Browsing Microbiology and Cell Biology (MCB) by Title
Now showing items 1-20 of 351
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Altering DNA topology in mycobacteria: impact of perturbation of DNA gyrase on physiology and gene expression
In the current dissertation, efforts have been made to probe the in vivo role of DNA gyrase to determine its importance in the growth, physiology and gene expression in mycobacteria. In this dissertation, the role of DNA ... -
Alternate Fates of tRNAs in Initiation and Elongation
Protein synthesis in all organisms utilizes a special tRNA called the initiator tRNA. Initiator tRNAs take part in the initiation step of protein synthesis by their direct binding to the P‐site of the ribosome. The other ... -
Antimicrobial Peptides And Salmonella Pathogenesis
(2011-02-07)Chapter-I Introduction The bacteria known as Salmonellae are gram-negative, rod-shaped intracellular pathogenic bacilli that belong to the family Enterobacteriacea and causes typhoid fever. Enteric fever or typhoid ... -
B-Lactamase of mycobacterium smegmatics strains ATCC 27204 and 19979: physiological, biochemical and genetic studies.
The mechanisms of resistance to lactam antibiotics have been studied in both Gram positive and Gram negative bacteria. Lactamases play an important role in causing lactam resistance. They render the drugs antibiotically ... -
Bacterial leaf stripe disease of arecanut (arecacatechu) caused by xanthomonas areoae
The bacterial leaf stripe disease of Areca was earlier reported as caused by Xanthomonas arecae. Additional strains of the pathogen were isolated, and detailed biochemical studies were conducted and reported for the first ... -
Biochemical, Genetic and Molecular characterization of TCP3 and TCP4 transcription factors in Arabidopsis thaliana
The TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORs (TCP) family of proteins consists of plant-specific, non-canonical basic helix-loop-helix transcription factors that perform diverse developmental processes. ... -
Bombyx mori nucleopolyhedrosis virus: expression from very late promoters
The baculovirus expression system has been widely used to synthesise soluble, posttranslationally processed recombinant proteins in biologically active form. For highlevel expression of cloned foreign genes, the promoters ... -
Bombyx mori nucleopolyhedrovirus : Biotechnological applications and a model to study host-virus interactions
Bombyx mori Nucleopolyhedrovirus: Biotechnological Applications and a Model to Study Host-Virus Interactions Abstract and Synopsis Introduction Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV) can ... -
Bombyx mori nucleopolyhedrovirus : Characterization of Late Gene Expression factors,lef4 and p47
Characterization of Late Gene Expression Factors LEF4 and P47 in Bombyx mori Nucleopolyhedrovirus (BmNPV) Abstract and Synopsis Introduction A recurrent threat to the sericulture industry is the infestation of colonies ... -
Bone Morphogenesis Protein (BMP) Signaling at the Cross-roads of Host-Pathogen Interactions : Implications for Pathogenesis
(2018-06-13)Study of cell signalling pathways affected by pathogen entry comprises a fundamental aspect of understanding host-pathogen interactions. In this respect, the current study attempted to ascribe novel roles to Bone Morphogenesis ... -
Breast Cancer Susceptibility Gene 1 (BRCA1) And Breast Cancer
(2009-04-15)Breast Cancer susceptibility gene 1 (BRCA1) & Breast Cancer Breast cancer is one of the most common malignancies affecting women worldwide. About 5-10% of all cases are estimated to be familial. Mutations in the BRCA1 ... -
Carbon Starvation Genes Mediate the Cross-talk Between Metabolism and Pathogenesis of Salmonella Typhimurium
Carbon starvation genes mediate the cross-talk between metabolism and pathogenesis of Salmonella Typhimurium Salmonella enterica serovar Typhimurium (S. Typhimurium) can infect a wide range of host animals to cause diseases ... -
Cell Survival Strategies : Role Of Gyrase Modulatory Proteins
(2010-07-21)A steady state level of negative supercoiling is essential for chromosome condensation, initiation of replication and subsequent elongation step. DNA gyrase, found in every eubacteria, serves the essential housekeeping ... -
Cellular and Molecular Features of the Response of Mycobacterium smegmatis to Rifampicin and Moxifloxacin Upon Prolonged Exposure
Bacterial persisters are a subpopulation of bacteria that can tolerate lethal concentrations of antibiotics. These are phenotypic variants that can give rise to drug‐susceptible population upon withdrawal of the antibiotic. ... -
Characterisation of new restriction endonucleases and molecular interaction studies with Kpnl restriction-modification system
Characterization of New Restriction Endonucleases and Molecular Interaction Studies with the KpnI Restriction-Modification System Abstract and Synopsis Introduction Type II restriction-modification (R-M) systems are the ...