Browsing Division of Biological Sciences by Title
Now showing items 462-481 of 1425
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Human chorionic gonadotropin : Recombinant DNA expression and structure-function relationship studies
Human Chorionic Gonadotropin (hCG) is a member of the family of glycoprotein hormones, which also includes the pituitary-derived Thyroid Stimulating Hormone (TSH), Follicle Stimulating Hormone (FSH), and Luteinizing Hormone ... -
Human Immune Response To Japanese Encephalitis Virus Guides Development Of Vaccines With Long Lasting Immunity
(2013-05-21)Chapter 1: Role of JEV NS1 in protective immunity and in immunopathology. Previous studies from our laboratory revealed T cell immunodominance of non structural proteins NS3 and NS1 during natural JEV infections in humans ... -
Human Spermatogenesis : Differential Gene Expression And Regulation
(2010-08-24)Spermatogenesis is a complex process of male germ cell development in which the diploid spermatogonia undergo series of mitotic divisions and differentiation steps culminating into the preleptotene spermatocytes which then ... -
Hydration, mobility and action of proteins : an x-ray study involving hen-egg-white lysozyme and human hemoglobin
Hydration and mobility of proteins have received considerable attention. It is also recognized that the two are related. A long-range protein crystallographic program in this laboratory is concerned with protein hydration ... -
Identification and Biochemical Characterization of Novel Inhibitors of Nonhomologous End Joining: Implications in DNA Double-Strand Break Repair and Cancer Therapy
To summarize, in the present study, we have synthesized and characterized three novel NHEJ inhibitors targeting DNA Ligase IV, with several fold better efficacy compared to SCR7 and thus potential to be developed as cancer ... -
Identification and Characterisation of a miRNA releasing activity from Caenorhabditis elegans
MicroRNAs (miRNA) are endogenous, small non coding RNAs, which play a prominent role in eukaryotic gene regulation. Perturbations leading to an altered abundance of miRNAs can lead to pathological conditions like neurological ... -
Identification And Characterisation Of Two Silencing Barrier Sequences In Saccharomyces Cerevisiae
(2010-07-21)In eukaryotic cells, genomic DNA exists as chromatin in association with histone octamers called nucleosomes, and various other chromatin proteins. Chromatin structure varies along the chromosome and this influences the ... -
Identification And Characterization Of A Virus Inducible Non Coding RNA (VINC)
(2010-12-29)Non-protein coding eukaryotic genome sequences often referred to as junk DNA are estimated to encode several non-coding RNAs (ncRNAs) which may account for nearly 98% of all genomic output in humans. The output of such a ... -
Identification and Characterization of Interacting Proteins of TARANI/ Ubiquitin Specific Protease-14 in Arabidopsis thaliana
Regulation of organ shape and size is an important area of research in developmental biology in both plants and animals. The shape of a leaf is determined primarily by endogenous factors such as gene function. Only a ... -
Identification and Characterization of Molecular and Genetic Regulators of Cellular Senescence - Role of Free Radical Homeostasis
Aging is defined in an evolutionary biological context as a steady state decline in the specific fitness components of an organism due to internal physiological deterioration. The most profound and important contribution ... -
Identification of actin as an estradiol 17-Beta-Stimulated protien in the human placenta
The human placenta develops by an association of maternal and fetal tissues and performs many important functions during pregnancy. It facilitates the transport of nutrients from the mother to the fetus, the exchange of ... -
Identification Of Chloroquine Resistant Haplotypes Of Plasmodium Falciparum In India And Development Of New Antimalarial Combinations
(2008-10-03)Malaria afflicts 300-500 million people in the world and the mortality ranges from 1-2 million, children in Africa being the most susceptible. With a vaccine not being available against malaria and the front line drugs ... -
Identification Of Domains Of The Follicle Stimulating Hormone Receptor Involved In Hormone Binding And Signal Transduction
(2010-10-08)The glycoprotein hormones, Luteinizing Hormone (LH), human Chorionic Gonadotropin (hCG), Follicle Stimulating Hormone (FSH) and Thyroid Stimulating Hormone (TSH) are heterodimeric proteins with an identical α-subunit ... -
Identification Of GAL102 Encoded UDP-Glucose 4, 6 Dehydratase Activity, As A Novel Virulence Factor In Candida Albicans
(2014-08-11)Among fungal pathogens responsible for opportunistic infections, species of the genus Candida have a major role (Mitchell, 1998). Various Candida species cause superficial infections which can be cured by the currently ... -
Identification Of Key DNA Elements Involved In promoter Recognition By Mxr1p , A key Regulator Of Methanol Utilisation Pathway In Pichia Pastoris
(2010-04-09)The methylotrophic yeast Pichia pastoris is widely used for recombinant protein production due to its ability to grow to high cell densities as well as possession of an inducible methanol utilization pathway (MUT). The ... -
Identification of the Minimal Domain of RNA Trihosphastase Activity in the L Protien of Rinderpest Virus and Charecterization of its Enzymatic Activities
(2018-04-03)Morbilliviruses belong to the family Paramyxoviridae of the Mononegavirale order of viruses. The Mononegavirale order contains viruses which contain negatively-polar, non-segmented and single stranded RNA genomes. This ...