Browsing Microbiology and Cell Biology (MCB) by Title
Now showing items 101-120 of 292
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Immunological insights into Epidermal Growth Factor Receptor Signaling: Implications for host-pathogen interactions
Infectious diseases account for a large proportion of morbidity and mortality worldwide. The major global efforts lie in effectively enhancing the health span of infected individuals and more importantly, curbing infection ... -
Importance of formylation in eubacterial translation initiation
Initiation of protein synthesis in all organisms occurs with the amino acid methionine. In the case of eubacteria and eukaryotic organelles, methionine is further modified to formylmethionine by the enzyme methionyl?tRNA ... -
Improving Glioblastoma Management: A Study of Biomarkers, Tumor Microenvironment and Chemoresistance
Glioblastoma (GBM) is an aggressive form of adult brain tumors. The current standard of care includes maximal safe resection followed by concurrent chemo-radiation therapy and adjuvant chemotherapy with temozolomide. ... -
Influence Of FtsH Protease On The Medial FtsZ Ring In Escherichia Coli
(2013-07-17)FtsH is an essential AAA family Zn++ metalloprotease of Escherichia coli, possessing ATPase-dependent chaperon activity and ATP-dependent protease activity. Heat shock transcription factor Sigma32, LpxC, SecY, and bacteriophage ... -
The Influence of Glycerol and Specific Genes on the Asymmetric Cell Division in Mycobacteria
The Influence of Glycerol and Specific Genes on the Asymmetric Cell Division in Mycobacteria Submitted by Atul Pradhan (S.R. No. 03-04-00-10-11-14-1-11678) Background Information: Mycobacteria maintain heterogeneity in ... -
Influence of population bottlenecks on the evolution of sociality in synthetic life-cycle
Cooperation requires individuals to invest their resources for the benefit of others. Cooperative behaviours often involve the secretion of costly public goods, which can be exploited by spontaneous mutant cheater cells ... -
Initiation of protein synthesis : Role of the three consecutive GC base pairs in the anticodon stem of initiator tRNAs
The presence of the three consecutive GC base pairs in the anticodon stems of the initiator tRNAs (3GC base pairs) are a highly conserved and a vital feature of the initiator tRNAs in all the domains of life. How this ... -
Insights into ISWI group Chromatin Remodeler BAZ1A (bromodomain adjacent to zinc finger domain 1A): A Key Player of E2F transcription program in glioma
ISWI (Imitation Switch) family of chromatin remodeling complexes mobilize nucleosomes to control DNA accessibility, which manages various DNA template-associated processes like replication, transcription, and repair. ... -
Insights into Occurrence and Divergence of Intrinsic Terminators and Studies on Rho-Dependent Termination in Mycobacterium Tuberculosis
(2018-04-11)Two mechanisms, intrinsic and factor-dependent, have evolved for accomplishing the termination of transcription in eubacteria. In this thesis, the first chapter is an introduction to the topic that presents what is known ... -
Insights Into The Contribution Of Hfq In Salmonella Pathogenesis : Possible Role In Immune Evasion And Vaccine Development
(2014-10-07)Chapter I Introduction Salmonellae are facultative Gram-negative intracellular pathogens. Different serovars of it causes a variety of diseases in multiple hosts with different disease outcomes. Salmonella enterica serovar ... -
Insights into the Regulation of Transcription Initiation of DNA Gyrase and Role of Transcription Factor Gre from Mycobacterium tuberculosis
Genus Mycobacterium comprises a large number of species including many pathogens such as Mycobacterium leprae, Mycobacterium abscessus and Mycobacterium tuberculosis (Mtb), the last one is the causative agent of the fatal ... -
An integrative analysis of Cell Adhesion Molecules (CAMs) in Glioma: The Essential role of PTGFRN and ASTN1 in Glioma and Glioma Stem-like Cells
The central nervous system tissue contains neural stem cells which differentiate and give rise to the neurons and glial cells. The glial cells maintain neurons by providing nutrients, physical support and protection. Unlike ... -
Interaction of the TCP4 protein with other transcription factors and its effect on Arabidopsis shoot apex
The TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORs (TCP) class of proteins are plant-specific transcription factors with a non-canonical basic helix-loop-helix (bHLH) domain involved in both DNA-binding and ... -
Interactions between host cellular factors and Rotaviral viroplasmic non-structural proteins NSP5, NSP2 and their influence on virus replication
Overall, the present study demonstrates the dynamic nature of rotavirus viroplasm and how it manipulates the intracellular environment by intracellular relocalization of host proteins and their sequestration in viroplasms ... -
Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development
Title: Investigating Partners of OsMADS1 Transcription Factor and functions for some associated factors for roles in rice inflorescence and floral development The classic ABCDE model for floral organ identity show that ... -
Investigating the redox signaling mechanisms during HIV-TB co-infection
Oxidative stress has been at the forefront of HIV/AIDS-related pathophysiologies since the early days of its discovery. Overcoming HIV-1 latency, wherein, the virus remains integrated in the host chromatin, undetected and ... -
Investigating the role of an atypical dual-specificity phosphatase DUSP28 in mammalian cells
Dual-specificity phosphatases (DUSPs) belong to the protein tyrosine phosphatases (PTP) subfamily and dephosphorylate, both serine/threonine and tyrosine residues of proteins and non-protein substrates. A subgroup of ... -
Lectin from mimosa invisa L and its role in rhizobium recognition
Understanding the specificity of the legume-Rhizobium symbiosis may help in improving biological nitrogen fixation in several ways. The causes for this specificity have been studied in only a few systems like clover, ... -
Lip Y, The PE Family Triacylglycerol Hydrolase From Mycobacterium Tuberculosis : Functional Role Of The PE Domain And Immunogenicity
(2010-10-28)More human lives have been lost to tuberculosis than to any other disease and despite the availability of effective short course chemotherapy (DOTS) as well as the Bacilli Calmette Guerin (BCG) vaccine, tuberculosis continues ...