Browsing Division of Biological Sciences by Title
Now showing items 1005-1024 of 1513
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Saccharomyces cerevisiae meiosis-specific hop1 protein and its putative zinc-finger motif promote synapsis between double-stranded DNA helices : a role for guanine quartets in ininterstitial pairing
Meiosis is an evolutionarily conserved biological process that allows genetic exchange between paternal and maternal genomes in all sexually reproducing species. The hallmark features of meiosis include pairing of homologous ... -
Salmonella Pathogenesis in Dendritic Cells : Stealthy Approach Against Adaptive Immune Response
Synopsis of work done by Mayuri Gogoi (SR No. 10-09-00-10-31-11-1-08534) for the award of Ph.D. degree in the Faculty of Science, Indian Institute of Science, Bangalore, India. Thesis title: Salmonella pathogenesis in ... -
Scanning mutagenesis studies of HIV-1 Env immunogenicity and structure
Human Immunodeficiency Virus type 1 (HIV-1) is the etiological agent of Acquired Immunodeficiency Syndrome (AIDS). AIDS is a global pandemic with 36.7 million people living with HIV-1 all over the world and approximately ... -
Secondary Structures in Proteins : Identification and Analyses
(2018-07-12)Proteins are large biomolecules consisting of one or more long chains of amino acid residues. They perform a vast array of functions within living organisms. In this thesis, we present analyses of different secondary ... -
Seed Dispersal In The Tropical Dry Forests Of Mudumalai, Southern India
(2011-06-30)Plants depend on a wide variety of vectors, both biotic and abiotic, to move their seeds to locations away from parent plants. The stages between seed production and seedling establishment in the plant life cycle are under ... -
Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution
(2010-09-30)Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ... -
Sensory Ecology Of Acoustic Communication In The Tropical Bushcricket Genus Mecopoda : Mechanisms And Evolution Of Synchrony
(2009-07-10)In this thesis, I characterise five species of the bushcricket genus Mecopoda with respect to their acoustic signals and morphology and investigate the phenomenon of acoustic synchrony in one of these five species: Mecopoda ... -
Sequence Analysis And Design Of Immunogens From The Stem Domain Of Influenza Hemagglutinin
(2013-07-10)Influenza is an important respiratory pathogen that infects several million people each year. Currently available flu vaccines have to be updated regularly in order to be effective as the virus changes its composition by ... -
Sequence And Structural Determinants of Helices in Membrane Proteins
(2017-09-23)Membrane proteins roughly constitute 30% of open reading frames in a genome and form 70% of current drug targets. They are classified as integral, peripheral membrane proteins and polypeptide toxins. α-helices and β -strands ... -
Sequence specifist in protein nuclies acid interaction
The interaction specificities of various dipeptides, NH –CH –CO–NH–CH(R)–COO ; (R = H, Leu, Tyr, Ser, Asp, Met, Lys, His) with various mononucleotides have been determined from measurements of nucleotide induced changes ... -
Sexual Selection On Elephant Tusks
(2017-06-12)Darwin was troubled by elaborate male traits observed in many species that are seemingly maladaptive for survival, the peacock’s tail being the most iconic of all. He wrote "The sight of a feather in a peacock’s tail, ... -
Shared and distinct mechanisms of saccade preparation, external and internal attention
Everyday activities – like reading an email, watching a football match, scrolling through social media, or window-shopping – all involve quickly scanning complex visual scenes using rapid eye movements called “saccades.” ... -
Significance of multiple copies of initiator tRNA genes in Escherichia Coli
E. coli has four copies of initiator tRNA genes-the highest number known in any eubacterium. Among prototrophs, strains carrying four initiator tRNA genes have a growth advantage over strains carrying three initiator tRNA ... -
Simple repetitive DNA sequences, unusual DNA structures and transcriptional control
With the progressive understanding of genome structure, organization, and sequence information, it has become evident that repetitive DNA sequences form a significant and substantial fraction of eukaryotic genomes. These ... -
Single-channel studies on human TREK-1 (hTREK-1) channels to intracellular ischemia related factors
TREK-1, a member of the two-pore domain family of potassium channels, majorly contributes to the maintenance of resting membrane potential of a cell and has been reported to respond to ischemic levels of intracellular ... -
Small Heat Shock Proteins from Bacteria and a Bacteriophage
Proteins can unfold during heat and other types of stress and tend to aggregate with subsequent loss of function. This event is prevented by small Heat Shock Proteins (sHSPs) acting as molecular chaperones. sHSPs do not ... -
Small Heat Shock Proteins from Oryza Sativa and Salmonella Enterica
(2018-05-09)Small heat shock proteins (sHSPs) are a ubiquitous family of molecular chaperones that play a vital role in maintaining protein homeostasis in cells. They are the first line of defence against the detrimental effects of ... -
Social Organisation And Cooperation In Genetically Mixed Colonies Of The Primitively Eusocial Wasp, Ropalidia Marginata
(Indian Institute of Science, 2005-08-05)Altruism in its extreme form is seen in social insects where most individuals give up their own reproduction and work to rear the offspring of their queen. The origin and evolution of such sterile worker castes remains a ... -
Soil microorganisms and biogeochemical cycles in a grazing ecosystem: interactions between producers, consumers, and decomposers
Microorganisms are the unseen majority that determines ecosystem processes, they perform biogeochemical functions that translate into essential services, and regulate global climate. In grazing ecosystems, which represent ... -
Solution NMR studies of a potent subtilisin inhibitor from Budgett’s frog and the catalytic subunit of AHAS
This thesis involves a detailed structural study of two molecular systems, a small disulfide-rich peptide LL-TIL and a large catalytic subunit of AHAS. Subtilisin inhibitors play an important role in fighting against ...