Organic Chemistry (OC): Recent submissions
Now showing items 41-60 of 214
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Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding
Thesis titled, “Design, Synthesis and Conformational Analysis of Hydrogen Bond Surrogate (HBS) Stabilized Helices in Natural Sequences. Helically Constrained Peptides for Potential DNA-Binding”, describes the development ... -
Synthetic Applications of C-2 Substituted Glucal
This report concerns the development of a synthetic approach towards synthesis of seven-membered septanosides, such as, substituted oxepanes from protected 2-hydroxyglycals. Important precursors to the synthesis of the ... -
Stereocontrol through Catalytic Enantioselective C(sp2)−H and C(sp3)−H Alkylation: From Bifunctional Organocatalysis to Iridium-Catalysis
This thesis, entitled “Stereocontrol through Catalytic Enantioselective C(sp2)−H and C(sp3)−H Alkylation: From Bifunctional Organocatalysis to Iridium-Catalysis” primarily deals with the development of various catalytic ... -
Achieving Efficiency and Specificity in Multifarious Systems for Anti-cancer Gene Therapeutics
The research work described in this thesis encompasses the syntheses, characterization and bioactivity determination of various novel systems crafted for achieving high efficacy and targeted gene therapeutic effect in ... -
Nucleophilic Addition reactions of 2-Aza-allyl anion: Application to the Total Synthesis of Natural Products
The thesis entitled “Nucleophilic Addition reactions of 2-Aza-allyl anion: Application to the Total Synthesis of Natural Products’’ is divided into two sections with an appendix. First section of the thesis details the ... -
Development of Stimuli-Responsive Self-Assembled Materials for Biomolecular Applications
The thesis entitled ‘‘Development of Stimuli-Responsive Self-Assembled Materials for Biomolecular Applications’’ deals with the design, synthesis, and characterisation of low molecular weight hydrogel systems as well as ... -
Design and Synthesis of Stimuli-responsive Gelators and Novel Gemini Surfactants and Characterization of their Properties upon Self-assembly
Chapter 1. A Brief Overview of Gemini Surfactants and Low Molecular-Weight Gelators (LMWGs) The first part of this chapter gives a brief account of the research done in the area of aqueous 3D-(ca. micelles and vesicles ... -
Bile Salts in Supramolecular Chemistry: Synthesis of Fluorescent Nanoclusters, Oxide Nanoflowers, and Anion Effect on Metallogels
In summary, we have explored an interesting pH-dependent sensitization of Tb(III) using methyl salicylate (MS) as a sensitizer in aqueous media. Methyl salicylate was found to be a specific sensitizer for Tb(III) but not ... -
Regioselective C-H Amidation Reactions using Directing Group Strategy and its Application in Organic Synthesis
The thesis represents an approach for the C-H bond activation using directing group strategy. The C-H activation happens through five/six-membered metallacycle through concerted metallation deprotonation. Further ... -
Properties and Applications of Metal Cholate Hydrogels
This thesis presents a detailed study on the unusual properties of silver cholate, applications of lanthanide cholate gels, enhanced luminescence of lanthanides by water, and the mechanism of formation of these gels. ... -
A Mitsunobu-Michael Reaction Sequence to N-Heterocyclic Variants and Ti(III)-Mediated Synthesis of Terpenoids and N-Fused Indoles
The research work delineates a flexible and novel route for the diastereoselective construction of diversely substituted N-heterocyclic variants as valuable scaffolds for natural products and pharmaceuticals, starting from ... -
Total Synthesis of Natural Products Diospongin a, Cryptofolione, CryptopyranmoscatoneB2, SCH725674 and Towards the Total Synthesis of Palmerolide C
First chapter of the thesis describes the total synthesis of tetrahydropyran containing natural products, diospongin A, cryptopyranmoscatone B2, hydroxy δ-lactone containing natural product cryptofolione and macrolactone ... -
Site-selective C-H Functionalization using Directing Group Strategy via C-H Bond Activation
The thesis entitled “Site-selective C-H Functionalization using Directing Group Strategy via C-H Bond Activation” is divided into two sections. Section A, is presented in four chapters, comprising the work on the aromatic ... -
Design, Synthesis and Properties of Novel Oligo-Phenylenevinylene based Supramolecular Photochromic Gels and Soft Composites with Nanomaterials
The thesis entitled “Design, Synthesis and Properties of Novel Oligo-Phenylenevinylene based Supramolecular Photochromic Gels and Soft Composites with Nanomaterials” deals with soft materials derived from low molecular ... -
β-Keto Phoshonates from Tartaric Acid in the Total Synthesis of (+)-4-epi-gabosine A, (+)-dihydrokawain-5-ol, (-)-bengamide E and indetification of MPK-09 : A Small Molecule that Restores the Wild type Function of Mutant p53
The thesis entitled “-Keto phosphonates from tartaric acid in the total synthesis of ()-4-epi-gabosine A, ()-dihydrokawain-5-ol, ()-bengamide E and Identification of MPK-09: A small molecule that restores the wild type ... -
Enantioselective Carbon-Carbon and Carbon-Heteroatom Bond Formation : From Bifunctional to Anion-Binding Catalysis
The thesis entitled “Enantioselective Carbon-Carbon and Carbon-Heteroatom Bond Formation: from Bifunctional to Anion-Binding Catalysis” is divided into four chapters. Chapter 1: Organocatalytic Asymmetric Direct Vinylogous ... -
Novel Strategies for the Synthesis of Organo-Sulfur Compounds under Metal-Free Reaction Conditions
(2018-09-04)The thesis titled “Novel Strategies for the Synthesis of Organo-Sulfur Compounds Under Metal-free Reaction conditions” is presented into three main sections. Section A– deals with the synthesis of thiourea and thioamide. Section ... -
Syntheses and Characterization of Novel Materials for Efficacious Anticancer Drug Delivery and Selective Sensing of Bioanalytes
(2018-08-02)The thesis entitled “Syntheses and Characterization of Novel Materials for Efficacious Anticancer Drug Delivery and Selective Sensing of Bioanalytes” encompasses the syntheses and characterization of various novel materials ...