Browsing Microbiology and Cell Biology (MCB) by Title
Now showing items 121-140 of 253
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Metabolism Of Queuosine, A Modified Nucleoside, In Escherichia Coli And Caenorhabditis Elegans And Dual Function Of Bovine Mitochondrial Initiation Factor 2 As Initiation Factors 1 And 2 In Escherichia Coli
(2009-06-29)The studies reported in this thesis address firstly, the biology of a modified nucleoside, Queuosine (Q) and secondly, the properties of mitochondrial translation initiation factor 2. A summary of the relevant literature ... -
miRNA-based regulation of Coxsackievirus B3 replication and pathogenesis
Coxsackievirus B3 (CVB3) is a single-stranded, positive-sense RNA virus known to cause acute myocarditis, pancreatitis, and aseptic meningitis. In many cases, the long-term impact of CVB3 infection-induced cell death ... -
Modulation Of Bacterial Pathogenesis By Curcumin
(2014-07-03)Foodborne diseases are one among the diseases with high morbidity and mortality rate. The concern is raised with the emergence of pathogenic strains that are resistant to the available set of antibiotics. Conventional ... -
The Molecular Basis for the Differential Antibiotic Susceptibility of Mycobacterial Subpopulations
Mycobacterial populations have evolved various strategies to withstand diverse stress conditions in the environment. One among these strategies is maintenance of phenotypic heterogeneity, in terms of cell morphology, ... -
Molecular basis of attenuation of the live attenuated Japanese encephalitis virus vaccine SA14-14-2
Japanese encephalitis virus is a member of Flaviviridae family. Flaviviridae family has four genera which comprises of Flavivirus, Pestivirus, Hepacivirus and Pegivirus. The global burden of disease caused by these viruses ... -
Molecular Characterisation Of Mycobacterium Tuberculosis Fic Protein And Its Gene And Identification And Characterisation Of A Novel Functional Interaction Between FtsZ And NDK in Mycobacteria
(2016-04-29)Living organisms employ different kinds of mechanisms, to regulate the functions of genes or their products, which may help in maintaining homeostasis inside the cell or may help in fighting hostile environment in the case ... -
Molecular Characterisation Of The ATP Binding Cassette (ABC) Transporter Type FtsE And FtsX Proteins Of Mycobacterium Tuberculosis
(2008-09-30)Mycobacterium tuberculosis, the principal causative agent of tuberculosis (TB) in humans, is considered to be a successful pathogen owing to the elicitation of multidrug resistance, ability to survive inside macrophage ... -
Molecular Genetic Analysis Of Flower Development In Rice
(2011-12-12) -
Molecular Genetic Analysis of Trichome Development in Arabidopsis thaliana
Several mutants with aberrant trichome patterning and differentiation are known in Arabidopsis. The genes involved in these processes code for proteins with diverse functions such as transcription, protein degradation, ... -
Molecular Genetic Studies On Pre-mRNA Splicing Factors Of Fission And Budding Yeasts
(2010-10-05)Nuclear pre-mRNA splicing proceeds via two mechanistically conserved consecutive trans-esterification reactions catalyzed by the spliceosome. The ordered coalescence of spliceosomal snRNPs and splicing factors on the ... -
Molecular pathways governing maturation and decay of precursor piRNAs in Caenorhabditis elegans
Piwi-interacting RNAs (piRNAs) are an animal-specific class of germline-enriched small non-coding RNAs that play a crucial role in germline development and fertility in diverse organisms. In Caenorhabditis elegans (C. ... -
Mycobacterial topoisomerases: insights into structure, mechanism and function
DNA encounters topological constraints during essential cellular processes such as replication, transcription, and chromosome segregation. To ensure facile execution of these processes, a ubiquitous class of enzymes known ... -
New Active Site Fold And The Role Of Metal Ions In Structure Function Relationship Of A Promiscuous Endonuclease - R.KpnI
(2010-07-08)Bacteria employ survival strategies to protect themselves against foreign invaders, including bacteriophages. The ‘immune system’ of bacteria relies mostly on restriction-modification (R-M) systems. The primary role of R-M ... -
Notch1-Induced Survival Signaling And Its Implications In Cancer Therapeutics
(2009-04-15)Notch receptors and ligands are type I transmembrane proteins that regulate development and differentiation during cell-cell contact. There are four Notch receptor homologues and five notch ligands, identified in humans ... -
Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions
Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, ... -
Panoramic View of RNA Binding Proteins (RBPs) in Glioblastoma : IMP3, an RBP, is Essential for Glioma Stem-like Cell Maintenance
Gliomas are primary brain tumors in adults that are believed to originate from different types of glial cells. Central nervous system gliomas pose particularly difficult problems because of their tendency towards malignancy, ... -
Physiological Importance Of DNA Repair In Mycobacteria
(2013-01-16)