Browsing Organic Chemistry (OC) by Title
Now showing items 1-20 of 223
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2,3-Dideoxy Sugars in Glycoconjugations and Cyclic Oligosaccharide Synthesis
2,3- Dideoxy sugars are versatile synthons for organic synthesis. The applications are diverse in biological systems and organic synthesis. In the first part of the thesis, 2,3-unsaturated sugars are used for the ... -
Achieving Efficiency and Specificity in Multifarious Systems for Anti-cancer Gene Therapeutics
The research work described in this thesis encompasses the syntheses, characterization and bioactivity determination of various novel systems crafted for achieving high efficacy and targeted gene therapeutic effect in ... -
Alkynones Derived from Tartaric Acid : Efficient Building Blocks for the Synthesis of Macrolactone Natural Products
(2018-07-05)The thesis describes the synthesis and application of various alkynones derived from the bis-Weinreb amide of tartaric acid in the total synthesis of macrolactone natural products. The thesis is divided into three sections. ... -
Allylic Halogenation Route to Latent-Active Trans-Glycosylation of Allyl Glycoside Donors
Allylic halogenation of allyl glycosides as a new route to allyl glycoside donors in glycosylations is investigated in this thesis. Allyl functionality is one of the commonly adopted protecting groups to hydroxyl groups ... -
Analytical Applications of Bile Acid-derived Soft Materials
Supramolecular gels are soft materials with solid-like properties such as supporting weight and retaining shape; and some liquid-like features which make them injectable, printable, etc. On the other hand, lanthanide-based ... -
Asymmetric Synthesis of Amino Acid Derivatives and Total Synthesis of Biologically Active Natural Products
The thesis describes the development of synthetic method for the synthesis of -amino acid esters, amides, thioesters using Ellman sulfinimines. The procedure developed was further utilized in the synthesis of di and tri ... -
Asymmetric Synthesis Of Troger's Base Analogues And Studies In Molecular Recognition
(Indian Institute of Science, 2005-04-25)Troger's base was the first amine to be resolved where the chirality was due to solely very high inversion barrier around nitrogen atom. Though the molecule was known for over a century, work done during the past decade ... -
Benzimidazole Based Novel Ligands For Specific Recognition Of Duplex And G-Quadruplex DNA
(2013-07-17)The thesis entitled “Benzimidazole based Novel Ligands for Specific Recognition of Duplex and G-Quadruplex DNA” deals with the design, synthesis and modeling of several benzimidazole based molecules and their interaction ... -
Bile Acid Based Molecular Tweezers And Crown Ethers
(Indian Institute of Science, 2005-05-02)Chapter 1. Introduction to Molecular Tweezers Whitlock and Zimmerman developed a class of molecular hosts, popularly known as molecular tweezers, which sandwich aromatic guests by ii=ii interaction. Chapter 1 summarizes ... -
Bile Acid Based Supramolecular Gels, Semiconductor Nanocrystals And Soft Hybrid Materials
(2016-04-12)Chapter 1. General Introduction This chapter gives an introduction to supramolecular organo/hydrogels and the related bile acid chemistry touching upon the gelation properties of the bile acid derivatives. Diverse ... -
Bile Acid based Supramolecular Gels, Soft Hybrid Materials and their Applications
(2017-12-16)Chapter 1. Supramolecular Gels and their Applications Supramolecular gels are viscoelastic materials composed of a solid like three dimensional fibrillary network that is embedded in a liquid. Supramolecular gels are derived ... -
Bile Acid Derived Adaptive Dendrons And Anion Receptors
(2011-02-15)Chapter 1. Bile acid derived adaptive dendrons Bile acids are naturally occurring rigid, chiral molecules with unique facial amphiphilicity making it an attractive build block for designing supramolecular systems. ... -
Bile Acid-Based Chiral Auxiliaries In Asymmetric Synthesis
(2012-12-10) -
Bile Salts in Supramolecular Chemistry: Synthesis of Fluorescent Nanoclusters, Oxide Nanoflowers, and Anion Effect on Metallogels
In summary, we have explored an interesting pH-dependent sensitization of Tb(III) using methyl salicylate (MS) as a sensitizer in aqueous media. Methyl salicylate was found to be a specific sensitizer for Tb(III) but not ... -
Breaking Symmetry – Organocatalytic Enantioselective Synthesis of Natural and Unnatural Ladderanes
Architecturally unique compounds produced by nature have remained a source of inspiration for organic chemists. Ladderane phospholipids (such as [5][3]PC and [3][3]PC), isolated in the year 2002 from anaerobic ammonium oxidizing ... -
C-H Bond Functionalization and Tandem Cyclization with Alkynoates and Maleimides Using Directing Group Strategy
The thesis presents manganese‒ and rhodium‒catalyzed C‒H bond activation and tandem cyclization reactions. These reactions lead to the construction of carbon‒carbon bonds using directing group strategy. The thesis is divided ... -
Carbon-Carbon and Carbon Heteroatom Bond Forming Reactions: From Organocatalysts to Quantum Dots
Butenolides containing stereogenic centers on the ring, are commonly encountered structural motifs, found in many natural products. Consequently, there has been considerable interest in efficient and stereoselective ... -
Catalytic Asymmetric Direct and Vinylogous Aldol, Michael and Alkylation Reactions
Pyrazoles and pyrazolones are a highly explored and privileged class of aza-heterocycles with a wide range of applications, thereby rendering a recurring interest in their synthesis and functionalization. Majority of the ...