Browsing Microbiology and Cell Biology (MCB) by Title
Now showing items 225-244 of 292
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Studies on aminoacyl-TRNA synthestases from mycobacteria
As a part of the investigations on “Genetic coding and protein synthesis in Mycobacteria”, studies on aminoacyl?tRNA synthetases have been undertaken. Valyl?tRNA synthetase from M. smegmatis has been purified by conventional ... -
Studies on Arginyl- and lysyl- tRNA synthetases from mycobcterium smegmatis
STUDIES ON ARGINYL- AND LYSYL-tRNA SYNTHETASES FROM MYCOBACTERIUM SMEGMATIS Aminoacyl-tRNA synthetases are a family of enzymes which play an important role in protein synthesis. These enzymes catalyze the esterification ... -
Studies On DNA Gyrase From Mycobacteria : Insights Into Its Mechanism Of Action And Elucidation Of Its Interaction With The Transcription Machinery
(2010-09-30)Packaging of genomic DNA by proteins and super coiling into chromatin and chromatin-like structures (in bacteria) influences nearly all nuclear process such as replication, transcription, repair, and recombination. A ... -
Studies on exosomal microRNAs and proteins associated with Hepatitis C and Dengue virus induced pathogenesis
Studies on the exosomal microRNAs and proteins associated with Hepatitis C and Dengue virus-induced pathogenesis. Hepatitis C virus and Dengue virus are the group of positive-strand RNA viruses belonging to the family ... -
Studies On Human Sex Chromosomes And Sex Determination
(2014-09-15) -
Studies On Initiator tRNA Selection On The Ribosomes In Escherichia Coli
(2009-05-06)The studies reported in this thesis address the aspects of initiator tRNA selection in Escherichia Coli. A summary of the relevant literature discussing the process of ptotein biosynthesis in general and initiator tRNA ... -
Studies on Interactions between ARE Binding Proteins and Splicing Factors and their Role in Altered Splicing of PDGF-B ORF
(2018-03-03)Pre-mRNA splicing is an important level in posttranscriptional gene regulation that is essential for accurate protein synthesis and generating protein diversity. The abundance of cryptic splice sites and long intronic DNA ... -
Studies on Molecular Targets and Pathways Regulated by Rice RFL for Flowering Transition and Panicle Development
(2017-11-28)LFY of Arabidopsis is a member of a unique plant specific transcription factor family. It is involved in giving meristem a determinate floral fate by the activation of floral organ identity genes and preventing inflorescence ... -
Studies on Nudix hydrolase proteins and crosstalk between DNA repair pathways
Mycobacterium tuberculosis, the causative agent of tuberculosis, has become a global health concern. This calls for a dire need to understand various aspects of mycobacterial physiology in order to design better strategies ... -
Studies On Phosphorylation And Oligomerization Of Rotavirus Nonstructural Protein 5 (NSP5) And Cellular Pathways That Regulate Virus Replication
(2016-04-28)Rotavirus is one of the leading etiological agents of gastroenteritis in young of many species including humans worldwide and is responsible for about 600,000 infant deaths per annum. Rotavirus belongs to the Reoviridae ... -
Studies on regulation of transcription and translation during differentiation of nicotians.... cultures
The resumption of development and differentiation in callus cultures is brought about by phytohormones. To provide insight into some of the molecular events associated with this differentiation process, the present study ... -
Studies on Rotavirus Nonstructural Protein 5 (NSP5)
Rotavirus is the most important agent of viral gastroenteritis in humans and animals and is responsible for about 600,000 deaths per annum. Most of these deaths occur in the developing countries and India is estimated to ... -
Studies On Saccharomyces Cerevisiae RNA Polymerase II Subunit Rpb7 And Its Eukaryotic Orthologs
(2010-06-03)Saccharomyces cerevisiae is an excellent experimental model organism to study various biological processes owing to its versatile genetics, biochemistry, and standard laboratory conditions. S. cerevisiae shows distinct ... -
Studies on the development of behaviour in the asiatic elephant
The present study focuses on the development of behaviour during the first year of age in the calf of the Asiatic elephant. The elephant calf can be classified as a defended follower. It is completely dependent until the ... -
Studies On The Mechanism Of Uracil Excision Repair In Escherichia Coli And Structure-Function Relationship Of Single Stranded DNA Binding Proteins From Escherichia Coli And Mycobacterium Tuberculosis
(2014-12-11)To maintain the genomic integrity, cell has evolved various DNA repair pathways. Base Excision Repair pathway (BER) is one such DNA repair pathway which is dedicated to protect DNA from small lesions such as oxidation, ... -
Studies on the mechanisms of action and the physiological roles of MutT1 in mycobacteria
Mycobacterium tuberculosis (Mtb), a pathogenic bacterium, thrives and proliferates inside host macrophages, encountering a high level of reactive oxygen species and reactive nitrogen intermediates which is generated by the ... -
Studies on the mode of inhibition of avian myeloblastosis virus multipulication by cupric isonicotinic acid hydrazide complex
The primary objectives of cancer chemotherapy programs include the screening and evaluation of new chemicals and natural products in experimental systems for their anticancer activity and the recommendation of new anticancer ... -
Studies on the molecular mechanism of action of 5- fluororacil : interaction of amino acyl-tRNA synthetases with 5- fluororacil substituted transfer RNA from rat liver
FUra, a potent anticancer agent, gets incorporated into tRNA and affects the efficiency of adapter functions of tRNA. Incorporation of FUra, as a first step, interferes with the initial processes of aminoacylation. The ... -
Studies on the molecular mechanism of action of 5- Fluorouracil: altered functions of 5- Fluorouracil substituted transfer RNA …
Among the various anticancer drugs available for clinical use, 5?fluorouracil (FUra) occupies a distinct position. It is used in the treatment of several cancers either singly or in combination with other anticancer agents. ...