Starting with the structure analysis of ConA in the 70s, the crystal structures of hundreds of different lectins and their carbohydrate complexes have been determined. Lectins, multivalent carbohydrate-binding proteins ...

Decades long studies on plant lectins carried out in this laboratory have contributed substantially to glycobiology and helped in the initiation and development of macromolecular crystallography in India. Subsequently the ...

Lectins are proteins of non-immunologic origin that bind to carbohydrates with high fidelity. They constitute a large class of multivalent recognition molecules that specifically interact with their cognate sugar moieties ...

This thesis is concerned with structural and related studies on two non-toxic homologues of type II RIPs. Type II RIPs, which are more toxic than type I, contain an additional lectin chain (B-chain) covalently linked to ...

Lectins are a diverse group of proteins which can recognize different types of carbohydrates specifically and reversibly. Though first characterized in plants, lectins have now been identified in all other forms of life. ...

Biomolecular recognition is a fundamental principle underlying all cellular processes, driven by specific and tightly regulated interactions. This thesis explores the structural basis of recognition mechanisms in two ...

Lectins are multivalent carbohydrate-binding proteins which exert their biological effects through their ability to specifically bind different sugars. They occur in plants, animals, bacteria, and viruses. They exhibit ...