Division of Biological Sciences
Recent Submissions
-
Production of aromatic alcohols and hydroxy acids by candida species and the mode of action of aromatic alcohols
The thesis entitled “Alcohols and Hydroxy Acids by Candida Species and Their Mode of Action”, submitted by Mr. T. K. Narayanan for the Ph.D. degree of the Indian Institute of Science, Bangalore–560012, India. Yeasts, in ... -
Cyclic peptide disulfides as conformational models; synthesis and spectroscopic studies
The study of small peptides has been motivated both by the high biological activity manifested by many peptides and their potential use as model systems for understanding polypeptide and protein structure. The development ... -
conformational studies on hydrogen bonded cyclic hexapeptides
In the first place, the uniqueness of any MEC within a certain region demonstrates the successful incorporation of the hydrogen?bond energy function in a minimization program. In particular, its interpolation with the ... -
X-ray crystallographic studies on the structure and interactions of L-ascorbic acids
It is well known that non?covalent interactions endow biological systems with extreme subtlety and complexity. In fact, the structure and assembly of proteins, and the dynamical processes involved in their action, are ... -
CONFORMATION OF POLYNUCLEOTIDES
The conformations of the five?membered rings and other relevant conformational features of deoxyribose, ribose, and arabinose have been analysed in this chapter and in the preceding two chapters. The analysis included ... -
Spectroscopic studies on two biological amphiphiles: melittin and Birlirubin.
This thesis describes spectroscopic studies on two interesting biological amphiphiles, melittin and bilirubin. The former is a 26?residue polypeptide which comprises ~50% of the dry venom of honeybees. Melittin is cytotoxic ... -
Compact alwin grammar and algorithms for computer coding of organic chemical structures
Abstract not available -
Distinct Drivers of Type 2 Diabetes: A Systems Modeling Approach to Molecular, Genetic, and Metagenomic Insights
Type 2 Diabetes (T2D) is a complex and heterogeneous disease characterized by hyperglycemia, insulin resistance, and impaired insulin secretion. While often interrelated, hyperglycemia and insulin resistance represent ... -
Studies on the irreversible thermal denaturation of Rnase A
“STUDIES ON THE IRREVERSIBLE THERMAL DENATURATION OF RIBONUCLEASE A” SUBMITTED BY GIRISH SAHNI FOR THE Ph.D. DEGREE OF THE INDIAN INSTITUTE OF SCIENCE, BANGALORE–560012, INDIA** Processes whereby proteins and enzymes are ... -
Matabolism of phenylacetic acid by aspergillus niger
The metabolism of phenylacetic acid by Aspergillus niger was studied. The culture filtrates of A. niger grown on phenylacetate for 40 hours exhibited the presence of 2? and 3?hydroxyphenylacetic acids, 3?hydroxybenzyl ... -
Some aspects of the metabolism of mandelic acid by pseudomonas convexa, Ph.D. Thesis
The metabolism of mandelic acid (phenylglycolic acid) has been studied in detail in several bacteria, and it has been shown that the side chain of mandelic acid is first degraded, resulting in the formation of benzoic acid, ... -
Structural features of the initial active intermediate formed during acid denaturation of bovine pancreatic ribonuclease-A, Ph.D. Thesis
The present thesis deals with structural investigations of the initial products formed during acid denaturation of ribonuclease A. We have divided our observations into two sections. Section I The nature of the deamidation ... -
Indoeacetaldoxime hydro-lyase of gibberella fujikoroi
In the following pages, the work described in the preceding chapters has been summarized. The conversion of IAOX to IAN was shown to be an enzymatic process. Culture conditions for the growth of Gibberella fujikuroi ... -
Influence of vitamin B12 on the nutritive value of vegetable proteins
The work reported in this thesis relates to two main aspects: (a) To confirm and extend the finding that vitamin B?? counteracts the adverse effects of the tryptic and growth inhibitors present in raw soyabean. (b) To ... -
Characterizing the viral factors and host determinants that control Dengue virus infection and pathogenesis
Background – Dengue virus is a mosquito-borne flavivirus that is the causative agent for dengue fever, which progresses to dengue shock syndrome in many patients. It is estimated that around 390 million dengue infections ... -
Unraveling the layers of DNA with the DNA-PAINT brush
DNA is both the repository of genetic information and a versatile nanoscale material whose stability and function are governed by base pairing and base-stacking interactions. Despite their fundamental role in DNA structure, ...

