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Functionalized Nanomaterial and Metallocycle for Selective Antibacterial, Diagnosis, and Anti-cancer Activity
The evolution of drug resistant bacteria has become a severe threat to public health globally. The misuse of conventional antibiotics has led to the development of multi-drug resistant bacteria. Even though antibiotics ...
Lanthanide-derived Photoluminescent Hydrogels for Analytical Screening of Norfloxacin, Ofloxacin, α-Chymotrypsin, and Gossypol
Supramolecular gels are soft substances made of elastic cross-linked three-dimensional network connected by noncovalent interactions such as hydrogen bonds, hydrophobic interactions, donor-acceptor interactions, π- π ...
Functionalized Low-Dimensional Nanomaterials in Antibacterial Activity and Drug Delivery
The rise in multi-drug-resistant bacterial infections is a major health concern of the 21st-century. Overuse of traditional antibiotics in medical, agricultural, and veterinary practices has led to numerous drug-resistant ...
Unleashing the Potential of Nanomaterials in Organic Synthesis: QD-based Photocatalysis and AuNP-catalysed Cascade Rearrangement Reaction
The thesis titled Unleashing the Potential of Nanomaterials in Organic Synthesis: QD-based Photocatalysis and AuNP-catalysed Cascade Rearrangement Reaction explores innovative strategies for organic synthesis using ...
Studies of Pyridoneimine in Site-Selective Functionalization of Carbohydrates and in Multivalent Phenomenon
Carbohydrates are functionally rich biomolecules with multiple hydroxy functionalities. As a result, the most often practiced chemical route is to install protecting groups that permit selective functionalization at the ...
Cp2Ti(III)Cl-Mediated Endo- and Exo-Radical Cyclization: Synthesis of a Tri-nor-guaiane Sesquiterpene Isoclavukerin A, Terpenoid Bicyclic Lactones and Synthetic Studies Towards the Total Synthesis of Scabrolide A
Radical cyclization strategy always gives an expedient access to complex molecular scaffolds present in many bioactive natural products. In this research work, a systematic study is undertaken to investigate the less ...
2,3-Dideoxy Sugars in Glycoconjugations and Cyclic Oligosaccharide Synthesis
2,3- Dideoxy sugars are versatile synthons for organic synthesis. The
applications are diverse in biological systems and organic synthesis. In the first part of the
thesis, 2,3-unsaturated sugars are used for the ...
Engineering of Nanomaterials: Application in Antibacterial Activity, Bio-Analyte Detection and Environmental Remediation
Infectious diseases caused by pathogenic bacteria are creating a global health problem. In the recent report of World Health Organization (WHO), it has been mentioned that around 7 lacks people are dying each year worldwide ...
HBS Constrained Antiparallel β-Sheets and Flat Toroid Turns; Homoserine, Thioamide and 1,3-Thiazine Containing Peptidomimetics: Design, Synthesis, Conformational Analyses and applications
In chemical biology, short peptidomimetic biological active models have been widely used for anti-microbial activity, drug development, catalysis, and amyloidogenesis. In this thesis, I have synthesized several unnaturally ...
Studies of Carbohydrate-Conjugated Anthracenes in Self-Assembly, Bioimaging and Photosensitization
Conjugation of a carbohydrate moiety to an aromatic core leads to glycostructures that possess a high propensity for self-assembly in aq. solutions, driven primarily by π-stacking of the aromatic ring, as well as, the ...