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    • Browsing Biochemistry (BC) by Title
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    Browsing Biochemistry (BC) by Title

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      • Selective Binding Of Meiosis-Specific Yeast Hop1 Protein, or Its ZnF Motif, To The Holliday Junction Distorts The DNA Structure : Implications For Junction Migration And Resolution 

        Tripathi, Pankaj (2010-09-30)
        Saccharomyces cerevisiae HOP1, which encodes a component of the synaptonemal complex, plays an important role in both gene conversion and crossing over between homologs, as well as enforces the meiotic recombination ...
      • Stop codon readthrough in MTCH2 mRNA and its role in mitochondrial physiology 

        Lekha, E M
        Stop codon readthrough is the process in which translation continues beyond a stop codon till a downstream, in-frame stop codon generating a polypeptide with a C-terminal extension. MTCH2 was selected as a potential ...
      • Stop codon readthrough of NNAT mRNA and its role in neuronal differentiation 

        Pandit, Madhuparna
        Protein synthesis terminates at the first stop codon encountered by the ribosome. In stop codon readthrough, translation termination is suppressed, enabling the ribosomes to continue translation beyond the canonical stop ...
      • Structural and Biochemical Analysis of DNA Processing Protein A (DprA) from Helicobacter Pylori 

        Dwivedi, Gajendradhar R (2018-05-09)
        H. pylori has a panmictic population structure due to high genetic diversity. The homoplasy index for H. pylori is 0.85 (where 0 represents a completely clonal organism and 1.0 indicates a freely recombining organism) which ...
      • Structural And Functional Characterization Of Calcium-Dependent Protein Kinase (CaCDPK1) From Cicer Arietinum : Effects Of Autophosphorylation And Membrane Phospholipids 

        Dixit, Ajay Kumar (2016-07-11)
        In plants, calcium is a ubiquitous signaling molecule and changes in cytosolic calcium levels reported in response to various abiotic and biotic stresses like salt stress, drought, pathogen attack and phytohormone signaling. ...
      • Structural and Functional Characterization of Quadruplex DNA Structures in Human Acetyl-CoA Carboxylase 1 Gene Promoters and Stabilization of G-quadruplex DNA by Carbazole-benzimidazole Conjugates 

        Kaulage, Mangesh Hanumant
        A number of studies have established that DNA targeting is a successful strategy in anticancer therapy. In recent years, however, the focus has shifted from double-stranded DNA to alternative DNA motifs such as G-quadruplex ...
      • Structure Elucidation and Biological Evaluation of a Novel Steroidal Saponin, Cholestanol Glucoside Isolated from Saraca Asoca Enodophytic Fuungus, Lasiodiplodia Theobromae 

        Valayil, Jinu Mathew (2018-05-16)
        Although the molecular mechanisms underlying the onset and progression of cancer has been unraveled to a great extend, cancer continues to remain a leading cause of death around the world. Clinical efficacy of the existing ...
      • Structure-Function Analysis Of Zinc Finger Domains Of Spermatidal Protein TP2 

        Meetei, Amom Ruhikanta (2012-02-24)
      • Structure-Function And Mechanistic Studies On KpnI DNA Methyltransferase 

        Shivakumara, B (2011-08-22)
      • Structure-Function Relationships of Saccharomyces Cerevisiae Meiosis Specific Hop 1 Protein : Implications for Chromosome Condensation, Pairing and Spore Formation 

        Khan, Krishnendu (2018-03-07)
        Meiosis is a specialized type of cell division essential for the production of four normal haploid gametes. In early prophase I of meiosis, the intimate synapsis between homologous chromosomes, and the formation of chiasmata, ...
      • Studies On Cloning And Characterization Of GnRH Receptor From The Pituitary Of Bonnet Monkey (Macaca Radiata) And Functional Studies With The Antiserum To GnRH Receptor 

        Santra, Sumana (Indian Institute of Science, 2005-11-23)
        GnRH is a decapeptide hormone, which plays a major role in the process of mammalian reproduction. It is synthesized by the hypothalamus and binds to its cognate receptor on the pituitary, to bring about the release of ...
      • Studies On DNA Mismatch Repair Nicking Endonucleases Of Haemophilus Influenzae And Neisseria Gonorrhoeae 

        Duppatla, Viswanadham (2010-01-01)
        DNA mismatch repair ensures faithful transmission of genetic material from parents to progeny, which is required for the survival of the organism. The studies on E. coli MMR proteins have formed the basis for the study ...
      • Studies On Heat Shock Protein 60 From Plasmodium Falciparum 

        Padma Priya, P (2010-09-14)
        Malaria is caused by a protozoan parasite belonging to the genus Plasmodia. Plasmodium falciparum is responsible for the fatal form of human malaria. Spread of drug resistant parasites warrants for sound biological ...
      • Studies on inflammatory responses: Roles of Interferon-gamma in macrophage activation and Nitric oxide synthase 2 during Salmonella Typhimurium infection-induced sepsis 

        Yadav, Shikha
        Inflammation is a complex set of immune responses that is critical for survival during injury or infection. It is also crucial for maintenance of tissue homeostasis under myriad conditions caused by cellular stress and ...
      • Studies on Novel Functional Responses of Mouse Peritoneal Macrophages to Interferon-gamma : Roles of Nitric Oxide Synthase 2 

        Chandrasekar, Bhagawat S (2018-04-18)
        Interferons are known cytokines that display antiviral, anti-proliferative and immuno-modulatory functions in the host. Interferon-gamma (Ifnγ) is the only type II family interferon that binds to the heterodimeric receptor ...
      • Studies On Polypyrimidine Tract Binding Protein : Identification Of Interacting Partners 

        Ramesh, V (2010-03-26)
        PTB (HnRNP I) is a multifunctional RNA binding protein which participates in a variety of RNA metabolic processes put together called as post transcriptional gene regulation. It interacts with shuttling hnRNPs L, K and E2 ...
      • Studies On The Functional Roles Of Peptidase N, A M1 Family Member, During Stress And Infection 

        Bhosale, Manoj (2014-08-11)
        The cytosolic protein degradation pathway, performed by ATP-dependent proteases and ATP-independent peptidases, plays important roles in several cellular activities, e.g. cell division, cell cycle progression, intracellular ...
      • Studies On The Mechanisms Involved In Thymic Atrophy During Salmonella Enterica Serovar Typhimurium Infection 

        Deobagkar-Lele, Mukta (2015-09-04)
        T lymphocytes are an essential component of the adaptive immune response and are highly versatile in function. Each T cell has a unique T cell receptor that can recognize an antigenic peptide in the context of the major ...
      • Studies On The Molecular Mechanism Of Cytokinin Action: Involvement Of Ca2+, Protein Kinase And Concurrent Protein Synthesis In Signaling Of Cytokinin-Induced Expression Of Pathogenesis-Related Enzymes In Cucumber 

        Barwe, Sonali P (Indian Institute of Science, 2005-12-08)
        Phytohormones act as signals to regulate plant growth and development by modulation of gene expression in response to internal developmental cues or external environmental stimuli, such as light and pathogen infection. ...
      • Studies on the post-transcriptional regulation of genes of glutamate utilization pathway in Pichia pastoris and a role for Retrograde regulation protein 1 

        Dey, Trishna
        The methylotrophic yeast, Pichia pastoris can utilize compounds such as glucose, glycerol, methanol, acetate, amino acids, or oleic acid as the sole source of carbon. However, the regulation of synthesis of key enzymes of ...

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