Browsing Division of Biological Sciences by Title
Now showing items 503-522 of 1477
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Immunochemical Studies on the family of Biotin Binding Proteins
(Indian Institute of Science, 2005-04-29)Investigations detailed in this thesis constitue a part of continuing programme of research work undertaken in this laboratory on vitamin binding proteins. Avidin from the chicken egg white, streptavidin &om the bacterium ... -
Immunogen design to enhance Influenza and SARS-CoV-2 vaccine efficacy
Influenza and SARS-CoV-2 are pleomorphic viruses that cause respiratory diseases in humans and present significant public health threats. Vaccination has been essential in controlling the spread of these infections and ... -
Immunological consequences of host signaling-regulated epigenetic modification(s) during mycobacterial pathogenesis
Introduction: Mycobacterium tuberculosis (Mtb), the principal etiological agent of pulmonary tuberculosis (TB), continues to co-evolve with the human population making itself one of the most potent infectious killer in the ... -
Immunological insights into Epidermal Growth Factor Receptor Signaling: Implications for host-pathogen interactions
Infectious diseases account for a large proportion of morbidity and mortality worldwide. The major global efforts lie in effectively enhancing the health span of infected individuals and more importantly, curbing infection ... -
Immunomodulatory Activity of Glycodelin : Implications in Allograft Rejection
(2018-06-15)Glycodelin, a homodimeric glycoprotein belonging to the lipocalin superfamily, is synthesised predominantly by the cells of the reproductive system of certain primates including humans. Of the four different known glycoforms ... -
Immunomodulatory effects of 7-hydroxy frullanolide, a plant-based sesquiterpene lactone, in inhibiting immune cell responses and roles of disease and vaccination outcomes on Covid-19 mortality
Immunomodulation is a process by which the immune response of the host is either enhanced or suppressed due to various factors which either protects or makes the host more susceptible to particular diseases. Immunomodulators ... -
Immunoneutralization Of Cytotoxic Abrin : Insights Into Mechanisms And Therapy
(2015-12-02)Type II Ribosome Inactivating Proteins (RIPs), commonly known as A/B toxins are heterodimers comprising of a catalytically active A chain, an RNA N-glycosidase which inhibits protein synthesis and a lectin-like B chain ... -
Impact of low-dose radiation in inducing mitochondria dependent inflammaging - A new model for cellular senescence
Recent advances in the field of aging have identified cellular senescence as one of the major hallmarks of aging and the accumulation of senescent cells in a biological system is associated with inflammation and many age ... -
Implications of Soluble Diacylglycerol Acyltransferases in Triacylglycerol Biosynthesis in Yeast and Plants
(2018-04-12)Lipids are stored in a cell for providing energy. The main advantages of storing lipids over carbohydrates like glycogen is that, lipids yield more energy after oxidation because they represent the highly reduced form of ... -
Importance of formylation in eubacterial translation initiation
Initiation of protein synthesis in all organisms occurs with the amino acid methionine. In the case of eubacteria and eukaryotic organelles, methionine is further modified to formylmethionine by the enzyme methionyl?tRNA ... -
Improvement in the nutritive value of tomatoes : vitamin A potent tomatoes and some aspects of carotenoid and vitamin A
Chapter 1 Different tomato varieties that are commonly cultivated in our country differ in their yield, size and shape of the fruit, disease resistance etc. However, all of them contain very little amount of carotene, ... -
Improving Glioblastoma Management: A Study of Biomarkers, Tumor Microenvironment and Chemoresistance
Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant chemotherapy with temozolomide. ... -
In Silico Perspectives on RNA Structures Modulating Viral Gene Expression and Mechanics of tRNA Transport
(2018-07-19)The repertoire of cellular functions mediated by Ribonucleic acid (RNA) molecules have expanded considerably during the last two decades. The role played by RNA in controlling and regulating gene expression in ... -
In vitro studies on the biosynthesis of allergens of parhenium hysterophorus and cytotoxicity of parthenin
Parthenium hysterophorus, like several other members of the Compositae, causes allergic contact dermatitis and hay-fever in humans. Besides this, it is also ecologically dominant and is toxic to livestock. The allergic ... -
In vivo mechanistic insights into the trans-splicing based expression of Hsp90 in Giardia lamblia
Giardia lamblia, a simple yet intriguing protozoan parasite, challenges conventional paradigms in gene expression through its unique mechanism of trans-splicing for Heat Shock Protein 90 (Hsp90). As a primitive organism, ... -
Inactivation of HMGCoA reductase by disulfides hydrogenperoxide silatrame and ubiquinone
Abstract not available -
Indoeacetaldoxime hydro-lyase of gibberella fujikoroi
In the following pages, the work described in the preceding chapters has been summarized. The conversion of IAOX to IAN was shown to be an enzymatic process. Culture conditions for the growth of Gibberella fujikuroi ... -
Infection of Human Cell Lines by Japanese Encephalitis Virus : Increased Expression and Release of HLA-E, a Non-classical HLA Molecule
(2018-04-24)Japanese encephalitis virus (JEV) causes viral encephalitis in new born and young adults that is prevalent in different parts of India and other parts of South East Asia with an estimated 6000 deaths per year. JEV is a ...