Browsing Microbiology and Cell Biology (MCB) by Title
Now showing items 189-208 of 292
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Rice transcription factors OsMADS2 and OsMADS4 regulate floret organ development: Deciphering their gene targets, traits and functions related to their unequal genetic redundancy
Organs in modern dicot flowers are positioned in concentric rings (whorls). The outermost whorl has green protective sepals, internal to which are showy petals, and the reproductive stamen and carpel whorls. Florets of ... -
Rinderpest Virus Transcription : Functional Dissection Of Viral RNA Polymerase And Role Of Host Factor Ebp1 In Virus Multiplication
(2009-11-23)Rinderpest virus (RPV) belongs to the order Mononegavirale which comprises non segmented negative sense RNA viruses including human pathogens such as Measles, Ebola and Marburg virus. RPV is the causative agent of Rinderpest ... -
RNA polymerases in micor-sporum canis
Fungi are an important group of microorganisms which reproduce by means of specialized cells called spores. These spores are generally considered as a quiescent stage in their life cycle. However, on a suitable substrate, ... -
Role of conserved features of initiator tRNA and ribosome heterogeneity in translation initiation in Escherichia coli
Translation is one of the fundamental and core cellular processes catalysed by a ribonucleoprotein complex called ribosome. The process involves four major steps: initiation, elongation, termination and recycling. Initiation ... -
Role of DNA Methylation in Glioblastoma Development
(2018-04-11)Glioblastoma (GBM) is the most common and malignant of the glial tumors. These tumors may develop from lower-grade astrocytomas (diffuse astrocytoma; grade II or anaplastic astrocytoma; grade III) through a progressive ... -
Role of Hydrogen Sulfide Gas in Modulating HIV-1 Latency and Reactivation
Human Immunodeficiency Virus 1 (HIV-1) remains a global public health threat, claiming 690 thousand people’s lives in 2020 and causing 1.5 million new infections. The advent of combinatorial antiretroviral therapy (ART) ... -
Role Of Idiotypic Anti-Idiotypic Network In The Sustenance Of Immunological Memory
(2009-05-25)Living amidst a milieu of pathogenic organisms, vertebrates are in constant threat of contracting one or the other disease. As a mechanism of protection against such ‘invasions’, the vertebrate immune system has evolved ... -
The Role of Initiation Factor 3 : Insights from E. Coli, Mitochondria and Mycoplasma
(2018-01-07)The process of translation initiation is the most highly regulated step of protein synthesis. In bacteria, three initiation factors (IF1, IF2 and IF3) play crucial roles during initiation. IF3 acts as an anti-association ... -
Role Of Matrix Protein Of Rinderpest Virus In Viral Morphogenesis
(2008-10-20)Rinderpest virus is an enveloped Nonsegmented Negative Stranded RNA Virus (NNSV) belonging to the genus Morbillivirus in the Family Paramyxoviridae and the causative organism for “cattle plague”. The virion has a transport ... -
Role of PARP16 in Cardiac Remodeling
Role of PARP16 in cardiac remodeling Cardiac remodeling, a complex process involving alterations in myocardial structure and function, is a major contributor to heart failure. While physiological remodeling supports cardiac ... -
Role of Queuosine in Codon-Anticodon Interaction
The speed and accuracy of the process of protein synthesis is very high. The major step at which the fidelity of translation is governed is at the step of codon?anticodon pairing. An erroneous codon?anticodon pairing can ... -
The role of Rv1860 from M. tuberculosis in modulating the host immune response
Tuberculosis continues to prevail as the major cause of mortality from any single pathogen around the world, despite implementation of control programs and the availability of effective drugs and the vaccine BCG. Mycobacterium ... -
Role of Sirt2 in Stress-induced Muscle Atrophy
Skeletal muscle is one of the essential organs in our body, responsible for various functions such as locomotion, transport, protein storage, and thermoregulation. Under certain pathological conditions, there is a reduction ... -
ROLE OF SIRT6 AND PARP-1 IN MUSCLE HOMEOSTASIS
Sirtuins and PARPs are stress responsive family of proteins regulating genome instability, inflammation, aging-related diseases and energy metabolism. Both sirtuins and PARPs are NAD+ enzymes with deacetylase and ADP-ribose ... -
Role of SIRT6 in Myofibroblast Cell Death
(2018-01-10)Cardiovascular diseases are one of the leading causes of mortality. A common denominator across most of the cardiovascular diseases like diabetic cardiomyopathy, hypertrophic cardiomyopathy, myocardial infarction and dilated ... -
Role of SIRT6 in the Regulation of Glucose Metabolism and Fatty Acid Uptake in Heart
The adult heart heavily relies on fatty acid for most of its energy supplies. The heart derives most of the fatty acid from circulation. Hence, fatty acid uptake forms a crucial step in cardiac metabolism. Studies have ... -
Role of SIRT6 in the regulation of mTOR signalling and global protein synthesis
Cells are constantly engaged in the process of making and breaking proteins in a highly organized manner. However, protein synthesis is an energetically expensive process and often competes with other cellular repair and ... -
Role of Sirtuin 2 in the development of tissue fibrosis
Wound healing is a crucial physiological process required for the healthy lifespan of an organism. Dysregulation in the process of wound healing leads to the production of excess extracellular matrix leading to fibrosis. ...