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Pranlukast as an Allosteric Inhibitor of M.Tuberculosis Ornithine Acetyltransferase : Implication Towards Novel Combinatorial Therapy
Tuberculosis (TB) is a deadly disease responsible for the death of approximately 1.5 million people each year, with the highest being from developing nations. Tuberculosis affects mostly the lungs, and other parts of the ...
From Transformation to Therapeutics : Diverse Biological Applications of Shock Waves
(2018-02-26)
Chapter–I Introduction
Shock waves appear in nature whenever the different elements in a fluid approach one another with a velocity larger than the local speed of sound. Shock waves are essentially non-linear waves that ...
Design and Characterization of HIV-1 ENV Derived Immunogens
(2018-06-21)
The Human Immunodeficiency Virus (HIV) is a member of the retroviridae family from lentivirus genus which primarily infects CD4+ T cells and also to lesser degree monocytes, macrophages, and dendritic cells causing progressive ...
Genetics of Glioma : Transcriptome and MiRNome Based Approches
(2018-03-26)
Glioma, the tumor of glial cells, is one of the common types of primary central nervous system (CNS) neoplasms. Astrocytoma is the most common of all gliomas and originates from astrocytic glial cells. Astrocytoma tumors ...
Molecular Ecology of the Primitively Eusocial Wasp Ropalidia Marginata : Relatedness, Queen Succession and Population Genetics
(2018-06-08)
Altruism is defined as a trait in an individual that increases some other individual’s fitness at the expense of her own. Therefore, existence of such traits in a population is an evolutionary paradox, as natural selection ...
Understanding the Regulatory Steps that Govern the Activation of Mycobacterium Tuberculosis σK
(2018-07-28)
A distinctive feature of host-pathogen interactions in the case of Mycobacterium tuberculosis is the asymptomatic latent phase of infection. The ability of the bacillus to survive for extended periods of time in the host ...
Transcriptional and Posttranscriptional Regulation of the Tumor Suppressor CDC73 in Oral Squamous Cell Carcinoma : Implications for Cancer Therapeutics
(2018-04-16)
CDC73, also known as HRPT2, is a tumour suppressor gene whose expression is lost or downregulated in parathyroid, renal, breast, uterine and gastric cancers. However, the reports regarding the role of CDC73 in oral squamous ...
Investigating Pattern Recognition And Bi-coordinate Sound Localization in the Tree Cricket Species Oecanthus Henryi
(2017-09-20)
Acoustic communication, used by a wide variety of animals, consists of the signaler, the signal and the receiver. A change in the behaviour of the receiver after reception of the signal is a prerequisite for communication. ...
Secondary Structures in Proteins : Identification and Analyses
(2018-07-12)
Proteins are large biomolecules consisting of one or more long chains of amino acid residues. They perform a vast array of functions within living organisms. In this thesis, we present analyses of different secondary ...
The Role of Nursery Size and Plant Phenology on the Reproduction of and Relationships within a Fig-fig Wasp Nursery Pollination System
(2018-05-09)
Obligate nursery pollination mutualisms such as the fig–fig wasp system, with their central plant–pollinator mutualism associated with non-pollinating satellite wasp species, can function as closed system microcosms ...