Browsing Division of Biological Sciences by Title
Now showing items 302-321 of 1513
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Effect Of Glycodelin A On Cells Of The Immune System Insights Into GdA-Induced Signaling In Monocytes, B And NK Cells
(2010-04-06)Glycodelin is a 162 amino acid dimeric, glycosylated, secretory protein of the lipocalin superfamily. Its classification as a lipocalin(carriers of small hydrophobic molecules) is based mainly on the presence of lipocalin ... -
Effect of sequence on DNA structure : Insights from molecular dyanmics studies
DNA is a flexible molecule, known to adopt a wide variety of structures ranging from right-handed A, B, C to left-handed Z DNA and higher-order structures like quadruplexes, depending on the sequence and environment. This ... -
Effect of Stimulus Normalization and Visual Attention at multiple scales of Neural Integration
The effect of visual attention on neural signals has been extensively studied using various techniques such as macaque neurophysiology and human electro/magneto encephalogram (EEG/MEG). Depending on the technique, different ... -
Effect of the stress hormone corticosterone on synaptic transmission and astrocytic release
Glucocorticoids have been shown to influence neuronal function and metabolism in multiple ways. They regulate a wide array of actions-from maintaining cellular homeostasis to mediating stress responses-via myriad downstream ... -
Effect of Ultrasound on Neuronal Network Communication
(2018-05-22)Low intensity and low frequency ultrasound has been shown to modulate ion channel currents, membrane capacitive currents, and as a result, neuronal activity. Ultrasound has been used as a non-invasive way to modulate ... -
Effects of Cyclic Permutation, Glycan Removal and Aspartate Mutagenesis on Conformation of HIV-1 Envelope
It has been decades since Human Immunodeficiency Virus-1 (HIV-1) was discovered. The virus has created havoc worldwide. According to the UNAIDS 2014 Gap report, 35million people worldwide are infected with HIV-1 and yet ... -
Effects of Steroid Hormones on Insulin Sensitivity and Lipogenesis: An Insight into the Involvement of the Wnt Signaling Pathway
The shift in maternal energy metabolism characteristic of pregnancy is thought to be driven by various hormonal changes, especially of ovarian and placental steroids. In this context, the effect of estradiol (E2), progesterone ... -
Electrophysiological studies investigating drug effects on hHCN1 channels and Unravelling pore dynamics in Pannexin channels
Hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channel stands out for its unique characteristics, including sensitivity to transmembrane voltage and cyclic nucleotides, as well as its non-selective passage ... -
Elucidating Deregulated Novel Pathways in Glioma through Genetic and Epigenetic Approaches
Malignancy of glial cells is termed as glioma. Gliomas comprise of thirty percent of all tumors of the central nervous system (CNS) and eighty percent of malignant brain tumors (Goodenberger and Jenkins, 2012). Astrocytoma, ... -
Elucidating mechanisms regulating GC-C signalling in colorectal cancer
Colorectal cancer is the third most frequently diagnosed cancer and the second major cause of cancer death worldwide. Classical therapies for treating colorectal cancer are mostly nonspecific and, therefore, are associated ... -
Elucidating the diverse functions of RGG-motif containing proteins
One year embargo upto 20/2/2026 RGG-motif containing proteins represent one of the major subsets of RNA-binding proteins characterized by the presence of RGG/RG repeats. These proteins have been associated with a wide ... -
Elucidating the mechanism of interaction of Salmonella with plants
Salmonella, is an established pathogen of members of the kingdom Animalia. Its principal species S. enterica serovars Typhi, Paratyphi and Typhimurium can cause various diseases ranging from typhoid fever to gastroenteritis ... -
Elucidating the role of carbon metabolism genes chiA and yjiY in Salmonella pathogenesis.
Salmonella is a foodborne pathogen that causes debilitating enteric diseases in a wide range of hosts. While Salmonella Typhimurium causes self-limiting gastroenteritis in human beings, Salmonella Typhi causes typhoid fever ... -
Elucidating the Role of Cyclic GMP in Diarrhoea and Intestinal Inflammation
Cyclic guanosine 3’,5’-monophosphate (cGMP) performs a wide range of functions in various cell types and tissues. The cellular levels of cGMP are maintained by the enzymatic conversion of guanosine 5’-triphosphate (GTP) ... -
Elucidating the Role of miR-617 in Oral Squamous Cell Carcinoma Pathogenesis
Oral Squamous Cell Carcinoma (OSCC) or oral cancer is the malignancy of the epithelial lining of the oral cavity. It is the leading cause of cancer-related mortality in Indian males and despite technological advancements, ... -
Elucidating the Role of MsRbpA in Rifampicin Tolerance and Transcription Regulation of Mycobacterium Smegmatis
(2018-04-12)RNA polymerase binding protein A (RbpA) was first discovered as a RNA polymerase binding protein from Streptomyces. coelicolor. It was shown to cause rifampicin tolerance to RNA polymerase in vitro and leads to basal level ...