Organic Chemistry (OC): Recent submissions
Now showing items 81-100 of 214
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Studies On the Ring-Opening Reaftions Of Vinylcyclopropanes, Vinylcyclobutanes And Other Snmall-Ring Systems
(2018-03-06)The thesis entitled “Studies on the Ring-opening Reactions of Vinylcyclopropanes, Vinylcyclobutanes, and other Small-ring Systems” is divided into four chapters. Chapter 1: Part A: Bromenium Catalyzed Tandem Ring-openin ... -
Design, Synthesis and Applications of Novel Thiosugars & Amino Acid Derivatives
(2018-03-03)Glycosidases are carbohydrate processing essential enzymes necessary for the growth and development of all organisms such as intestinal digestion, post-translational processing of glycoproteins and the lysosomal catabolism ... -
Enantiospecific Synthesis Of DI- and Linear Triquinanes
(2018-02-22)Employing a chiral pool strategy, enantiospecific syntheses of di- and triquinanes have been accomplished. α-Campholenaldehyde 95, readily available from the abundantly available monoterpene α-pinene 94, has been utilised ... -
Synthesis, Structural and Biophysical Studies of Oligosaccharide Glycolipids and Glycosidic Bond Expanded Cyclic Oligosaccharides
(2018-02-15)Pathogenesis originating from mycobacterial invasion on host cells is prevalent and is a major challenge in efforts towards overcoming the burden of mycobacterial diseases. Complex architecture of mycobacterium cell wall ... -
Studies on the Stereoselective Geminal and Vicinal Heterodifunctionalization of Alkenes
(2018-02-14)The thesis entitled “Studies on the Stereoselective Geminal and Vicinal Heterodifunctionalization of Alkenes” consists of three chapters. Chapter 1: Part A: Bromonium Ion Mediated Stereoselective Geminal Aminooxygenation ... -
Synthesis of Bivalent and Monovalent Sugar Ligands, their Interfacial and Solution Phase Lectin Bindng Studies
(2018-02-11)Carbohydrate-protein interactions are responsible for several biological functions. While these interactions maintain high levels of specificities, the binding strength of individual carbohydrate-protein recognitions are ... -
Regioselective Functionalization of Indoles using Directing Group Strategy : An Efficient Transition Metal Catalysis
(2018-02-07)The thesis entitled “Regioselective Functionalization of Indoles using Directing Group Strategy: An Efficient Transition Metal Catalysis” is divided into two sections. Section A, which is presented in three chapters, ... -
Investigating the Intercarbonyl X...C' (X=O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of charge->II* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics
(2018-02-06)This thesis entitled “Investigating the Intercarbonyl X···C′ (X = O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of Charge→π* Interactions. Synthesis and Characterization of Thioimidate Isostere ... -
Iodine and Copper Catalyzed Oxidative Cross Coupling Reactions : Design and Development of Carbon-Carbon and Carbon-Heteroatom Bond Forming Reactions
(2018-01-17)Design and Development of Carbon-Carbon and Carbon-Heteroatom Bond Forming Reactions” is divided into two sections. Section-A, contains two chapters, describes the catalytic ability of iodine for cross coupling reactions. ... -
Enantiospecific Total Synthesis of Indole Alkaloids Eburnamonine, Aspidospermidine, Quebrachamine, Henrycinols A and B and Synthesis of Azepino [4,5 -b] Indolones
(2018-01-07)The thesis entitled “Enantiospecific total synthesis of indole alkaloids eburnamonine, aspidospermidine, quebrachamine, henrycinols A and B and synthesis of azepino[4,5-b]indolones” is divided into three chapters. ... -
Novel Redox Responsive Cationic Lipids, Lipopolymers, Glycolipids And Phospholipid-Cationic Lipid Mixtures : Syntheses, Aggregation And Gene Transfection Properties
(2018-01-07)The thesis entitled “Novel Redox Responsive Cationic Lipids, Lipopolymers, Glycolipids and Phospholipid-Cationic Lipid Mixtures: Syntheses, Aggregation and Gene Transfection Properties” elucidates the design, ... -
Lanthanide Based Hydrogels in Sensing, Energy Transfer and Nanoparticle Synthesis
(2018-01-04)Chapter 1: Luminescence property of lanthanide and its applications Lanthanides are well-known for their unique luminescence property and have found widespread applications in sensing, bioimaging, lasers, optoelectronic ... -
Total Synthesis of Bio-active Natural Products Gabosines, Crassalactone C, Anamarine and Iriomoteolide 3a
(2018-01-03)First chapter of the thesis describes the desymmetrization of the bis-dimethyl amide 1 derived from tartaric acid with vinyl Grignard reagents and subsequent reduction of the resultant -keto amides 2a-c to the -hydroxy ... -
Bile Acid based Supramolecular Gels, Soft Hybrid Materials and their Applications
(2017-12-16)Chapter 1. Supramolecular Gels and their Applications Supramolecular gels are viscoelastic materials composed of a solid like three dimensional fibrillary network that is embedded in a liquid. Supramolecular gels are derived ... -
Synthesis, Conformation and Glycosidic Bond Stabilities of Septanoside Sugars
(2017-12-12)Seven-membered cyclic sugars, namely, septanoses and septanosides, are less commonly known sugar homologues. Synthesis of septanoses arise an interest due to their configurational and conformational features and the ... -
Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins : Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond
(2017-12-03)This thesis titled, “Nature of Local Interactions at cisPro-Aro Peptide Sequences in Proteins: Evidences for van der Waals type Interactions. Design and Synthesis of Novel Covalent Surrogates for the Peptide Hydrogen Bond”, ... -
Synthesis And Characterization of Cationic Lipids And Carbon Nanomaterials Based Composites for the Delivery Of Bioactive Oligo/Polynucleotides and Drugs In Vitro and In Vivo
(2017-11-27)The biggest hurdle in success of gene and drug therapy is designing and preparation of suitable bio-nanomaterials to carry the desired nucleic acid and drug to the targeted site. The work described in the present thesis ...