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Notch1-Induced Survival Signaling And Its Implications In Cancer Therapeutics
(2009-04-15)
Notch receptors and ligands are type I transmembrane proteins that regulate
development and differentiation during cell-cell contact. There are four Notch receptor
homologues and five notch ligands, identified in humans ...
Mechanistic And Functional Insights Into Mycobacterium Bovis BCG Induced Expression Of Cyclooxygenase-2 : Implications For Immune Evasion Strategies
(2014-09-25)
Mycobacteria are multifaceted pathogens capable of causing both acute disease as well as an asymptomatic latent infection. Protective immunity against pathogenic mycobacteria depends principally on cell-mediated immunity ...
Modulation Of Bacterial Pathogenesis By Curcumin
(2014-07-03)
Foodborne diseases are one among the diseases with high morbidity and mortality rate. The concern is raised with the emergence of pathogenic strains that are resistant to the available set of antibiotics. Conventional ...
Insights Into The Contribution Of Hfq In Salmonella Pathogenesis : Possible Role In Immune Evasion And Vaccine Development
(2014-10-07)
Chapter I Introduction Salmonellae are facultative Gram-negative intracellular pathogens. Different serovars of it causes a variety of diseases in multiple hosts with different disease outcomes. Salmonella enterica serovar ...
Delineation Of Signaling Events Regulating Mycobacterium Bovis BCG Induced Expression Of MMR-9 And SPI6 : Possible Implications For Immune Subversion Mechanisms
(2013-08-30)
One key to the pathogenic potential of the mycobacteria lies in their capacity to resist destruction by infected macrophages and dendritic cells. Robust host immune responses during mycobacterial infection often involve a ...
Identification Of GAL102 Encoded UDP-Glucose 4, 6 Dehydratase Activity, As A Novel Virulence Factor In Candida Albicans
(2014-08-11)
Among fungal pathogens responsible for opportunistic infections, species of the genus Candida have a major role (Mitchell, 1998). Various Candida species cause superficial infections which can be cured by the currently ...