Browsing Division of Biological Sciences by Title
Now showing items 1276-1295 of 1425
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T Cell Epitopes Of PE And PPE Family Of Proteins Of Mycobacterium Tuberculosis And Analysis Of Their Vaccine Potential
(2010-03-09)One-third of the world’s population is latently infected with Mycobacterium tuberculosis, which causes over 2 million deaths every year. The current live attenuated vaccine, Bacille Calmette-Guerin (BCG), protects against ... -
Target Genes and Pathways Regulated by OsMADSI during Rice Floret Specification and Development
(2018-04-12)In angiosperms, specialized reproductive structures are borne in flowers to ensure their reproductive success. After the vegetative growth, plants undergo reproductive phase change to produce flowers. Floral meristems (FMs) ... -
Targeting Gonadotropins to the Dendritic Cells : A Novel Strategy for Animal Immunocontraceptive Vaccine
(2018-05-09)Contraception through a vaccine has been a very attractive proposition and several attempts were made in the past. To achieve contraception through immunological means, several points need to be considered. First, the ... -
Targeting RAD51C Pathological Mutants by Synthetic Lethality and Extended Functions of RAD51C/XRCC3 in Mitochondrial Genome Maintenance
To counteract the potentially calamitous effects of genomic instability in the form of double-strand breaks (DSBs), cells have evolved with two major mechanisms. First, DNA non¬homologous end joining (NHEJ) which requires ... -
Targeting The CD4 Biniding Site In HIV-1 Immunogen Design
(2016-11-15)Over three decades have passed since the discovery of HIV-1, yet an AIDS vaccine remains elusive. The envelope glycoprotein of HIV-1 gp120, is the most exposed protein on the viral surface and thus serves as an important ... -
Temporal patterns of neural activity governing spatial representation in the hippocampus
Space is a fundamental substrate for animal interactions with the external world. The hippocampus, a region deep within the temporal lobe of mammalian brains, is a multisensory structure that has been heavily implicated ... -
Territorial and mating strategies of males in a lekking population of blackbuck Antilope cervicapra
Territoriality associated with lek-mating systems is unique in that males defend small, heavily clustered territories that lack resources usually thought to attract females, such as food and water. Females visit these male ... -
The Modes of binding of carbohydrates to concanavalin a : a computer modelling approach
Concanavalin A (Con A), the carbohydrate?binding protein (lectin) originally isolated from the jack bean (Canavalia ensiformis), specifically binds to carbohydrates containing ??D?mannose and ??D?glucose residues in ... -
The Reversible unfolding of the Tetrameric serine hydroxymethyltransferase
(1) The discovery, just over 3 decades ago by Anfinsen and coworkers, that proteins can be refolded under in vitro conditions, suggested that the information necessary for proper folding resides in the primary sequence of ... -
Theoretical investigation on the geminal proton-carnon-13 Coupling constants
It has been concluded from the present study that the geminal proton coupling of carboxyl (carbonyl) carbon-13 has an angular dependence of the form: A+Bcos?2?A + B \cos^2 \thetaA+Bcos2? based on the relative orientation ... -
Theoretical studies on peptide conformation
It is now well established that the biological activities of polypeptides and proteins are intimately connected with their 3-dimensional structures and so the determinations of these provide insight into their mode of ... -
Theoretical studies on the conformation and mode of binding of some inhibitors of thermolysin
Abstract not available -
Theoretical studies on the influence of exo-anomeric effect,geometry of sugar linkage on the unperturbed dimensions of polysaccharides
Recently, application of conformational energy calculations in the field of carbohydrates has led to a number of interesting and important results. A few attempts have also been made to compute the unperturbed dimensions ... -
Theoretical, Spectroscopic and crystallographic studies on peptide stuctures
The results reported in this part of the thesis—namely those on formamide, N-methylformamide (including isotopically enriched species), and N-methylacetamide—show significant non?planar distortions around the nitrogen atom. ... -
Theoritical studies on the molecular structure of collagen and related polypeptides
In Section 1.5, it is seen that hydroxyproline residues can give added stability to the collagen fibers by forming both intra- as well as intermolecular hydrogen bonds involving the ?-hydroxyl group. 2.4 Conclusion It ... -
Thermodynamic Characterization Of Wild Type And Mutants Of The E.coli Periplasmic Binding Proteins LBP, LIVBP, MBP And RBP
(2009-03-13)Native states of globular proteins typically show stabilization in the range of 5 to 15 kcal/mol with respect to their unfolded states. There has been a considerable progress in the area of protein stability and folding ...