Browsing Division of Biological Sciences by Title
Now showing items 117-136 of 1514
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Characterization of XRN2-mediated microRNA turnover mechanism and its pathophysiological significance in eukaryotes
MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that are extensively involved in the posttranscriptional regulation of gene expression in eukaryotes. Comprehensive studies on miRNA expression and function have ... -
Characterizing the link between dynamics and function in proteins that violate the structure-function paradigm
The structure-function paradigm states that the three-dimensional structure of a protein is dictated by its amino acid sequence, which influences its function. However, this paradigm fails to explain the behaviour of ... -
Characterizing the role of claudins in C. elegans neurons
Cell adhesion molecules (CAMs) play important roles in neurons, contributing to nervous system development, synapse formation and plasticity. A subset of CAMs, Claudins, known for their roles at tight junctions, remain ... -
Characterizing the viral factors and host determinants that control Dengue virus infection and pathogenesis
Background – Dengue virus is a mosquito-borne flavivirus that is the causative agent for dengue fever, which progresses to dengue shock syndrome in many patients. It is estimated that around 390 million dengue infections ... -
Chemical and biological investigation on antibiotic principles of Garcinia Morella
The thesis comprises two parts. Part I describes in four chapters the isolation and chemistry of some of the constituents, and Part II describes their biological properties. Part I. Chapter I: Isolation and Properties of ... -
Chemical and biological studies on some natural and synthetic antimicrobial substances
The eventful developments of chemotherapy and the growth in our concepts of the treatment of infective diseases, from Ehrlich to the present day, have been briefly traced, stressing the outstanding practical achievements. ... -
Chimeric Virus Like Particles as Nanocarriers for Antibody Delivery in Mammalian Cells & Role of Groundnut Bud Necrosis Virus NSs in Viral Life Cycle
(2018-08-02)Knowledge of the dissociation constants of the ionizable protons of weak acids in aqueous media is of fundamental importance in many areas of chemistry and biochemistry. The pKa value, or equilibrium dissociation constant, ... -
Chlorophenoxyisobutyrate : an approach to the study of mitochondrial energy transduction
Abstract not available -
Cholinergic-receptor-independent modulation of intrinsic properties of subicular neurons through inhibition of hyperpolarization-activated cyclic nucleotide-gated channels
Acetylcholine release is vital in tuning the hippocampal theta oscillations. Subiculum, the output region of the hippocampus endowed with different neuronal subtypes, also generates theta oscillations during arousal and ... -
Circuit mechanisms of itch modulation: from physiology to pathology
Itch is a distinct somatosensation, evoked by chemical and mechanical pruritogens or psychosomatic factors. It detects harmful sensory stimuli and triggers scratching to remove irritants from the skin. However, chronic ... -
Climate Change Mitigation And Adaptation In Indian Forests
(2014-10-10)Research leading to this thesis aims to assess the policy relevant mitigation potential of Indian forests as well as aims to assess the impact of climate change on carbon stocks, vegetation boundary shifts, Net Primary ... -
Climate-Growth Relationships of West Himalayan Fir (Abies pindrow) along an Altitudinal Gradient in Northwestern Himalaya
Climate change which includes an increase in temperature, changes in precipitation, retreating of glaciers, has a significant impact on ecosystem dynamics and the social communities. High mountains around the globe are ... -
Cloning and Expression of a Diagnostic Antigen for Invasive Amoebiasis
(Indian Institute of Science, 2005-04-29)A crude extract of axenically grown amoebae was used as antigen in order to develop an AB microELISA for the detection and quantitation of E. histolytica-specific IgG antibodies. This ELISA was used to screen individual ... -
Collective escape dynamics of fission-fusion groups in the wild
Collective movement is a fundamental process affecting the survival and reproductive success of group-living animals. Many of the hypothesized benefits of grouping such as predation evasion and foraging efficiency may ... -
Colony Founding And The Evolution Of Eusociality In Primitively Eusocial Wasp, Ropalidia Marginata
(Indian Institute of Science, 2005-08-08)Many animals live in societies of varying degrees of organization. Some individuals in these societies seem to sacrifice their own fitness to increase the fitness of some others. Understanding the forces that mould the ... -
Compact alwin grammar and algorithms for computer coding of organic chemical structures
Abstract not available -
Comparative analyses of homologous protein sequences and structures : Inference on protein evolution
Proteins are linear polymers composed of 20 different amino acid residues and can fold into complex three-dimensional (3D) structures. For a given protein, the information required to fold into a precise 3D structure is ... -
Comparative analysis of functions of proteins encoded in the genomes of human and chimpanzee
Abstract not available -
Comparative evaluation of retrograde regulatory proteins (Rtg1p, Rtg2p, and Rtg3p) of Saccharomyces cerevisiae and Pichia pastoris and identification of P. pastoris RtgXp as a novel regulator of multiple metabolic pathways
Our work demonstrates for the first time that PpRtgXp, a basic, helix-loop-helix (bHLH) protein, is a global regulator of carbon metabolism. PpRtgXp constitutively localizes inside the nucleus. Despite lacking the C-terminal ...