Organic Chemistry (OC): Recent submissions
Now showing items 61-80 of 212
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Design and Synthesis of Peptidomimics Constrained in Helical and Sheet Conformations using a Novel Covalent Surrogate for the Peptide Main Chain Hydrogen Bond
(2018-07-20)This thesis entitled “Design and Synthesis of Peptidomimics Constrained in Helical and Sheet Conformations Using a Novel Covalent Surrogate for the Peptide Main Chain Hydrogen Bond” is divided into six chapters. Chapter ... -
Total Synthesis of Bio-Active Macrolide Natural Products and Sulfinamide Based Ligands in Asymmetric Catalysis
(2018-07-18)The thesis entitled “Total synthesis of bio-active macrolide natural products and sulphonamide based ligands in asymmetric catalysis” is divided into two chapters. First chapter of the thesis describes the total synthesis ... -
Palladium Catalyzed Refunctionalizations of Olefins : Novel Strategies for Construction of C-C, C-Hetero Bonds and Homogeneous Hydrogenation
(2018-07-18)Chapter 1: Metal carbenoids in organic synthesis The chapter describes the phenomena of metal carbenoid insertion reactions in two parts: Part A, and Part B. The study of N-tosylhydrazones as diazo precursor was commenced ... -
Construction of Complex Polycyclic Systems using Gold Catalyzed Intramolecular Diyne/Enyne/ Hydroalkoxylation Reactions
(2018-07-18)First section of chapter 1 deals with gold catalyzed synthesis of ring fused furo[3,2,b]pyrans and furo[3,2,b]furans. Furo[3,2,b]pyrans and furo[3,2,b]furans are ubiquitous structural segments found in a number of natural ... -
Alkynones Derived from Tartaric Acid : Efficient Building Blocks for the Synthesis of Macrolactone Natural Products
(2018-07-05)The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb amide of tartaric acid in the total synthesis of macrolactone natural products. The thesis is divided into three sections. ... -
Organocatalytic Cascade Cyclizations for the Enantioselective Synthesis of Spirooxindoles
(2018-06-18)The thesis entitled “Organocatalytic Cascade Cyclizations for the Enantioselective Synthesis of Spirooxindoles” is divided into three chapters. Chapter 1: Catalytic Enantioselective Michael Addition/Cyclization Cascade ... -
Hybrid Nanostructured Materials from Bile Acid Derived Supramolecular Gels
(2018-06-13)Research activities towards the self-assembly of small organic molecules building blocks which lead to form supramolecular gel has increased extensively during the past two decades. The fundamental investigations of the ... -
Design and Development of Metal-free Cross Dehydrogenative Coupling Reactions for the Construction of C-S, C-O and C-C bonds
(2018-06-13)The thesis entitled “Design and Development of Metal-Free Cross Dehydrogenative Coupling Reactions for the construction of C-S, C-O and C-C bonds” is divided into three Chapters. Chapter 1 is presented in five parts, which ... -
Controlling Stereochemistry at the Quaternary Center using Bifunctional (THIO)Urea Catalysis
(2018-06-05)The thesis entitled “Controlling Stereochemistry at the Quaternary Center Using Bifunctional (Thio)urea Catalysis” is divided into five chapters. Chapter 1: Catalytic Enantioselective Construction of Quaternary Stereocenters ... -
Studies of Poly(Propyl Ether Imine) Dendrimers as Synthetic SiRNA Delivery Vectors with Relevance to Hepatitis C Virus Inhibition
(2018-06-05)Dendrimers are synthetic macromolecules with branches-upon-branches structures, nanoscale dimensions and a high density of surface groups. Presence of multiple cationic sites in dendrimers permits their efficient nucleic ... -
Evolution of New Lipids and Molecular Gelators : Syntheses, Aggregation Properties and Applications
(2018-05-14)The thesis entitled “Evolution of New Lipids and Molecular Gelators: Syntheses, Aggregation Properties and Applications” elucidates the design, synthesis, aggregation properties and application of new lipids based on ... -
New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production
(2018-05-10)The thesis entitled “New DNA-Targeting Small Molecules as Potential Anticancer Agents and for in vivo Specificity toward Enhanced Silk Production” encompasses design, computational calculations, and syntheses of diverse ... -
Copper-Catalyzed Novel Oxidative Transformations : Construction of Carbon-Hetero Bonds
(2018-05-08)The thesis entitled “Copper-Catalyzed Novel Oxidative Transformations: Construction of Carbon-Hetero Bonds” is divided into two main sections. Section A deals with the utility of azide as a nitrogen source for C-N bond ... -
Novel Synthetic Strategies towards Acetylenic Biscarbamates/Biscarbonates and Organochalcogen Derivatives
(2018-05-01)Bisacetylenic cabamates/carbonates are most useful compounds in finger mark development, for the synthesis of polymeric gels and other material applications. Organochalogen derivatives are the organic compounds containing ... -
Organic Transformations in Water : Synthetic and Mechanistic Studies towards Green Methodologies
(2018-04-12)This thesis entitled “Organic Transformations in Water: Synthetic and Mechanistic Studies towards Green Methodologies” is in two parts. Part-I describes various synthetic studies aimed at developing improved methodologies; ... -
A Study of Supramolecular Gels and Self Assembly of Novel Bile Acid Conjugates
(2018-04-02)Chapter 1: Functional and Responsive Supramolecular Gels In this chapter ‘supramolecular gels’ derived from small organic molecules with molecular mass of typically less than 2000 daltons are discussed. Representative ... -
Enantiospecific Total Synthesis of Phomopsolide B, Macrosphelides A & E and Total Synthesis & Determination of Absolute Configuration of Synargentolide B
(2018-03-24)Section I of the thesis deals with the enantiospecific total synthesis of phomopsolide B. Phomopsolide B was isolated from a strain of Phomopsis Oblonga. Enantiospecific total synthesis of phomopsolide B was accomplished ... -
Design and Application of Bile-Salt/Lanthanide Based Hydrogels
(2018-03-24)Chapter 1: Introduction to the luminescent properties of lanthanides Luminescence properties of trivalent lanthanides have been explored extensively over the past few decades owing to their unique properties. Lanthanides ... -
Studies On the Ring-Opening Reaftions Of Vinylcyclopropanes, Vinylcyclobutanes And Other Snmall-Ring Systems
(2018-03-06)The thesis entitled “Studies on the Ring-opening Reactions of Vinylcyclopropanes, Vinylcyclobutanes, and other Small-ring Systems” is divided into four chapters. Chapter 1: Part A: Bromenium Catalyzed Tandem Ring-openin ... -
Design, Synthesis and Applications of Novel Thiosugars & Amino Acid Derivatives
(2018-03-03)Glycosidases are carbohydrate processing essential enzymes necessary for the growth and development of all organisms such as intestinal digestion, post-translational processing of glycoproteins and the lysosomal catabolism ...