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    • Browsing Microbiology and Cell Biology (MCB) by Title
    •   etd@IISc
    • Division of Biological Sciences
    • Microbiology and Cell Biology (MCB)
    • Browsing Microbiology and Cell Biology (MCB) by Title
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    Browsing Microbiology and Cell Biology (MCB) by Title

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      • The Molecular Basis for the Differential Antibiotic Susceptibility of Mycobacterial Subpopulations 

        Sharan, Deepti
        Mycobacterial populations have evolved various strategies to withstand diverse stress conditions in the environment. One among these strategies is maintenance of phenotypic heterogeneity, in terms of cell morphology, ...
      • Molecular basis of attenuation of the live attenuated Japanese encephalitis virus vaccine SA14-14-2 

        Kumar, Saurabh
        Japanese encephalitis virus is a member of Flaviviridae family. Flaviviridae family has four genera which comprises of Flavivirus, Pestivirus, Hepacivirus and Pegivirus. The global burden of disease caused by these viruses ...
      • Molecular Characterisation Of Mycobacterium Tuberculosis Fic Protein And Its Gene And Identification And Characterisation Of A Novel Functional Interaction Between FtsZ And NDK in Mycobacteria 

        Mishra, Saurabh (2016-04-29)
        Living organisms employ different kinds of mechanisms, to regulate the functions of genes or their products, which may help in maintaining homeostasis inside the cell or may help in fighting hostile environment in the case ...
      • Molecular Characterisation Of The ATP Binding Cassette (ABC) Transporter Type FtsE And FtsX Proteins Of Mycobacterium Tuberculosis 

        Mir, Mushtaq Ahmad (2008-09-30)
        Mycobacterium tuberculosis, the principal causative agent of tuberculosis (TB) in humans, is considered to be a successful pathogen owing to the elicitation of multidrug resistance, ability to survive inside macrophage ...
      • Molecular Genetic Analysis Of Flower Development In Rice 

        Kushalappa, M Kumuda (2011-12-12)
      • Molecular Genetic Analysis of Trichome Development in Arabidopsis thaliana 

        Vijaya Lakshmi Vadde, B
        Several mutants with aberrant trichome patterning and differentiation are known in Arabidopsis. The genes involved in these processes code for proteins with diverse functions such as transcription, protein degradation, ...
      • Molecular Genetic Studies On Pre-mRNA Splicing Factors Of Fission And Budding Yeasts 

        Khandelia, Piyush (2010-10-05)
        Nuclear pre-mRNA splicing proceeds via two mechanistically conserved consecutive trans-esterification reactions catalyzed by the spliceosome. The ordered coalescence of spliceosomal snRNPs and splicing factors on the ...
      • Molecular pathways governing maturation and decay of precursor piRNAs in Caenorhabditis elegans 

        Samajdar, Aniruddha
        Piwi-interacting RNAs (piRNAs) are an animal-specific class of germline-enriched small non-coding RNAs that play a crucial role in germline development and fertility in diverse organisms. In Caenorhabditis elegans (C. ...
      • New Active Site Fold And The Role Of Metal Ions In Structure Function Relationship Of A Promiscuous Endonuclease - R.KpnI 

        Saravanan, M (2010-07-08)
        Bacteria employ survival strategies to protect themselves against foreign invaders, including bacteriophages. The ‘immune system’ of bacteria relies mostly on restriction-modification (R-M) systems. The primary role of R-M ...
      • Notch1-Induced Survival Signaling And Its Implications In Cancer Therapeutics 

        Mungamuri, Sathish Kumar (2009-04-15)
        Notch receptors and ligands are type I transmembrane proteins that regulate development and differentiation during cell-cell contact. There are four Notch receptor homologues and five notch ligands, identified in humans ...
      • A Novel Antigen From Mycobacterium Bovis BCG : Biochemical And Immunological Studies 

        Pawar, Santosh N (2011-12-12)
      • Nucleoid-associated Proteins of Mycobacterium tuberculosis : Insights into their Functions 

        Ghosh, Soumitra
        Bacteria face the challenging task of compacting their chromosomes to accommodate them in a small cytoplasmic volume and at the same time maintaining the nucleoids in a highly organized and dynamic state for transcription, ...
      • Panoramic View of RNA Binding Proteins (RBPs) in Glioblastoma : IMP3, an RBP, is Essential for Glioma Stem-like Cell Maintenance 

        Bhargava, Shruti
        Gliomas are primary brain tumors in adults that are believed to originate from different types of glial cells. Central nervous system gliomas pose particularly difficult problems because of their tendency towards malignancy, ...
      • Perpetuation Of T cell Memory : A Role For Anti-Idiotypic T Cells 

        Lal, Girdhari (2013-08-13)
      • Physiological Importance Of DNA Repair In Mycobacteria 

        Kurthkoti, Krishna (2013-01-16)
      • Physiological Role of Arr, an ADP-ribosyltransferase in Mycobacterium smegmatis 

        Agrawal, Priyanka
        The studies reported in this thesis address the physiological role of an antibiotic resistance gene arr, followed by establishment of the arr knockout strains (generated during the investigation) for drug testing and ...
      • Physiological Role of Folate Dehydrogenase in One Carbon Metabolism of Escherichia Coli 

        Aluri, Srinivas (2018-06-08)
        Thesis addresses the physiological role of formyl tetrahydrofolate synthetase (Fhs) and bifunctional folate dehydrogenase (FolD) in folate mediated one carbon metabolism in bacteria. Thesis consists of 5 chapters. First ...
      • Post translational modification and DNA binding studies with two nucleoid associated proteins of Mycobacterium tuberculosis 

        Anand, Chinmay
        Genome in prokaryotes is found in a small confinement called nucleoid. The nucleoid compaction is brought about by the combined action of topoisomerases and Nucleoid associated proteins (NAPs). Topoisomerases maintain ...
      • PP2A-phosphatase and Polo-like kinase 1 regulates spindle positioning by orchestrating the cortical levels of the dynein adaptor NuMA 

        Keshri, Riya
        The mitotic spindle is a microtubule-based diamond shape structure that captures chromosomes and facilitates their segregation during anaphase. Proper positioning of the mitotic spindle is critical for defining the ...
      • Probing the Splicing and Enzymatic Function of Fission Yeast Prp16 – A DEAD Box RNA Helicase 

        Sharma, Amit Kumar
        Nuclear pre-mRNA splicing occurs at precisely conserved sequence elements at and around the splice sites which result in ligation of exons and release of intron as lariat. The Schizosaccharomyces pombe genome is an apt ...

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