchrony
(2009-07-10)In this thesis, I characterise five species of the bushcricket genus Mecopoda with respect to their acoustic signals and morphology and investigate the phenomenon of acoustic synchrony in one of these five species: Mecopoda ... -
Sequence Analysis And Design Of Immunogens From The Stem Domain Of Influenza Hemagglutinin
(2013-07-10)Influenza is an important respiratory pathogen that infects several million people each year. Currently available flu vaccines have to be updated regularly in order to be effective as the virus changes its composition by ... -
Sequence And Structural Determinants of Helices in Membrane Proteins
(2017-09-23)Membrane proteins roughly constitute 30% of open reading frames in a genome and form 70% of current drug targets. They are classified as integral, peripheral membrane proteins and polypeptide toxins. α-helices and β -strands ... -
Sexual Selection On Elephant Tusks
(2017-06-12)Darwin was troubled by elaborate male traits observed in many species that are seemingly maladaptive for survival, the peacock’s tail being the most iconic of all. He wrote "The sight of a feather in a peacock’s tail, ... -
Single-channel studies on human TREK-1 (hTREK-1) channels to intracellular ischemia related factors
TREK-1, a member of the two-pore domain family of potassium channels, majorly contributes to the maintenance of resting membrane potential of a cell and has been reported to respond to ischemic levels of intracellular ... -
Small Heat Shock Proteins from Bacteria and a Bacteriophage
Proteins can unfold during heat and other types of stress and tend to aggregate with subsequent loss of function. This event is prevented by small Heat Shock Proteins (sHSPs) acting as molecular chaperones. sHSPs do not ... -
Small Heat Shock Proteins from Oryza Sativa and Salmonella Enterica
(2018-05-09)Small heat shock proteins (sHSPs) are a ubiquitous family of molecular chaperones that play a vital role in maintaining protein homeostasis in cells. They are the first line of defence against the detrimental effects of ... -
Social Organisation And Cooperation In Genetically Mixed Colonies Of The Primitively Eusocial Wasp, Ropalidia Marginata
(Indian Institute of Science, 2005-08-05)Altruism in its extreme form is seen in social insects where most individuals give up their own reproduction and work to rear the offspring of their queen. The origin and evolution of such sterile worker castes remains a ... -
Soil microorganisms and biogeochemical cycles in a grazing ecosystem: interactions between producers, consumers, and decomposers
Microorganisms are the unseen majority that determines ecosystem processes, they perform biogeochemical functions that translate into essential services, and regulate global climate. In grazing ecosystems, which represent ... -
Solution NMR studies of a potent subtilisin inhibitor from Budgett’s frog and the catalytic subunit of AHAS
This thesis involves a detailed structural study of two molecular systems, a small disulfide-rich peptide LL-TIL and a large catalytic subunit of AHAS. Subtilisin inhibitors play an important role in fighting against ... -
Solution NMR Studies Of E.Coli Acetohydroxy Acid Synthase (AHAS) I
(2010-04-13)Branched chain amino acids are classified as essential amino acids since their biosynthetic routes or pathways are restricted only to micro-organisms, fungi and plants. Given their unique distribution, the enzymes of the ...