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    Metabolic Regulation of Gametocytogenesis in Malaria 

    Beri, Divya
    Plasmodium sp. is an obligate intracellular protozoan parasite causing malaria and is responsible for more than 500,000 human deaths annually. P. falciparum and P. vivax are the two major species causing malaria in humans. ...
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    Systems biology approach to dissect Salmonella-host interactions 

    Banerjee, Pip
    Systems understanding of the biological data is required to capture the complex biochemical information when a pathogen interacts with its host. Such interactions are dynamic and complex, especially because various components ...
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    A systems-level exploration of host responses across the disease spectrum of Tuberculosis and COVID-19 

    Banerjee, Ushashi
    The host immune system orchestrates a defense mechanism against any invading pathogen with a combination of many mechanisms including antibody production, T-cell response, and memory response. The manner and extent of host ...
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    Understanding the role of mtHsp70 in regulating mitochondrial homeostasis: revealing its significance in Congenital Sideroblastic Anemia progression 

    Vishwanathan, Vinaya
    Mitochondria are ubiquitous organelles placed at the nexus of several metabolic and signaling pathways essential for cell survival. Therefore, maintaining a healthy and functional organelle becomes paramount for the cell. ...
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    Understanding the architecture of mitochondrial presequence translocase machinery and its implications in ALS progression 

    Waingankar, Tejashree Pradip
    The current thesis describes the structural organization of the presequence translocase machinery and its functional association with ALS pathogenesis. The TIM23 complex is essential for the mitochondrial biogenesis of ...
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    Substrate interrogation of the CRISPR-Cas12a endonuclease reveals an unexpected functional plasticity 

    Bhattacharya, Supreet
    Substrate interrogation of the CRISPR-Cas12a endonuclease reveals an unexpected functional plasticity Currently, Cas9 and Cas12a (also known as Cpf1) are the sole members of a large family of RNA-guided nucleases that ...
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    Exploring the role of low complexity protein sequence in regulating RNA granule dynamics and translation control 

    Roy, Raju
    RNA granules are conserved membraneless mRNP complexes that play an important role in determining mRNA fate by affecting translation repression and mRNA decay. Processing bodies (P-bodies) harbor enzymes responsible for ...
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    Flavivirus RNA replication: Probe development, structural dynamics, and role of zinc ions. 

    Srinivasa, Ramya
    Flaviviruses share a typical genome architecture where the highly conserved UTRs flank a central coding region. They also share a common genome replication strategy called genome cyclization where the UTRs interact to form ...
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    AuthorBakshi, Arindam (1)Balagopal, Deepa (1)Banerjee, Pip (1)Banerjee, Ushashi (1)Beri, Divya (1)Bhattacharya, Supreet (1)Bhatter, Nupur (1)Chakraborty, Subhashish (1)Dey, Trishna (1)Ganguli, Debayan (1)... View MoreSubjectNATURAL SCIENCES (38)Cancer (3)Mitochondria (3)DNA double-strand breaks (2)Helicobacter pylori (2)Pichia pastoris (2)SUMOylation (2)Taxol (2)Abrin (1)Acetylation (1)... View MoreHas File(s)Yes (38)

    etd@IISc is a joint service of SERC & J R D Tata Memorial (JRDTML) Library || Powered by DSpace software || DuraSpace
    Contact Us | Send Feedback | Thesis Templates
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