Browsing Division of Biological Sciences by Title
Now showing items 614-633 of 1026
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Protein-DNA Graphs And Interaction Energy Based Protein Structure Networks
(2013-01-29)Proteins orchestrate a number of cellular processes either alone or in concert with other biomolecules like nucleic acids, carbohydrates, and lipids. They exhibit an intrinsic ability to fold de novo to their functional ... -
Protein-small molecule interactions: Structural insights and applications in computational drug discovery
Deviation from normal healthy conditions, termed as disease, can often be triggered due to the malfunctioning of proteins. Modulating the functions of proteins by administering therapeutic agents (drugs) may alleviate the ... -
Proteomic Approaches to Study Glioma Development, Progression and Therapy
(2018-04-02)Astrocytoma, the tumor of astrocytic origin, accounts for about 60 % of the primary brain tumors. As per World Health Organization grading system, astrocytoma is classified as circumscribed astrocytoma (Grade I; pilocytic ... -
Proteomics-based Identification of Serum Biomarkers : Role of Secreted MCSF and CRP in Glioma Pathogenesis
Gliomas are the neoplasia of glial cells present in the brain and comprises of more than 70% of all the neoplasms of the central nervous system. They consist of a family of primary brain tumors that are categorized based ... -
Qualitative similarities and differences between monkey and human visual perception
Animal models play a crucial role in helping neuroscientists unravel the computations supporting behaviour at the resolution of a single neuron in the brain. In vision science, the macaque monkey is the pre-eminent model ... -
Queen Succession in the Primitively Eusocial Wasp Ropalidia Marginata
(2018-01-04)Social insects are the most dominant terrestrial fauna for the last 50 million years. This tremendous ecological success is accompanied by the fact that sociality has evolved multiple times independently and achieved highest ... -
Queens And Their Succerssors : The Story Of Power In The Primitively Eusocial Wasp Ropalidia Marginata
(2009-04-30)Ropalidia marginata is characterized as a primitively eusocial wasp due to the absence of morphological differentiation between the queen and worker castes. Unlike other primitively eusocial wasps, however, the queen in ... -
Racemases in Salmonella : Insights into the Dexterity of the Pathogen
(2018-02-27)Chapter -I Introduction Salmonella is a pathogen well-known for its ability to infect a wide variety of hosts and causes disease ranging from mild gastroenteritis to typhoid fever. During infection, it is exposed to a ... -
Rational Elicitation of Cold Sensitive Phenotypes
Conditional gene expression and conditional mutants provide a means to modulate the expression of specific genes and to control the activity of their protein products in vivo, so as to be able to study their effects on the ... -
Receptor Guanylyl Cyclase C Cross-talk With Tyrosine Kinases And The Adaptor Protein, Crk
(2009-03-06)Signal transduction is a crucial event that enables cells to sense and respond to cues from their immediate environment. Guanylyl cyclase C (GC-C) is a member of the family of receptor guanylyl cyclases. GC-C is a single ... -
Regulation and Characterization of Transcription Factor Activator Protein-2 Alpha (AP-2α)
(2018-02-11)Introduction AP2α is a 52 kDa retinoic acid inducible and developmentally regulated activator of transcription, which binds to the DNA in a sequence-specific manner. Transcription factor AP-2α was isolated from HeLa cells ... -
Regulation of auxin response by UBIQUITIN-SPECIFIC PROTEASE14/ TARANI in Arabidopsis thaliana
The genetic pathway regulating auxin response in Arabidopsis is well established and provides us a framework to assess whether TNI belongs to this pathway. The total number of lateral roots is taken as a read-out of auxin ... -
Regulation of carbon metabolism in Pichia pastoris by Mxr1p and identification of novel regulators
Pichia pastoris (a.k.a. Komagataella phaffii), a widely used yeast for recombinant protein production, is cultured under a variety of conditions ranging from shake flasks to large bioreactors employing minimal, chemically ... -
Regulation of Chitin Oligosaccharides Utilization in Escherichia Coli
(2018-04-11)The genome of Escherichia coli harbors several catabolic operons involved in the utilization of a wide variety of natural compounds as carbon sources. The chitobiose (chu) operons of E.coli Is involved in the utilization ... -
Regulation of Expression of p53 and its Isoform Δ40p53 : Consequences on Cellular Gene Expression
The TP53 tumour suppressor gene encodes for p53 protein which is the frequently altered gene in most of the cancers. p53 protein is activated in response to different stresses and plays major role in maintaining genome ...