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    • Browsing Biochemistry (BC) by Title
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    Browsing Biochemistry (BC) by Title

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      • Role of Mycobacterium Tuberculosis RecG Helicase in DNA Repair, Recombination and in Remodelling of Stalled Replication Forks 

        Thakur, Roshan Singh (2018-05-14)
        Tuberculosis, caused by the infection with Mycobacterium tuberculosis remained as a major global health challenge with one third of world population being infected by this pathogen. M. tuberculosis can persist for decades ...
      • Role of Mycobacterium tuberculosis UvrD1 and UvrD2 helicases in resolving G-quadruplex DNA structures 

        Saha, Tias
        Unresolved G-quadruplex (G4) DNA secondary structures impede DNA replication and can lead to DNA breaks and to genome instability. Helicases are known to unwind G4 structures and thereby facilitate genome duplication. ...
      • Role of RTEL1 helicase in the regulation of homologous recombination during DNA replication 

        Dixit, Suruchi Dayanand
        Homologous recombination (HR) plays an essential role in the repair of DNA double-strand breaks (DSBs), replication stress responses, and genome maintenance. Although the mechanism of HR has been extensively studied in the ...
      • The Role of Saccharomyces Cerevisiae MRX Complex and Sae2 in Maintenance of Genome Stability 

        Ghodke, Indrajeet Laxman (2018-06-11)
        In eukaryotes, the repair of DSBs is accomplished through two broadly defined processes: Non-Homologous End Joining (NHEJ) and Homologous Recombination (HR). The central step of HR is pairing and exchange of strands between ...
      • Roles Of CTLA4(CD 152)-CD80/CD86 Costimulatory Interactions In Modulation Of Primary Mouse CD4' T Cell Cycle Progression And Survival 

        Mukherjee, Sambuddho (2011-05-04)
      • Roles Of Interferon-Modulated Genes In Cell Surface Expression Of Major Histocompatibility Complex Encoded Class I Molecules And Cell Survival In The Hepatoma Cell Line, H6 

        Prasanna, S Jyothi (2011-08-19)
      • Roles of Protein Acetylation in the Human Pathogen Helicobacter pylori 

        Kumar, Amrendra
        Helicobacter pylori is a gram-negative epsilon proteobacterium infecting half of the world population. H. pylori is a naturally competent bacterium with a huge repertoire of Restriction-Modification (RM) systems. The ...
      • Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution 

        Tripathi, Pankaj (2010-09-30)
        Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ...
      • Stop codon readthrough in MTCH2 mRNA and its role in mitochondrial physiology 

        Lekha, E M
        Stop codon readthrough is the process in which translation continues beyond a stop codon till a downstream, in-frame stop codon generating a polypeptide with a C-terminal extension. MTCH2 was selected as a potential ...
      • Stop codon readthrough of NNAT mRNA and its role in neuronal differentiation 

        Pandit, Madhuparna
        Protein synthesis terminates at the first stop codon encountered by the ribosome. In stop codon readthrough, translation termination is suppressed, enabling the ribosomes to continue translation beyond the canonical stop ...
      • Structural and Biochemical Analysis of DNA Processing Protein A (DprA) from Helicobacter Pylori 

        Dwivedi, Gajendradhar R (2018-05-09)
        H. pylori has a panmictic population structure due to high genetic diversity. The homoplasy index for H. pylori is 0.85 (where 0 represents a completely clonal organism and 1.0 indicates a freely recombining organism) which ...
      • Structural And Functional Characterization Of Calcium-Dependent Protein Kinase (CaCDPK1) From Cicer Arietinum : Effects Of Autophosphorylation And Membrane Phospholipids 

        Dixit, Ajay Kumar (2016-07-11)
        In plants, calcium is a ubiquitous signaling molecule and changes in cytosolic calcium levels reported in response to various abiotic and biotic stresses like salt stress, drought, pathogen attack and phytohormone signaling. ...
      • Structural and Functional Characterization of Quadruplex DNA Structures in Human Acetyl-CoA Carboxylase 1 Gene Promoters and Stabilization of G-quadruplex DNA by Carbazole-benzimidazole Conjugates 

        Kaulage, Mangesh Hanumant
        A number of studies have established that DNA targeting is a successful strategy in anticancer therapy. In recent years, however, the focus has shifted from double-stranded DNA to alternative DNA motifs such as G-quadruplex ...
      • Structure Elucidation and Biological Evaluation of a Novel Steroidal Saponin, Cholestanol Glucoside Isolated from Saraca Asoca Enodophytic Fuungus, Lasiodiplodia Theobromae 

        Valayil, Jinu Mathew (2018-05-16)
        Although the molecular mechanisms underlying the onset and progression of cancer has been unraveled to a great extend, cancer continues to remain a leading cause of death around the world. Clinical efficacy of the existing ...
      • Structure-Function Analysis Of Zinc Finger Domains Of Spermatidal Protein TP2 

        Meetei, Amom Ruhikanta (2012-02-24)
      • Structure-Function And Mechanistic Studies On KpnI DNA Methyltransferase 

        Shivakumara, B (2011-08-22)
      • Structure-Function Relationships of Saccharomyces Cerevisiae Meiosis Specific Hop 1 Protein : Implications for Chromosome Condensation, Pairing and Spore Formation 

        Khan, Krishnendu (2018-03-07)
        Meiosis is a specialized type of cell division essential for the production of four normal haploid gametes. In early prophase I of meiosis, the intimate synapsis between homologous chromosomes, and the formation of chiasmata, ...
      • Studies On Cloning And Characterization Of GnRH Receptor From The Pituitary Of Bonnet Monkey (Macaca Radiata) And Functional Studies With The Antiserum To GnRH Receptor 

        Santra, Sumana (Indian Institute of Science, 2005-11-23)
        GnRH is a decapeptide hormone, which plays a major role in the process of mammalian reproduction. It is synthesized by the hypothalamus and binds to its cognate receptor on the pituitary, to bring about the release of ...
      • Studies On DNA Mismatch Repair Nicking Endonucleases Of Haemophilus Influenzae And Neisseria Gonorrhoeae 

        Duppatla, Viswanadham (2010-01-01)
        DNA mismatch repair ensures faithful transmission of genetic material from parents to progeny, which is required for the survival of the organism. The studies on E. coli MMR proteins have formed the basis for the study ...
      • Studies On Heat Shock Protein 60 From Plasmodium Falciparum 

        Padma Priya, P (2010-09-14)
        Malaria is caused by a protozoan parasite belonging to the genus Plasmodia. Plasmodium falciparum is responsible for the fatal form of human malaria. Spread of drug resistant parasites warrants for sound biological ...

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